Results 31 to 40 of about 1,429,702 (267)
Indian Journal of Dermatology, 2018 Background: Giant basal cell carcinoma (GBCC) is defined as a basal cell carcinoma (BCC) exceeding 5 cm in size. While these tumors impart significant morbidity due to local tissue destruction and have a higher rate of metastatic disease than their ...
J Chase Purnell +3 more
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Hspa13 Promotes Plasma Cell Production and Antibody Secretion
Frontiers in Immunology, 2020 The generation of large numbers of plasma cells (PCs) is a main factor in systemic lupus erythematosus (SLE). We hypothesize that Hspa13, a member of the heat shock protein family, plays a critical role in the control of PC differentiation.
Youdi He +14 more
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Bone Marrow Plasma Cells Modulate Local Myeloid-Lineage Differentiation via IL-10
Frontiers in Immunology, 2019 Bone marrow plasma cells have been reported to represent a major source of IL-10; however, the impact of plasma cell derived IL-10 in that tissue remains poorly understood.
Lingzhang Meng +11 more
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Oncotarget, 2015 As an object for study, the adaptive immune system is proving one of the most compelling and fascinating in the body. This system underlies our primary defence against acute infection and mediates long-term immunity by generation of memory and long-lived effector cells.
Corcoran, LM, Nutt, SL
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Indian Journal of Sexually Transmitted Diseases and AIDS, 2015 Plasma cell vulvitis is a very rare inflammatory disorder of vulva, characterized by a bright-red mucosal lesion of significant chronicity, which may be symptomatic. Very few case studies of this condition are reported in literature. We describe one such classical patient, who presented with slight dyspareunia.
Bharatia, Pravin R. +2 more
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Journal of Applied Hematology, 2015 Plasma cell leukemia (PCL) is defined by the presence of more than 2 × 109/L PCs in the peripheral blood. It is a very rare type of leukemia with poor outcome. In this case, we report a PCL case with peripheral blood morphology of hairy cell leukemia. We
Nahlah Alghasham +3 more
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Blood Reviews, 2011 Plasma cell leukemia (PCL) is a rare, yet aggressive plasma cell (PC) neoplasm, variant of multiple myeloma (MM), characterized by high levels of PCs circulating in the peripheral blood. PCL can either originate de novo (primary PCL) or as a secondary leukemic transformation of MM (secondary PCL). Presenting signs and symptoms are similar to those seen
Flavio, Albarracin, Rafael, Fonseca
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Localized accumulation of kappa restricted Russell body‐containing plasma cells in tonsil
Clinical Case Reports, 2019 An abnormal clonal plasma cell proliferation with Russell bodies is rare in chronic inflammatory reactions in adult patients. We describe the first case of light chain restricted Russell body accumulation within germinal centers of lymphoid follicles of ...
Maryna A. Vazmitsel +2 more
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Type 1 plasminogen deficiency (PLGD‐1) is an ultra‐rare autosomal recessive disorder caused by variants in the PLG gene and affects approximately 1.6 individuals per million. The condition is characterized by decreased plasminogen levels and impaired function, resulting in fibrin‐rich lesions on mucous membranes throughout the body.
Charles Nakar +7 more
wiley +1 more source
Non-Coding RNA, 2022 The differentiation of B cells into antibody secreting plasma cells (PCs) is governed by a strict regulatory network that results in expression of specific transcriptomes along the activation continuum. In vitro models yielding significant numbers of PCs
Renee C. Tschumper +5 more
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