Results 101 to 110 of about 4,773,777 (394)

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Outcome in Severe Guillain-Barre Syndrome

Pediatric Neurology Briefs, 1999
The effect of various therapies on duration of illness in children with severe Guillain-Barre syndrome (GBS) was evaluated at CHMC, Seattle, WA.
J Gordon Millichap
doaj   +1 more source

Polarized Negative Ion Source with Multiply Sphericaly Focusing Surface Plasma Ionizer

, 2018
It is proposed one universal H-/D- ion source design combining the most advanced developments in the field of polarized ion sources to provide high-current high-brightness ion beams with >90% polarization and improved lifetime, reliability, and power ...
Dudnikov, A., Dudnikov, V.
core   +1 more source

Patatin‐domain‐containing (phospho)lipases under control: Mammalian co‐regulators and pathogenic activation mechanisms

FEBS Open Bio, EarlyView.
Patatin domain‐containing (phospho)lipases are lipid‐hydrolyzing enzymes central to metabolism, membrane remodeling, and signaling. Their activity relies on precise co‐activation mechanisms involving protein–protein interactions and conformational rearrangements.
Noopur Dubey, Lina Riegler‐Berket, Monika Oberer   +2 more
wiley   +1 more source

Plasmapheresis in the treatment of fatty liver of pregnancy: A case report

Nursing Practice Today, 2019
Introduction: Acute fatty liver of pregnancy (AFLP) is a rare but lethal disease with liver involvement that appears in the third trimester of pregnancy. There is no specific treatment for AFLP.
Tahereh Ashrafganjoei, Soha Mirreza, Mitra Eftekhariyazdi, Forough Mortazavi   +3 more
doaj   +1 more source

Severe complications in a 25‐year‐old male after brown recluse spider bite treated by therapeutic plasma exchange: A case report and review of other case studies [PDF]

, 2023
Sarah Cain, Frederick V Plapp, Amitava Dasgupta, Zhan Ye   +3 more
openalex   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

An Attempted Suicide with Copper Sulphate injected intravenously:Pathopsysiology and Therapy about a case report [PDF]

, 2017
Acute copper sulphate poisoning is an unusual event, rarely following parenteral exposure, complicated by toxicological effects as haemolytic anaemia, methaemoglobinaemia , hepato-renal damage and acute rhabdomyolysis.
Baldini, Enrico, Garramone, Alessia, Grassi, Maria Caterina, Lombardi, Laura, Lonati, Davide, Spagnolello, Ornella, Staltari, Orietta   +6 more
core  

A Review of Recent Developments in Atomic Processes for Divertors and Edge Plasmas

, 1995
The most promising concepts for power and particle control in tokamaks and other fusion experiments rely upon atomic processes to transfer the power and momentum from the edge plasma to the plasma chamber walls. This places a new emphasis on processes at
Afrosimov, Akiba, Allen, Anders, Bacal, Bachmann, Badnell, Badnell, Barnett, Bates, Bell, Bitter, Bonnin, Botero, Burgess, Cacciatore, Clark, D.E. Post, Djuric, Dolder, Dunn, Ehrhardt, Fonck, Grossman, Haas, Harrision, Herrman, Hiskes, Hiskes, Hogan, Hogan, Hulse, Hulse, Hulse, Hutchinson, Isler, Ito, Janeschitz, Janeschitz, Janev, Janev, Janev, Jensen, Jensen, Kato, Klepper, Krasheninnikov, Lackner, Lengyel, Lotz, Mahdavi, Marchand, Nagami, Neuhauser, Ogden, Petravic, Petrie, Petrie, Phaneuf, Phaneuf, Pindzola, Pindzola, Poschenrieder, Post, Post, Post, Rebut, Rebut, Reiter, Roth, Roth, Ruzic, Scott, Shimada, Stangeby, Summers, Tawara, Tawara, v. Emmichoven, v. Hellerman, Wahlin, Wan, Watkins, Weisheit, Wiese, Wiese, Wolf   +86 more
core   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source