Results 91 to 100 of about 390,876 (339)

Alterations in plasma lipid profile patterns in oral cancer

open access: yesJournal of Indian Academy of Oral Medicine and Radiology, 2014
Aims and Objectives: The aim of this study was to evaluate and compare the alterations in the plasma lipid profile patterns in oral cancer patients and controls.
Mahesh Neerupakam   +5 more
doaj   +1 more source

Delivery of human apolipoprotein (apo) E to liver by an [E1(-), E3(-), polymerase(-), pTP(-)] adenovirus vector containing a liver-specific promoter inhibits atherogenesis in immunocompetent apoE-deficient mice [PDF]

open access: yes, 2006
Recombinant adenovirus (rAd)-mediated apoE gene transfer to the liver of apoE(-/-) mice is anti-atherogenic. However, first generation rAd vectors were associated with immune clearance of transduced hepatocytes, while an improved [E1(-), E3(-) polymerase(
Amalfitano, A   +4 more
core  

Gene-environment interactions due to quantile-specific heritability of triglyceride and VLDL concentrations. [PDF]

open access: yes, 2020
"Quantile-dependent expressivity" is a dependence of genetic effects on whether the phenotype (e.g., triglycerides) is high or low relative to its distribution in the population.
Williams, Paul T
core   +1 more source

Relationship between Sustained Reductions in Plasma Lipid and Lipoprotein Concentrations with Apheresis and Plasma Levels and mRNA Expression of PTX3 and Plasma Levels of hsCRP in Patients with HyperLp(a)lipoproteinemia [PDF]

open access: yes, 2016
The effect of lipoprotein apheresis (Direct Adsorption of Lipids, DALI) (LA) on plasma levels of pentraxin 3 (PTX3), an inflammatory marker that reflects coronary plaque vulnerability, and expression of PTX3 mRNA was evaluated in patients with hyperLp(a ...
De Nève, Joel   +6 more
core   +3 more sources

Potent Liver‐Tropic mRNA Lipid Nanoparticles: ApoE‐Mediated Delivery Through a Low‐Density Lipoprotein Receptor Independent Uptake Mechanism

open access: yesAdvanced Materials, EarlyView.
Helper and ionizable lipids play a crucial role in determining ApoE binding and subsequent liver tropism and LDLR‐mediated uptake. Ionizable lipids primarily govern the LDLR‐independent uptake pathway. This complementary interplay between lipid components ultimately governs LNP delivery performance and therapeutic efficacy in the liver.
Ashish Sarode   +16 more
wiley   +1 more source

Hydrolysis of chylomicron arachidonate and linoleate ester bonds by lipoprotein lipase and hepatic lipase

open access: yesJournal of Lipid Research, 1987
Chylomicrons labeled with [3H]arachidonic and [14C]linoleic acid were incubated with bovine milk lipoprotein lipase or rat postheparin plasma, containing both lipoprotein lipase and hepatic lipase.
A Nilsson, B Landin, M C Schotz
doaj   +1 more source

Lipopolysaccharide (LPS)-binding protein is carried on lipoproteins and acts as a cofactor in the neutralization of LPS. [PDF]

open access: yes, 1994
Lipoproteins isolated from normal human plasma can bind and neutralize bacterial lipopolysaccharide (LPS) and may represent an important mechanism in host defense against gram-negative septic shock. Recent studies have shown that experimentally elevating
Kane, JP   +4 more
core   +1 more source

Correlative Super‐Resolution Imaging of Cellular Nanopores Facilitated by Transparent Polymer Waveguide Chips

open access: yesAdvanced Optical Materials, Volume 13, Issue 8, March 13, 2025.
Correlative super‐resolution optical imaging of the ultrastructure of rat liver sinusoidal endothelial cells (LSECs) across a large field of view (FOV) with 3D structured illumination microscopy (3D‐SIM) and single‐molecule localization microscopy (SMLM), facilitated by a transparent polymer photonic waveguide chip, is presented.
Surjendu Bikash Dutta   +9 more
wiley   +1 more source

Serum lipid profiles in acute myocardial infarction patients in Gorgan [PDF]

open access: yes, 2012
Acute myocardial infarction is one of the important reasons of death and unhealthiness in the world. The present study was undertaken to investigate the changes in serum lipids and lipoproteins in patients with acute myocardial infarction. This study was
Marjani, A., Shirafkan, A., Zaker, F.
core  

An integrated mathematical model of cellular cholesterol biosynthesis and lipoprotein metabolism [PDF]

open access: yes, 2018
Cholesterol regulation is an important aspect of human health. In this work we bring together and extend two recent mathematical models describing cholesterol biosynthesis and lipoprotein endocytosis to create an integrated model of lipoprotein ...
Pool, Frances   +2 more
core   +2 more sources

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