Results 41 to 50 of about 391,649 (370)

Severe loss-of-function mutations in the adrenocorticotropin receptor (ACTHR, MC2R) can be found in patients diagnosed with salt-losing adrenal hypoplasia [PDF]

, 2006
Objective: Familial glucocorticoid deficiency type I (FGD1) is a rare form of primary adrenal insufficiency resulting from recessive mutations in the ACTH receptor (MC2R, MC2R).
Achermann, JC, Al-Ali, M, Alzyoud, M, Brain, CE, Clark, AJ, Dattani, MT, Hindmarsh, PC, Lin, L, Metherell, LA   +8 more
core   +2 more sources

Secondary Hypertension due to a Renin-secreting Juxtaglomerular Cell Tumor

Journal of the Formosan Medical Association, 2010
A juxtaglomerular cell tumor (JCT) is a rare, renin-secreting tumor of the kidney and can cause hypertension. JCT is pathologically benign, and resection of the tumor is curative for hypertension.
Shih-Yi Lin, Wayne-Young Liu, Wen-Chi Chen, Rong-Hsing Chen   +3 more
doaj   +1 more source

Postural augmentation of plasma renin activity and aldosterone excretion in normal people.

Journal of Clinical Investigation, 1967
Peripheral plasma renin activity and aldosterone excretion rates have been measured in normal people during recumbency, recumbent exercise, tilting, and continuous ambulation. Upright posture induces a prompt elevation in peripheral plasma renin activity
E. Cohen, J. Conn, D. Rovner
semanticscholar   +1 more source

Ornipressin in the treatment of functional renal failure in decompensated liver cirrhosis [PDF]

, 1991
In 11 patients with decompensated cirrhosis and deteriorating renal function, the effect of the vasoconstrictor substance 8-ornithin vasopressin (ornipressin; POR 8; Sandoz, Basel, Switzerland) on renal function, hemodynamic parameters, and humoral ...
Alexander L. Gerbes, Anton Laggner, Arendt, Barratt-Boyes, Barry, Bauch, Brenner, Bruno Schneeweiss, Burnett, Cohn, Davies, Epstein, Epstein, Epstein, Fernandez-Seara, Fischer, Fried, Fyrquist, Ganger, Ganong, Georg Grimm, Gerbes, Gerbes, Gerbes, Gerbes, Gornel, Granger, Haber, Harald Reither, Heide Hörtnagl, Heinrich, Heyndrickx, Hintze, Holtz, Hörtnagl, Katsube, Kew, Klepetko, Koepke, Kontos, Kotelanski, Kurt Lenz, Lancestremere, Lenz, Lenz, Lenz, López, Manning, Marin-Grez, Murray, Needleman, Nicholls, Oshima, Panos, Petrillo, Rainer Schmid, Richards, Salerno, Salerno, Schenker, Schmid, Schrier, Shapiro, Siegel, Solis-Herruzo, Wernze, Wilfred Druml   +66 more
core   +1 more source

Regulation of Renin Release via Cyclic ADP-Ribose-Mediated Signaling: Evidence from Mice Lacking CD38 Gene

Cellular Physiology and Biochemistry, 2013
Background/Aims: Despite extensive studies, the intracellular regulatory mechanism of renin production and release is still poorly understood. The present study was designed to test whether CD38-ADP-ribosylcyclase signaling pathway contributes to the ...
Jing Xiong, Min Xia, Fan Yi, Justine M. Abais, Ningjun Li, Krishna M. Boini, Pin-Lan Li   +6 more
doaj   +1 more source

Reduced blood pressure in sickle cell disease is associated with decreased angiotensin converting enzyme (ACE) activity and is not modulated by ACE inhibition.

PLoS ONE, 2022
BackgroundSickle cell disease (SCD) incurs vaso-occlusive episodes and organ damage, including nephropathy. Despite displaying characteristics of vascular dysfunction, SCD patients tend to present relatively lower systemic blood pressure (BP), via an ...
Pamela L Brito, Alisson F Dos Santos, Hanan Chweih, Maria E Favero, Erica M F Gotardo, Juliete A F Silva, Flavia C Leonardo, Carla F Franco-Penteado, Mariana G de Oliveira, Wilson A Ferreira, Bruna C Zaidan, Athanase Billis, Giorgio Baldanzi, Denise A Mashima, Edson Antunes, Sara T Olalla Saad, Fernando F Costa, Nicola Conran   +17 more
doaj   +1 more source

Advantages of the new loop diuretic torasemide over furosemide in patients with cirrhosis and ascites [PDF]

, 1993
Torasemide is a new loop diuretic with a longer half-life and longer action than furosemide in healthy subjects. In order to evaluate the pharmacodynamic effects, single oral doses of furosemide (80 mg) and torasemide (20 mg), which were equipotent in ...
Bertheau-Reitha, Ute, Falkner, Christine, Gerbes, Alexander L., Jüngst, Dieter, Paumgartner, Gustav   +4 more
core   +1 more source

Performance of renin assays in selecting fludrocortisone dose in children with adrenal disorders

Endocrine Connections
Children with salt-wasting adrenal insufficiency are managed with glucocorticoid and mineralocorticoid replacement. Measurement of renin activity or concentration alongside blood electrolyte levels is used to monitor the adequacy of mineralocorticoid ...
Timothy J Morris, Andrew Whatmore, Laura Hamilton, Beverly Hird, Eric S Kilpatrick, Lesley Tetlow, Peter Clayton   +6 more
doaj   +1 more source

Effect of Breed on Plasma Endothelin‐1 Concentration, Plasma Renin Activity, and Serum Cortisol Concentration in Healthy Dogs

Journal of Veterinary Internal Medicine, 2016
Background There are breed differences in several blood variables in healthy dogs. Objective Investigate breed variation in plasma endothelin‐1 (ET‐1) concentration, plasma renin activity, and serum cortisol concentration. Animals Five‐hundred and thirty‐
K. Höglund, A.‐S. Lequarré, I. Ljungvall, K. Mc Entee, A.‐C. Merveille, M. Wiberg, V. Gouni, J. Lundgren Willesen, S. Hanås, G. Wess, L. Mejer Sørensen, L. Tiret, M. Kierczak, S.K.G. Forsberg, E. Seppälä, K. Lindblad‐Toh, H. Lohi, V. Chetboul, M. Fredholm, J. Häggström   +19 more
doaj   +1 more source

Hypoglycemia Induces Diabetic Macrovascular Endothelial Dysfunction via Endothelial Cell PANoptosis, Macrophage Polarization, and VSMC Fibrosis

Advanced Science, EarlyView.
This study investigates hypoglycemia‐induced diabetic macrovascular endothelial dysfunction. It reveals that hypoglycemia triggers ZBP1‐dependent PANoptosis of endothelial cells, proinflammatory polarization of macrophages, and fibrosis of vascular smooth muscle cells (VSMCs) in diabetic mice.
Deyu Zuo, Yuce Peng, Guozhi Zhao, Zhesheng Cheng, Minghao Luo, Dingyi Lv, Shuting Chang, Na Li, Yanyao Huang, Xunjia Li, An He   +10 more
wiley   +1 more source