Results 221 to 230 of about 1,868,780 (302)

Cross‐Organ Multi‐Omics Profiling of Systemic Alterations in 5xFAD Mice and Changes Associated with Huanglian Jiedu Decoction Treatment

open access: yesAdvanced Science, EarlyView.
Cross‐organ multi‐omics reveals coordinated inflammatory and metabolic disturbances in 5xFAD mice. Huanglian Jiedu Decoction improves cognition and alleviates brain and liver abnormalities. Complementary hepatocyte–microglia conditioned‐medium experiments suggest PPAR‐γ involvement in treatment‐associated changes in microglial inflammation, providing ...
Wenya Gao   +10 more
wiley   +1 more source

pH‐Responsive Nanoplatform‐Mediated Lipid Hijacking and Metabolic Collapse for Synergistic Starvation‐Immunotherapy

open access: yesAdvanced Science, EarlyView.
A pH‐responsive ZIF‐8/2‐DG@Cu‐TA nanoplatform orchestrates multifaceted metabolic disruption for synergistic starvation‐immunotherapy. Acid‐triggered 2‐DG release blocks glycolysis, while Zn2+ overload induces mitochondrial dysfunction. Concurrently, Cx43‐mediated gap junctions redirect lipid droplets from tumor cells to cancer‐associated fibroblasts ...
Xianlong Zong   +9 more
wiley   +1 more source

Molecular MRI Reveals Macrophage‐Enriched Peritumoral Immune Remodeling After Incomplete Ablation in Liver Cancer

open access: yesAdvanced Science, EarlyView.
Incomplete microwave ablation (iMWA) induced a spatially organized, macrophage‐rich immunosuppressive tumor microenvironment (TME) in orthotopic VX2 liver tumors. Molecular MRI enhanced with europium‐doped very small superparamagnetic iron oxide nanoparticles (Eu‐VSOP) noninvasively visualized this remodeling, showing preferential nanoparticle ...
Yubei He   +22 more
wiley   +1 more source

Interface‐Confined Cavitation at an MXene/TiO2 Schottky Heterointerface for Non‐Thermal Juice Preservation

open access: yesAdvanced Science, EarlyView.
This work establishes an MXene/TiO2 Schottky heterointerface for non‐thermal sonocatalysis. Interface‐confined cavitation and dynamic Ti3+/V₀ shuttles drive charge transport and reactive oxygen species (ROS) generation. The platform achieves 3‐log pathogen reduction while retaining heat‐labile nutrients in complex food matrices, redefining sonocatalyst
Xiaoge Wu   +5 more
wiley   +1 more source

Synthesis of Alumina Nanoparticles Using Plasma-Induced Microbubbles. [PDF]

open access: yesMicromachines (Basel)
Minami Y   +4 more
europepmc   +1 more source

EHD‐LIFT: Electrohydrodynamic Laser Induced Forward Transfer

open access: yesAdvanced Science, EarlyView.
Electrohydrodynamic laser‐induced forward transfer (EHD‐LIFT) introduces electric field‐assisted control to LIFT. Through laser‐patterning a conductive absorber layer, local curvatures are induced in the donor film, enabling flow‐focusing for transfer of smaller droplets at lower laser energies.
Ankit Das   +5 more
wiley   +1 more source

Acoustic Streaming-Based 3D Cell Focusing and Plasma Separation. [PDF]

open access: yesMicromachines (Basel)
Zheng J   +6 more
europepmc   +1 more source

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