Results 21 to 30 of about 1,320,101 (268)

Extracellular tumor-related mRNA in plasma of lymphoma patients and survival implications. [PDF]

PLoS ONE, 2009
BACKGROUND: We studied anomalous extracellular mRNAs in plasma from patients with diffuse large B-cell lymphoma (DLBCL) and their survival implications.
Vanesa Garcia, Jose Miguel Garcia, Javier Silva, Paloma Martin, Cristina Peña, Gemma Dominguez, Raquel Diaz, Mercedes Herrera, Constanza Maximiano, Pilar Sabin, Antonio Rueda, Miguel Angel Cruz, Jose Rodriguez, Miguel Angel Canales, Felix Bonilla, Mariano Provencio   +15 more
doaj   +1 more source

The dielectric response function for an anisotropic plasma [PDF]

Physics Letters A, 1972
Abstract We demonstrate how approximations may be obtained for the longitudinal dielectric response function of the anisotropic plasma of Joyce and Montgomery by the simple additivity principle for the susceptibility and by a Galilean transformation of the Lindhard expression.
Dekeyser, Raf, Saxena, Vk, Imamuddin, M.
openaire   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Relationship between labile plasma iron, liver iron concentration and cardiac response in a deferasirox monotherapy trial

Haematologica, 2011
The US04 trial was a multicenter, open-label, single arm trial of deferasirox monotherapy (30–40 mg/kg/day) for 18 months. Cardiac iron response was bimodal with improvements observed in patients with mild to moderate initial somatic iron stores ...
John C. Wood, Tara Glynos, Alexis Thompson, Patricia Giardina, Paul Harmatz, Barinder P. Kang, Carole Paley, Thomas D. Coates   +7 more
doaj   +1 more source

Thioridazine plasma levels and clinical response

Comprehensive Psychiatry, 1975
Summary o 1. The relationship between indices of plasma thioridazine concentration (half-life, area under curve, peak level) and clinical response was examined over a 10-day period in 25 patients with severe to moderately severe acute schizophrenia following a single oral dose (on day one) of a placebo and of thioridazine, 4 mg/kg (on day 6).
L A, Gottschalk, R, Biener, E P, Noble, H, Birch, D E, Wilbert, J F, Heiser   +5 more
openaire   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Deep learning based plasma response models to 3D external magnetic field perturbations in EAST

Nuclear Fusion
The real-time response monitoring model and the physics feature based response optimization model are proposed on EAST using three deep learning models.
Jian Xu, Shuai Gu, Huihui Wang, Youwen Sun, Zhengxiong Wang, Guohong Deng, Tonghui Shi, Jinze Shi, Hua Yang, Cheng Ye, Qun Ma, Hui Sheng, Wenyi Lu, Yaoning Zhang, Gaoting Chen, Dalong Chen, Biao Shen, Jinping Qian, Zhengping Luo   +18 more
doaj   +1 more source

PLASMA CATECHOLAMINE RESPONSES TO TRACHEAL INTUBATION

British Journal of Anaesthesia, 1983
Plasma adrenaline and noradrenaline concentrations were measured in 24 patients during the induction of anaesthesia and the subsequent tracheal intubation. The patients received either suxamethonium 1 mg kg-1 or pancuronium 0.1 mg kg-1 to facilitate tracheal intubation.
D R, Derbyshire, A, Chmielewski, D, Fell, M, Vater, K, Achola, G, Smith   +5 more
openaire   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source