Results 51 to 60 of about 1,564,578 (297)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Chemical equilibration and thermal dilepton production from the quark gluon plasma at finite baryon density [PDF]

, 1999
The chemical equilibration of a highly unsaturated quark-gluon plasma has been studied at finite baryon density. It is found that in the presence of small amount of baryon density, the chemical equilibration for gluon becomes slower and the temperature ...
A. Dumitru, A. Dumitru, A. K. Mohanty, B. Kampfer, C. T. Traxler, D. Dutta, D. K. Srivastava, D. K. Srivastava, E. Shuryak, E. Shuryak, H. Vija, J. Alam, J. D. Bjorken, K. J. Eskola, K. Kumar, L. Xiong, M. Strickland, P. Danielewicz, P. Levai, R. Baier, R. K. Choudhury, S. M. H. Wong, S. M. H. Wong, T. Matsui, T. S. Biro, T. S. Biro, T. S. Biro, X. N. Wang   +27 more
core   +2 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Bridging the Gap Between the Earth's Ionosphere and Plasmasphere

Geophysical Research Letters
Cold plasma distribution in the ionosphere‐plasmasphere system governs wave‐particle interactions, plasma energization and loss, and radio wave propagation.
Artem Smirnov, Yuri Shprits, Hermann Lühr, Elena A. Kronberg, Jerry Goldstein, Yoshizumi Miyoshi, Fabricio Prol, Alessio Pignalberi, Natalia Buzulukova, Nicholas Pedatella, Bernhard Haas, Dedong Wang, Yoshiya Kasahara, Fuminori Tsuchiya, Shoya Matsuda, Atsuki Shinbori, Ayako Matsuoka   +16 more
doaj   +1 more source

Resolving the generation mechanisms and electrodynamical effects of Medium Scale Traveling Ionospheric Disturbances (MSTIDs)

Frontiers in Astronomy and Space Sciences
The term “Medium-Scale Traveling Ionospheric Disturbances” is used to describe a number of different propagating phenomena in ionospheric plasma density with a scale size of hundreds of km.
Jeff Klenzing, Kate Zawdie, Elvira Astafyeva, Anna Belehaki, Meghan Burleigh, Angeline G. Burrell, Cosme A. O. B. Figueiredo, Nathaniel A. Frissell, Weizheng Fu, Dustin Hickey, Joe Huba, Pavel Inchin, Stephen R. Kaeppler, Viswanathan Lakshmi Narayanan, Mani Sivankandan, Jonathon M. Smith, Jonathon M. Smith, Chao Xiong, Tatsuhiro Yokoyama, Matt Zettergren, Shun-Rong Zhang   +20 more
doaj   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Development of Wafer-Type Plasma Monitoring Sensor with Automated Robot Arm Transfer Capability for Two-Dimensional In Situ Processing Plasma Diagnosis

Sensors
In this work, we propose our newly developed wafer-type plasma monitoring sensor based on a floating-type double probe method that can be useful for two-dimensional (2D) in situ plasma diagnosis within a semiconductor processing chamber.
Haewook Park, Juhyun Kim, Sungwon Cho, Kyunghyun Kim, Sungho Jang, Younsok Choi, Hohyun Lee   +6 more
doaj   +1 more source

Fast Collisionless Reconnection Condition and Self-Organization of Solar Coronal Heating

, 2007
I propose that solar coronal heating is a self-regulating process that keeps the coronal plasma roughly marginally collisionless. The self-regulating mechanism is based on the interplay of two effects.
Brown J. C., Bulanov S. V., Dmitri A. Uzdensky, Kulsrud R. M., Landi E., Lee L. C., Masuda S., Parker E. N., Scholer M., Thompson C., Tsuneta S., Ugai M., Uzdensky D. A., Uzdensky D. A.   +13 more
core   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source