A Simple Fluorescent Cholesterol Labeling Method to Cryoprotect and Detect Plasma Lipoprotein-X. [PDF]
Neufeld EB +6 more
europepmc +1 more source
To distinguish how Salmonella invades cells vs how it survives long‐term, a parallel CRISPR screening platform is developed. This approach reveals the host proteins that the bacterium exploits at different stages of infection. The study identifies SORL1 as a novel host factor for invasion and demonstrates that blocking it with an antibody effectively ...
Sehee Yun +6 more
wiley +1 more source
Plasma Lipoprotein(a) Levels as Determinants of Arterial Stiffening in Hypertension. [PDF]
Brosolo G +8 more
europepmc +1 more source
Obesity involves chronic inflammation and mitochondrial dysfunction. This study identifies cytochrome P450 2E1 (CYP2E1) as a novel inflammatory target in adipose tissue. Its activity increases in obese mice and correlates with inflammation and mitochondrial impairment.
Jinhuan Qiu +10 more
wiley +1 more source
Plasma lipoprotein (a) and tissue plasminogen activator are associated with increased risk of atherosclerotic cardiovascular disease. [PDF]
Mayyas F, Bani Omar E.
europepmc +1 more source
Role of the low density lipoprotein receptor in the flux of cholesterol through the plasma and across the tissues of the mouse. [PDF]
Yasunori Osono +3 more
openalex +1 more source
A Novel 10‐Protein Score for Liver Fat Content Predicts Cardiovascular‐Kidney‐Metabolic Disease Risk
A novel 10‐protein plasma score precisely quantifies liver fat, outperforming the fatty liver index. It robustly predicts the risk of numerous cardiovascular‐kidney‐metabolic diseases and integrates with genetic data for precision prevention, offering a practical alternative to magnetic resonance imaging (MRI). Abstract Liver fat content (LFC) is a key
Xiaoqin Gan +12 more
wiley +1 more source
Differences in plasma lipoprotein profiles between patients with chronic peripheral neuropathic pain and healthy controls: an exploratory pilot study. [PDF]
Jönsson M +4 more
europepmc +1 more source
Hepatic Deficiency of Low Density Lipoprotein Receptor-related Protein-1 Reduces High Density Lipoprotein Secretion and Plasma Levels in Mice [PDF]
Joshua E. Basford +6 more
openalex +1 more source
This study presents an impedance‐based single‐cell profiling platform that quantifies the electrical and mechanical properties of neutrophils across in vitro, in vivo, and clinical samples. The approach reveals distinct biophysical alterations associated with type 2 diabetes (T2DM) and cardiovascular complications, suggesting its potential utility for ...
Linwei He +13 more
wiley +1 more source

