Results 31 to 40 of about 1,320,101 (268)

Optimizing RMP spectrum for the minimization of fast-ion losses during ELM control

Nuclear Fusion
Minimization of fast-ion losses induced by the 3D effects has been a topic of key importance in the context of controlling edge localized modes (ELMs) using resonant magnetic perturbations (RMPs).
Yao-Ning Zhang, Kai-Yang He, You-Wen Sun, Bao-Nian Wan, Xue-Min Wu, Peng-Cheng Xie, Yue-Qiang Liu   +6 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Comparison of plasma response models for RMP effects on the divertor and scrape-off layer in KSTAR

Nuclear Fusion
Resonant magnetic perturbations (RMPs) are beneficial for control of edge localized modes (ELMs) in tokamaks. Nevertheless, a side effect of RMPs is the appearance of helical striations in the particle and heat loads onto divertor targets. The extent and
H. Frerichs, J. Van Blarcum, T. Cote, S.K. Kim, Y.Q. Liu, S.M. Yang   +5 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Impact of error fields and error field correction on heat fluxes in SPARC

Nuclear Fusion
Using a single toroidal array of coils to reduce the $m,n = 2,1$ resonant error field (EF) produced by the misalignment of the axisymmetric coils in SPARC can result in the enhancement of the local divertor heat fluxes. Managing high divertor heat fluxes
S. Munaretto, A. Kleiner, R.M. Churchill, D. Corona, T. Looby, M. Scotto d’Abusco, A. Wingen   +6 more
doaj   +1 more source

Influence of kinetic effects on plasma response to resonant magnetic perturbations in HL-2A tokamak

He jishu
BackgroundThe control of edge localized modes (ELMs) is a key issue for the safety operation of ITER and future magnetic confinement fusion reactors.
LIU Yihuizi, ZHANG Neng, LIU Yueqiang, GONG Xueyu, WANG Shuo, LI Chunyu, WANG Lian, HAO Guangzhou   +7 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

A new type of resonant magnetic perturbation for controlling edge localized modes

Nuclear Fusion
A new type of resonant magnetic perturbation (RMP), generated by helical coils, is proposed for controlling the edge localized mode (ELM) in H-mode tokamak plasmas. The helical coil optimization utilizes the MARS-F code (Liu et al 2000 Phys.
Xu Yang, Yueqiang Liu, Xuan Sun, Wei Xu, Li Li, Yuling He, Guoliang Xia, Hanqing Hu, Lina Zhou   +8 more
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source