Results 101 to 110 of about 6,324,510 (249)

Mutual interactions between aquaporins and membrane components

Frontiers in Plant Science, 2016
During the last years, a number of studies have been focused on the structural evaluation of protein complexes in order to get mechanistic insights into how proteins communicate at the molecular level within the cell.
MCarmen Martinez-Ballesta, Micaela Carvajal   +1 more
doaj   +1 more source

Anti‐Inflammatory and Neuroactive Effects of Polymer‐Coated Iron Oxide Nanoparticles Functionalized With Interleukin 4 for Spinal Cord Injury

Advanced Healthcare Materials, EarlyView.
Polymer‐coated IONPs functionalized with IL‐4 display respective neuroactive and anti‐inflammatory actions on neural progenitor cells and macrophages/microglia in vitro. When examined chronically in a rat experimental model of spinal cord injury, rGO scaffolds carrying these nanosystems adequately integrate into the lesion, significantly reduce ...
Julia Martínez‐Ramírez, Paloma Lozano‐Picazo, María de Lamo‐Atencia, Andrea Ferreras, Esther Benayas‐Martín, Elena Fernández‐López, Marina Sánchez‐Petidier, Verónica Barranco‐Maresca, Víctor Caz, Anne des Rieux, Juliana M. Rosa, María del Puerto Morales, María C. Serrano   +12 more
wiley   +1 more source

Cholecystokinin 1 Receptor – A Unique G Protein-Coupled Receptor Activated by Singlet Oxygen (GPCR-ABSO)

Frontiers in Physiology, 2018
Plasma membrane-delimited generation of singlet oxygen by photodynamic action with photosensitizer sulfonated aluminum phthalocyanine (SALPC) activates cholecystokinin 1 receptor (CCK1R) in pancreatic acini.
Hong Ning Jiang, Yuan Li, Wen Yi Jiang, Zong Jie Cui   +3 more
doaj   +1 more source

Hybrid Biofabrication of a Hierarchically Organized Periosteum‐Inspired In Vitro Platform

Advanced Healthcare Materials, EarlyView.
A hybrid biofabrication strategy integrates melt electrowriting with extrusion‐based 3D bioprinting to create a hierarchically organized periosteum‐inspired in vitro platform. Spatially defined osteogenic, fibrous, and endothelial cell‐containing compartments support long‐term culture, osteogenic maturation, and CD31+ endothelial cell organization ...
Yakui Liu, Xinggui Tian, Anne Bernhardt, Anja Lode, Max von Witzleben, Ege Kirbas, Stefan Zwingenberger, Michael Gelinsky   +7 more
wiley   +1 more source

Magnetoactive Hydrogels to Probe Curvature‐Directed Endothelial Cell Mechanosensing

Advanced Healthcare Materials, EarlyView.
This work establishes a platform to investigate local curvature as a regulator of endothelial mechanosensing independent of shear stress. Magnetoactive hydrogels enable on‐demand curvature of endothelial monolayers to reproduce tortuosity quantified by clinically established metrics.
Avinava Roy, Grace K. Hinds, Joshua Yu‐Chung Liu, Ziqian Yang, Rishab Yanala, Arina E. Velieva, Claudia Loebel   +6 more
wiley   +1 more source

A cytosolic factor mediating membrane recruitment of AP-1 clathrin adaptors [PDF]

, 2008
Transport of cargo within the endocytic and secretory pathway is generally mediated by coated vesicles. These vesicles are formed through the recruitment of cytosolic coat proteins to the donor membrane that act as a scaffold to form coated buds and ...
Suri, Gregor
core   +1 more source

Leaftronics: Bio‐Fractal Scaffolds From Leaf Venation for Low‐Waste Electronics

Advanced Materials, EarlyView.
“Leaftronics” transforms naturally evolved leaf venation into quasi‐fractal scaffolds for sustainable electronics. Polymer‐infiltrated leaf skeletons can be used to fabricate ultra‐smooth, reflow‐ and thin‐film‐compatible decomposable substrates, while making the same lignocellulose networks conducting results in flexible transparent electrodes.
Rakesh Rajendran Nair, Hrisheekesh Thachoth Chandran, Karl Leo, Hans Kleemann   +3 more
wiley   +1 more source

Toxic effects of Helix aspersa snail egg hydrolyzates obtained by static in vitro digestion on Caco-2 colorectal adenocarcinoma cells

Scientific Reports
Colorectal cancer is the third most common cancer. Anticancer compounds obtained after the digestion of snail eggs may hurt the growth and development of colon cancer cells.
Magdalena Matusiewicz, Joanna Kuczka, Michalina Danił, Klara Piotrowska, Hanna Antushevich, Tomasz Niemiec   +5 more
doaj   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Charge‐Reversed Lipid Nanoparticles Enable Encapsulation of Pt2L4 Nanocages for In vivo Anti‐Cancer Treatment

Advanced Materials, EarlyView.
Charge‐reversed lipid nanoparticles (revLNPs) enable efficient encapsulation and delivery of cationic Pt2L4 nanocages. Encapsulation preserves potent anticancer activity while improving circulation, reducing vascular leakage, and promoting favorable biodistribution in vivo.
Renzo A. Knol, Bochuan Hu, Eduard O. Bobylev, Martina Farber, Petrus C. M. Laan, Thomas J. F. Kock, Bauke Fontein, Johanna Erbani, Oscar Escalona‐Rayo, Seline S. Roose, Tom Keijer, Gabriel Forn‐Cuní, B. Ewa Snaar‐Jagalska, Leila Akkari, Joost N. H. Reek, Alexander Kros, Dennis Aschmann   +16 more
wiley   +1 more source