Results 41 to 50 of about 2,312,825 (297)

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi, Daisuke Katagiri, Takeyuki Watadani, Shunichi Matsuda, Hiroshi Kaneko, Noritoshi Arai   +5 more
wiley   +1 more source

Impact of error fields and error field correction on heat fluxes in SPARC

Nuclear Fusion
Using a single toroidal array of coils to reduce the $m,n = 2,1$ resonant error field (EF) produced by the misalignment of the axisymmetric coils in SPARC can result in the enhancement of the local divertor heat fluxes. Managing high divertor heat fluxes
S. Munaretto, A. Kleiner, R.M. Churchill, D. Corona, T. Looby, M. Scotto d’Abusco, A. Wingen   +6 more
doaj   +1 more source

Influence of kinetic effects on plasma response to resonant magnetic perturbations in HL-2A tokamak

He jishu
BackgroundThe control of edge localized modes (ELMs) is a key issue for the safety operation of ITER and future magnetic confinement fusion reactors.
LIU Yihuizi, ZHANG Neng, LIU Yueqiang, GONG Xueyu, WANG Shuo, LI Chunyu, WANG Lian, HAO Guangzhou   +7 more
doaj   +1 more source

Probing Color Response - Wakes in a Color Plasma

, 2005
The wake induced in a hot QCD medium by a high momentum parton (jet precursor) is calculated in the framework of linear response theory. Two different scenarios are discussed: a weakly coupled quark gluon plasma (pQGP) as described by hard-thermal loop ...
Accardi A, Casalderrey-Solana J, Glassgold A E, Ichimaru S, Jörg Ruppert, Klimov V V, Kovner A, LeBellac M, Satarov L M, Schäfer W, Shuryak E V, Stöcker H, Wang F   +12 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

A new type of resonant magnetic perturbation for controlling edge localized modes

Nuclear Fusion
A new type of resonant magnetic perturbation (RMP), generated by helical coils, is proposed for controlling the edge localized mode (ELM) in H-mode tokamak plasmas. The helical coil optimization utilizes the MARS-F code (Liu et al 2000 Phys.
Xu Yang, Yueqiang Liu, Xuan Sun, Wei Xu, Li Li, Yuling He, Guoliang Xia, Hanqing Hu, Lina Zhou   +8 more
doaj   +1 more source

Introduction of Macromolecules into Bovine Adrenal Medullary Chromaffin Cells and Rat Pheochromocytoma Cells (PC12) by Permeabilization with Streptolysin O: Inhibitory Effect of Tetanus Toxin on Catecholamine Secretion [PDF]

, 1989
Conditions are described for controlled plasma membrane permeabilization of rat pheochromocytoma cells (PC12) and cultured bovine adrenal chromaffin cells by Streptolysin O (SLO).
Ahnert-Hilger G., Ahnert-Hilger G., Ahnert-Hilger G., Bader M. F., Bhakdi S., Bhakdi S., Bhakdi S., Bittner M. A., Brooks J. C., Cazalis M., Duncan J. L., Flodgaard H., Gudrun Ahnert-Hilger, Habermann E., Hugo F., Jahn R., Knight D. E, Manfred Gratzl, Marie-France Bader, Peppers S. C., Rehm H., Sarafian T., Sillen L. G., Simon W., Smyth C. I., Sontag J. M., Sternberger A., Sucharit Bhakdi, Walton K. M., Wilson S. P.   +29 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Plasma catecholamines during activation of the sympathetic nervous system in a patient with Shy-Drager syndrome. [PDF]

, 1980
Plasma catecholamines and circulation parameters were studied in a patient with a Shy-Drager syndrome. Basal values of free noradrenaline and dopamine were within the normal range, whereas the adrenaline level was decreased.
Gross, G., Krause, Klaus-Henning, Nagel-Hiemke, M.   +2 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source