Results 21 to 30 of about 2,752,610 (400)

Effect of a novel nutraceutical combination on serum lipoprotein functional profile and circulating PCSK9 [PDF]

, 2017
BACKGROUND: A beneficial effect on cardiovascular risk may be obtained by improving lipid-related serum lipoprotein functions such as high-density lipoproteins (HDLs) cholesterol efflux capacity (CEC) and serum cholesterol loading capacity (CLC) and by ...
Adorni, Maria Pia, Bernini, Franco, Ferri, Nicola, Izzo, Raffaele, Marchiano, Silvia, Rozza, Francesco, Trimarco, Valentina, Zimetti, Francesca   +7 more
core   +3 more sources

Human prions and plasma lipoproteins [PDF]

Proceedings of the National Academy of Sciences, 2006
Prions are composed solely of an alternatively folded isoform of the prion protein (PrP), designated PrP Sc . The polyoxometalate phosphotungstic acid has been used to separate PrP Sc from its precursor PrP C by selective precipitation; notably, native PrP ...
SAFAR JG, WILLE H, GESCHWIND MD, DEERING C, LATAWIEC D, SERBAN A, KING DJ, Legname, Giuseppe, WEISGRABER KH, MAHLEY RW, MILLER BL, DEARMOND SJ, PRUSINER SB   +12 more
openaire   +3 more sources

Change of plasma lipoproteins by heparin-released lipoprotein lipase [PDF]

Experimental & Molecular Medicine, 1999
Lipoprotein lipase (LPL) is known to be attached to the luminal surface of vascular endothelial cells in a complex with membrane-bound heparan sulfate, and released into blood stream by heparin. LPL that catalyzes hydrolysis of triglyceride (TGL) on chylomicron and VLDL into two fatty acids and monoacylglycerol, is also implicated to participate in an ...
Bon-Sun Koo, Tae-Keun Kim, Jin-Woo Park, Byung-Hyun Park, Jeong-Yeh Yang   +4 more
openaire   +3 more sources

HDL Phospholipids, but Not Cholesterol Distinguish Acute Coronary Syndrome From Stable Coronary Artery Disease

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background Although acute coronary syndromes (ACS) are a major cause of morbidity and mortality, relationships with biologically active lipid species potentially associated with plaque disruption/erosion in the context of their lipoprotein carriers are ...
Peter J. Meikle, Melissa F. Formosa, Natalie A. Mellett, Kaushala S. Jayawardana, Corey Giles, David A. Bertovic, Garry L. Jennings, Wayne Childs, Medini Reddy, Andrew L. Carey, Arul Baradi, Shane Nanayakkara, Andrew M. Wilson, Stephen J. Duffy, Bronwyn A. Kingwell   +14 more
doaj   +1 more source

Moderate exercise increases affinity of large very low density lipoproteins for hydrolysis by lipoprotein lipase [PDF]

, 2015
Context: Postprandial triglyceride (TG) concentration is independently associated with cardiovascular disease risk. Exercise reduces postprandial TG concentrations but the mechanisms responsible are unclear.
Bedford, Dorothy K., Caslake, Muriel J., Cooney, Josephine, GHAFOURI, Khloud, Gill, Jason M.R., Wilson, John   +5 more
core   +1 more source

Apolipoprotein(a) gene accounts for greater than 90% of the variation in plasma lipoprotein(a) concentrations.

Journal of Clinical Investigation, 1992
Plasma lipoprotein(a) [Lp(a)], a low density lipoprotein particle with an attached apolipoprotein(a) [apo(a)], varies widely in concentration between individuals.
E. Boerwinkle, Carla C. Leffert, Jingping Lin, Carolin Lackner, Giulia Chiesa, H. Hobbs   +5 more
semanticscholar   +1 more source

Lipolysis generates platelet dysfunction after in vivo heparin administration [PDF]

, 2002
Heparin, when administered to patients undergoing operations using cardiopulmonary bypass, induces plasma changes that gradually impair platelet macroaggregation, but heparinization of whole blood in vitro does not have this effect.
Belcher, P.R., Caslake, M.J., Chaudhry, M.A., Day, S., Muriithi, E.W., Wheatley, D.J.   +5 more
core   +1 more source

Genetic variants, plasma lipoprotein(a) levels, and risk of cardiovascular morbidity and mortality among two prospective cohorts of type 2 diabetes.

European Heart Journal, 2012
AIMS To examine the relations between genetic loci, plasma lipoprotein(a) [Lp(a)] levels, and cardiovascular disease (CVD) risk among diabetic patients and compare with the observations in the general population.
Q. Qi, T. Workalemahu, Cuilin Zhang, F. Hu, L. Qi   +4 more
semanticscholar   +1 more source

Liver Transplantation to Provide Low-Density-Lipoprotein Receptors and Lower Plasma Cholesterol in a Child with Homozygous Familial Hypercholesterolemia [PDF]

, 1984
A six-year-old girl with severe hypercholesterolemia and atherosclerosis had two defective genes at the low-density-lipoprotein (LDL) receptor locus, as determined by biochemical studies of cultured fibroblasts.
Cummings, David W. Bilheimer, Goldstein, Joseph L. Goldstein, Michael S. Brown, Pittman, Schneider, Schneider, Scott M. Grundy, Thomas E. Starzl   +9 more
core   +1 more source

Peroxisome Proliferator Activated Receptors and Lipoprotein Metabolism

PPAR Research, 2008
Plasma lipoproteins are responsible for carrying triglycerides and cholesterol in the blood and ensuring their delivery to target organs. Regulation of lipoprotein metabolism takes place at numerous levels including via changes in gene transcription.
Sander Kersten
doaj   +1 more source