Results 41 to 50 of about 197,685 (257)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Bayesian modelling of multiple plasma diagnostics at Wendelstein 7-X

Nuclear Fusion
Inference of electron density and temperature has been performed using multiple, diverse sets of plasma diagnostic data at Wendelstein 7-X. Predictive models for the interferometer, Thomson scattering and helium beam emission spectroscopy (He-BES ...
Sehyun Kwak, U. Hoefel, M. Krychowiak, A. Langenberg, J. Svensson, H. Trimino Mora, Y.-C. Ghim, the W7-X Team   +7 more
doaj   +1 more source

Development of a Set of Synthetic Diagnostics for the Confrontation between 2D Transport Simulations and WEST Tokamak Experimental Data

Applied Sciences, 2022
Transport codes are frequently used for describing fusion plasmas with the aim to prepare tokamak operations. Considering novel codes, such as SolEdge3X-HDG, synthetic diagnostics are a common technique used to validate new models and confront them with ...
Ivan Kudashev, Anna Medvedeva, Manuel Scotto d’Abusco, Nicolas Fedorszak, Stefano Di Genova, Vladislav Neverov, Eric Serre   +6 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Ion acceleration from intense laser-generated plasma: methods, diagnostics and possible applications

Nukleonika, 2015
Many parameters of non-equilibrium plasma generated by high intensity and fast lasers depend on the pulse intensity and the laser wavelength. In conditions favourable for the target normal sheath acceleration (TNSA) regime the ion acceleration from the ...
Torrisi Lorenzo
doaj   +1 more source

The therapeutic opportunities and pitfalls of using iron ion chelators to treat neurodegenerative diseases

FEBS Letters, EarlyView.
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley   +1 more source

Cross Sections for Electron Impact Excitation of O VI Lines

Open Astronomy, 2011
Radiative atomic data and electron impact excitation cross sections for the 2s-2p transitions in O VI for transitions among the fine structure levels belonging to the 1s2nl (2 ≤ n ≤ 5) configurations have been calculated.
Elabidi Haykel, Sahal-Bréchot Sylvie, Nessib Nébil Ben   +2 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source