Results 231 to 240 of about 2,752,610 (400)
ChemMedChem, EarlyView.Several derivatives incorporating five‐membered aromatic rings are described in this review as bile acid receptor modulators, particularly targeting the farnesoid X receptor and the G protein‐coupled bile acid receptor 1. This review provides a comprehensive analysis of patents and literature that is useful to support researchers in the design of new ...
Claudia Finamore +5 more
wiley +1 more source
The use of cholesterol-4-C14-labeled lipoproteins as a tracer for plasma cholesterol in the dog
, 1961 Daniel Porte, Richard J. Havel
openalex +1 more source
Separation of Plasma Lipoproteins
Journal of Atherosclerosis and Thrombosis, 2006 openaire +3 more sources
Harnessing Viral Proteases for Cellular and Molecular Engineering
Chemistry–Methods, EarlyView.Engineered viral proteases (VIPs) provide programmable control of protein function with high specificity and low toxicity. Integrated with chemogenetic and optogenetic modules, these VIP systems enable logic gate manipulation for targeted regulation of cell signaling, gene expression, protein secretion, and degradation, thereby offering versatile ...
Mingguang Cui +2 more
wiley +1 more source
The regulation of plasma lipoprotein concentrations as affected in human mutants.
, 1969 Donald S. Fredrickson
openalex +1 more source
Protein deglycosylation can drastically affect the cellular uptake [PDF]
, 2019 Ghazaryan, A. +2 more
core +2 more sources
Model‐Informed Drug Development Applications and Opportunities in mRNA‐LNP Therapeutics
Clinical Pharmacology &Therapeutics, EarlyView.The utilization of lipid nanoparticles (LNP) for encapsulating mRNA has revolutionized the field of therapeutics, enabling the rapid development of COVID‐19 vaccines and cancer vaccines. However, the clinical development of mRNA‐LNP therapeutics faces numerous challenges due to their complex mechanisms of action and limited clinical experience.
Jiawei Zhou +6 more
wiley +1 more source
Plasma Levels of Major Lipoproteins and Yolk Deposition in the Ovary
, 1960 Kazutaka HOMMA, Shunzo KATOH, Jiro Gotoh
openalex +2 more sources