Results 71 to 80 of about 390,876 (339)

Striated muscle gene therapy for the treatment of lipoprotein lipase deficiency. [PDF]

PLoS ONE, 2018
Excessive circulating triglycerides due to reduction or loss of lipoprotein lipase activity contribute to hypertriglyceridemia and increased risk for pancreatitis.
Katherine E Gadek, Hong Wang, Monica N Hall, Mitchell Sungello, Andrew Libby, Drew MacLaskey, Robert H Eckel, Bradley B Olwin   +7 more
doaj   +1 more source

Oral Dosed Organo‐Silica Nanoparticles Restore Glucose Homeostasis and β‐Cell Function in Diabetes Rats

Advanced Functional Materials, EarlyView.
An oral nanoplatform, MOP@T@D, which can maintain glucose homeostasis and restore islet β cells in diabetic rats is developed. It achieves efficient intestinal absorption and liver‐targeted delivery. The nanoparticle disintegrates only in response to hyperglycemia to release insulin on demand and provides antioxidant protection through selenoprotein ...
Chenxiao Chu, Mingli Wei, Che Bian, Xiaoshuang Bi, Yaxin Deng, Peifu Xiao, Jiansong Zhao, Yuying Wang, Haibing He, Jingxin Gou, Tian Yin, Xing Tang, Li Yang, Hongbo Zhang, Yu Zhang   +14 more
wiley   +1 more source

Hyperlipoproteinemia in Nagase analbuminemic rats: effects of pravastatin on plasma (apo)lipoproteins and lecithin:cholesterol acyltransferase activity.

Journal of Lipid Research, 1991
The present study demonstrates very high levels of plasma lipids and high density lipoprotein (HDL) apolipoproteins (apoA-I and apoE) in female Nagase analbuminemic rats (NAR) fed a semi-synthetic diet in order to further increase the hyperlipidemia ...
A Van Tol, EH Jansen, HA Koomans, JA Joles   +3 more
doaj   +1 more source

Relationship Between Physical Conditioning and Plasma High Density Lipoprotein-Cholesterol Concentration [PDF]

, 1983
Five subjects (three females and two males) took part in an exercise regimen in order to determine if aerobic exercise results in an increase in high-density lipoprotein-cholesterol levels (HDL-C) in the plasma.
Baeyens, Dennis A., Morgans, Leland F., Morris, Manford D.   +2 more
core   +2 more sources

High plasma leptin levels confer increased risk of atherosclerosis in women with systemic lupus erythematosus, and are associated with inflammatory oxidised lipids. [PDF]

, 2011
BackgroundPatients with systemic lupus erythematosus (SLE) are at increased risk of atherosclerosis, even after accounting for traditional risk factors.
Charles-Schoeman, Christina, Chernishof, Marissa, FitzGerald, John, Gorn, Alan, Grossman, Jennifer, Hahn, Bevra H, La Cava, Antonio, McMahon, Maureen, Ragavendra, Nagesh, Sahakian, Lori, Skaggs, Brian J, Wallace, Daniel J, Weisman, Michael, Witztum, Joseph L, Wong, Weng Kee   +14 more
core   +2 more sources

Generation of an Induced Pluripotent Stem Cell‐Derived Alveolar Type II In Vitro Model to Study Influenza A Virus Infection and Drug Treatments

Advanced Healthcare Materials, EarlyView.
Patient‐specific induced pluripotent stem cells (iPSCs) can be differentiated into alveolar type II cells (iAT2s), expanded as 3D alveolospheres, and grown at physiologically relevant air–liquid interface (ALI). This study shows for the first time the infectability of iAT2s by the influenza A virus (IAV) and proves their responsiveness to the well ...
Lena Gauthier, Hristina Koceva, Yann Bachelot, Rosanne W. Koutstaal, Puck B. van Kasteren, Marc Thilo Figge, Christian Eggeling, Alexander Sandy Mosig   +7 more
wiley   +1 more source

Study on the correlation between the concentration of plasma lipoprotein-associated phospholipase A2 and coronary heart disease

Chronic Diseases and Translational Medicine, 2015
Objective: This study explores the correlation between plasma lipoprotein-associated phospholipase A2 (Lp-PLA2) and coronary heart disease (CHD) by comparing the level of plasma Lp-PLA2 in the plasma of patients with different types of CHD.
Jin-Ming Cen, Jie Cheng, Qing-Yuan Xiong, Bai-Qiang Mei, Wei-Biao Cai, Xi-Li Yang   +5 more
doaj   +1 more source

Identification of fibrin clot-bound plasma proteins. [PDF]

PLoS ONE, 2012
Several proteins are known to bind to a fibrin network and to change clot properties or function. In this study we aimed to get an overview of fibrin clot-bound plasma proteins.
Simone Talens, Frank W G Leebeek, Jeroen A A Demmers, Dingeman C Rijken   +3 more
doaj   +1 more source

Association between skeletal muscle mass and serum concentrations of lipoprotein lipase, GPIHBP1, and hepatic triglyceride lipase in young Japanese men [PDF]

, 2019
学位記番号 ...
Matsumoto, Ryutaro, マツモト, リュウタロウ, 松本, 隆太郎   +2 more
core  

A simple method to assess the oxidative susceptibility of low density lipoproteins [PDF]

, 2001
BACKGROUND: Oxidative modification of low density lipoproteins (LDL) is recognized as one of the major processes involved in atherogenesis. The in vitro standardized measurement of LDL oxidative susceptibility could thus be of clinical significance.
A Lavy, B Guerci, B Wallin, C Coudray, CJ Schwartz, D Steinberg, D Steinbergt, H Esterbauer, H Esterbauer, H Ohkawa, JA Buege, JM Brun, M El-Saadani, M Taus, MA Moss, MAQ Arshad, MM Bradford, N Rifai, PN Demacker, TJ Lyons   +19 more
core   +4 more sources