Results 61 to 70 of about 1,320,101 (268)

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Influence of the far non-resonant components of high-n resonant magnetic perturbations on energetic passing ions loss

Nuclear Fusion
The influence on the loss of energetic passing ions by the n  = 4 resonant magnetic perturbation (RMP) is investigated through numerical simulations (here, n is the toroidal mode number of the RMP field).
Yao-Ning Zhang, Kai-Yang He, You-Wen Sun, Bao-Nian Wan, Xue-Min Wu, Peng-Cheng Xie, Yue-Qiang Liu   +6 more
doaj   +1 more source

miRNA signature associated with R–CHOP refractoriness in patients diagnosed with diffuse large B cell lymphoma

Non-coding RNA Research, 2020
Refractoriness remains as one of the challenges in patients with lymphoma under chemotherapy, and among biological regulators in cells driving this type of response are microRNAs (miRNAs).
Oscar Raul Fajardo-Ramirez, Luis Villela, Jocelyn Nikita Campa-Carranza, Antonio Ali Perez-Maya, Gissela Borrego-Soto, Martin Ivan Wah-Suarez, Iram Pablo Rodríguez-Sánchez, Patricio A. Zapata-Morin, Rocio Ortiz-Lopez, Victor Manuel Treviño, Mariano Garcia-Magariño, Ivan Alberto Marino-Martinez   +11 more
doaj   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Plasma Oxidized W-WOx Sensor for Sub-ppm H2S Detection

Proceedings, 2017
In this work we have fabricated W-WOx core-shell nanowire structure using plasma oxidation, a CMOS compatible process, for sensing H2S gas. For comparison, the sputtered stack structure of W-WOx with different thickness ratios of W to WOx is fabricated ...
Samatha Benedict, Navakanta Bhat
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Association of plasma ferritin and plasma iron at time of vaccination with the immune response to SARS-CoV-2 vaccination: a longitudinal cohort study

Frontiers in Immunology
IntroductionRecent studies have shown a link between iron status and immune response following infection or vaccination. We aimed to investigate whether plasma ferritin and plasma iron concentrations at time of vaccination were associated with the ...
Giulia Pestoni, Dominik Menges, Craig Fenwick, Pornpimol Scheuchzer, Julia Braun, Sarah R. Haile, Tala Ballouz, Christophe Zeder, Christophe Zeder, Nicole U. Stoffel, Nicole U. Stoffel, Michael B. Zimmermann, Milo A. Puhan, Anja Frei, Diego Moretti   +14 more
doaj   +1 more source

Effect of Type of Pregnancy on Transcriptional and Plasma Metabolic Response in Sheep and Its Further Effect on Progeny Lambs

Animals, 2020
The following study was performed in order to determine the effect of type of pregnancy on the transcriptional expression of genes that are engaged in angiogenesis and cell turnover/lactogenesis in the ewe mammary gland, evaluating its impact on the ...
María Gallardo Paffetti, Juan Cárcamo, Luis Arias-Darraz, Carlos Alvear, Javier Ojeda   +4 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Non-hydrodynamic response in QCD-like plasma

Journal of High Energy Physics
Quark-gluon plasma’s (QGP) properties at non-hydrodynamic and non-perturbative regimes remain largely unexplored. Here, we examine the response functions describing how a QGP-like plasma responds to initial energy-momentum disturbance in both static and ...
Weiyao Ke, Yi Yin
doaj   +1 more source