Results 71 to 80 of about 410,850 (322)

The Early Diagnostic Dilemma in Angioimmunoblastic T Cell Lymphoma with Excessive Plasma Cells Proliferation [PDF]

, 2021
Chunyan Wang, Xia Mao, Songya Liu, He Cheng, Ying Wang, Li Zhu, Yangyang Wang, Yicheng Zhang   +7 more
openalex   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Plasma diagnostics of an EIT wave observed by Hinode/EIS and SDO/AIA

, 2011
We present plasma diagnostics of an EIT wave observed with high cadence in Hinode/EIS sit-and-stare spectroscopy and SDO/AIA imagery obtained during the HOP-180 observing campaign on 2011 February 16.
Asai, Attrill, Chen, Chen, Cohen, Downs, Harra, Harra, Kienreich, Kienreich, Kozarev, Lemen, Liu, Ma, Muhr, Patsourakos, Thompson, Veronig, Veronig, Veronig   +19 more
core   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Diagnosing the Source Region of a Solar Burst on 26 September 2011 by Microwave Type III Pairs [PDF]

, 2016
This work reports a peculiar and interesting train of microwave type III pair bursts in the impulsive rising phase of a solar flare on 2011 September 26. The observations include radio spectrometers at frequency of 0.80 - 2.00 GHz, hard X-ray (RHESSI and
Huang, Jing, Karlicky, Marian, Kashapova, Larisa, Kontar, Eduard P., Meszarosova, Hana, Tan, Baolin, Yan, Yan   +6 more
core   +2 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

X-ray Line Diagnostics of Hot Accretion Flows around Black Holes [PDF]

, 2000
We compute X-ray emission lines from thermal plasma in hot accretion flows. We show that line profiles are strong probes of the gas dynamics, and we present line-ratio diagnostics which are sensitive to the distribution of mass with temperature in the ...
Bely-Daubau F., Dubau J., John Raymond, Mewe R., Ramesh Narayan, Reynolds C. S., Rosalba Perna   +6 more
core   +3 more sources

Evaluation of NVIDIA Xavier NX Platform for Real-Time Image Processing for Plasma Diagnostics [PDF]

, 2022
Bartłomiej Jabłoński, Dariusz Makowski, Piotr Perek, Patryk Nowak vel Nowakowski, A. Puig Sitjes, M. Jakubowski, Yu Gao, A. Winter, The W-X Team   +8 more
openalex   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

SUMMA hot-ion plasma heating research at NASA Lewis Research Center [PDF]

The SUMMA superconducting magnetic mirror facility and the associated hot-ion plasma research were described. SUMMA is characterized by intense magnetic fields and a large-diameter working bore (41 cm diameter) with room-temperature access.
Lauver, M. R., Patch, R. W., Reinmann, J. J.   +2 more
core   +1 more source