Results 51 to 60 of about 2,405,181 (305)

Plasma cell leukaemia

Porto Biomedical Journal, 2016
Plasma cell leukaemia (PCL) is a rare and aggressive disease. Diagnosis is made when there are >2000/#mL circulating plasma cells in peripheral blood or plasmacytosis >20% of total leukocyte count. We report a case of a 51-year old man with generalized bone pain and constitutional symptoms.
Braga, Carlos Galvão, Rodrigues, Ana Raquel, Alves, Marina, Portela, Catarina, Pinto, Luísa, Marques, Herlander   +5 more
openaire   +2 more sources

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi, Daisuke Katagiri, Takeyuki Watadani, Shunichi Matsuda, Hiroshi Kaneko, Noritoshi Arai   +5 more
wiley   +1 more source

CD11c+ B Cells Are Mainly Memory Cells, Precursors of Antibody Secreting Cells in Healthy Donors

Frontiers in Immunology, 2020
CD11c+ B cells have been reported to be increased in autoimmune diseases, but they are detected in the blood of healthy individuals as well. We aimed to characterize CD11c+ B cells from healthy donors by flow cytometry, microarray analysis, and in vitro ...
Marie-Laure Golinski, Marie-Laure Golinski, Mélanie Demeules, Céline Derambure, Gaetan Riou, Maud Maho-Vaillant, Maud Maho-Vaillant, Olivier Boyer, Olivier Boyer, Pascal Joly, Pascal Joly, Sébastien Calbo   +11 more
doaj   +1 more source

Spatially optimized gene transfection by laser-induced breakdown of optically trapped nanoparticles [PDF]

, 2014
We demonstrate laser-induced breakdown of an optically trapped nanoparticle with a nanosecond laser pulse. Controllable cavitation within a microscope sample was achieved, generating shear stress to monolayers of live cells. This efficiently permeabilize
Arita, Yoshihiko, Campbell, Paul A, Cizmar, Tomas, Dholakia, Kishan, Gunn-Moore, Frank J, Lee, Woei Ming, Torres-Mapa, Maria Leilani   +6 more
core   +1 more source

Effects of the Fluid Replacement Method During Online Hemodiafiltration on the Solute Removal Performance and Biocompatibility Using the Asymmetric Cellulose Triacetate Membrane

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Pre‐dilution online hemodiafiltration (Pre‐HDF) is predominantly used in Japan, whereas post‐dilution online HDF (Post‐HDF) is more common in Europe. An asymmetric cellulose triacetate (ATA) membrane may improve biocompatibility.
Kenji Sakurai, Yoshitaka Kurihara, Fumi Yamauchi, Hiromi Hosoya, Takeshi Saito   +4 more
wiley   +1 more source

Desmoglein‐2 expression is an independent predictor of poor prognosis patients with multiple myeloma

Molecular Oncology, 2022
Multiple myeloma (MM) is the second most common haematological malignancy and is an incurable disease of neoplastic plasma cells (PC). Newly diagnosed MM patients currently undergo lengthy genetic testing to match chromosomal mutations with the most ...
Lisa M. Ebert, Kate Vandyke, M. Zahied Johan, Mark DeNichilo, Lih Y. Tan, Kay K. Myo Min, Benjamin M. Weimann, Brenton W. Ebert, Stuart M. Pitson, Andrew C. W. Zannettino, Craig T. Wallington‐Beddoe, Claudine S. Bonder   +11 more
doaj   +1 more source

Expression of plasma prekallikrein mRNA in human nonhepatic tissues and cell lineages suggests special local functions of the enzyme [PDF]

, 1999
At present it is generally accepted that plasma prekallikrein (PPK) is synthesized in the liver and secreted into the bloodstream. Surprisingly, it has recently been shown that PPK mRNA is present also in RNA from the kidney, adrenal gland and placenta ...
Arnhold, Marianne, Fink, Edwin, Hermann, Andrea, Kresse, Hans, Neth, Peter   +4 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Plasma Corticotropin-Releasing Factor Receptors and B7-2⁺ Extracellular Vesicles in Blood Correlate with Irritable Bowel Syndrome Disease Severity. [PDF]

, 2019
Extracellular vesicles (EVs) are composed of bilayer membranes that are released by different cell types and are present in bodily fluids, such as blood, urine, and bile. EVs are thought to play a key role in intracellular communication.
Bhargava, Aditi, Chang, Lin, Hagiwara, Shin-Ichiro, Hasdemir, Burcu, Heyman, Melvin B   +4 more
core   +1 more source

An adaptive Cartesian embedded boundary approach for fluid simulations of two- and three-dimensional low temperature plasma filaments in complex geometries [PDF]

, 2019
We review a scalable two- and three-dimensional computer code for low-temperature plasma simulations in multi-material complex geometries. Our approach is based on embedded boundary (EB) finite volume discretizations of the minimal fluid-plasma model on ...
Marskar, Robert
core   +2 more sources