Results 51 to 60 of about 214,036 (307)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Detection of trace heavy metals using atmospheric pressure glow discharge by optical emission spectra

High Voltage, 2019
In this Letter, atmospheric pressure glow discharge based on a small discharge gap is excited by sine AC voltage in air on purpose of detecting trace heavy metal elements in solid samples, which makes the detection limits of trace heavy metal elements ...
Xiao Li, De-Zheng Yang, Hao Yuan, Jian-Ping Liang, Tao Xu, Zi-Lu Zhao, Xiong-Feng Zhou, Li Zhang, Wen-Chun Wang   +8 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Temporal distribution of linear densities of the plasma column in a plasma focus discharge

Nukleonika, 2015
Experiments were carried out on the PF-1000 plasma focus device, with a deuterium filling and with deuterium puffing from a gas-puff nozzle placed on the axis of the anode face. The current was reaching 2 MA.
Cikhardtova Balzhima, Kubeš Pavel, Cikhardt Jakub, Paduch Marian, Zielinska Ewa, Kravárik Josef, Řezáč Karel, Kortanek Jiři, Šíla Ondřej   +8 more
doaj   +1 more source

Plasma Scalpels: Devices, Diagnostics, and Applications

Biomedicines, 2022
The plasma scalpel is an application of gas discharges in electrosurgery. This paper introduces the device structure and physicochemical parameters of the two types of plasma scalpels, namely, a single-electrode Ar discharge device (argon plasma ...
Ao Xiao, Dawei Liu, Dongcheng He, Xinpei Lu, Kostya (Ken) Ostrikov   +4 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Advanced plasma diagnostics for thin-film deposition [PDF]

, 2008
An ever-increasing amount of diagnostics is available to study plasma and obtain quantities lIke atomic and molecular densities, ion and electron densities, tempera­ture ofelectronsandheavyparticles, andtheirvelocities, to justnamea few. But also surface
Kawai, Y., Schram, D.C., Engeln, R.A.H., Sanden, van de, M.C.M., Favia, P., Creatore, M., Kessels, W.M.M., Agostino, d', R.   +7 more
core  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Bayesian modelling of multiple plasma diagnostics at Wendelstein 7-X

Nuclear Fusion
Inference of electron density and temperature has been performed using multiple, diverse sets of plasma diagnostic data at Wendelstein 7-X. Predictive models for the interferometer, Thomson scattering and helium beam emission spectroscopy (He-BES ...
Sehyun Kwak, U. Hoefel, M. Krychowiak, A. Langenberg, J. Svensson, H. Trimino Mora, Y.-C. Ghim, the W7-X Team   +7 more
doaj   +1 more source

Ion acceleration from intense laser-generated plasma: methods, diagnostics and possible applications

Nukleonika, 2015
Many parameters of non-equilibrium plasma generated by high intensity and fast lasers depend on the pulse intensity and the laser wavelength. In conditions favourable for the target normal sheath acceleration (TNSA) regime the ion acceleration from the ...
Torrisi Lorenzo
doaj   +1 more source