Results 81 to 90 of about 31,621 (232)

Cardiovascular toxicity from immune checkpoint inhibitor therapy: an inflammatory continuum

British Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitor (ICI) therapy has markedly improved outcomes in advanced malignancies but has also revealed a distinct spectrum of cardiovascular immune‐related adverse events. Myocarditis represents the most severe manifestation, while non‐inflammatory left ventricular dysfunction and vascular inflammation have emerged as additional ...
Fabrice Reyes, Florian Buehning, Tobias Lerchner, Julia Vogel, Raluca I. Mincu, Matthias Totzeck, Tienush Rassaf, Lars Michel   +7 more
wiley   +1 more source

Refining the treatment of immune checkpoint inhibitor–associated myocarditis: Challenges, innovations and rechallenge considerations

British Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitor (ICI)‐associated myocarditis has emerged as a severe and clinically complex immune‐related toxicity that poses significant challenges for therapeutic decision‐making in routine cardio‐oncological care. High‐dose corticosteroids remain the first‐line therapy, yet their timing, dosage and tapering require careful clinical ...
Raluca I. Mincu, Lisa Zimmer, Dimitra Vlachopoulou, Elias Haj‐Yehia, Julia Hoffmann, Lars Michel, Elisabeth Livingstone, Dirk Schadendorf, Alpaslan Tasdogan, Matthias Totzeck, Tienush Rassaf   +10 more
wiley   +1 more source

Plasmapheresis for refractory toxic epidermal necrolysis unresponsive to conventional therapy: a case report and literature review

Frontiers in Immunology
Toxic epidermal necrolysis (TEN) is a rare and life-threatening severe cutaneous adverse reaction. The conventional treatment approach includes immunomodulatory therapies, such as systemic corticosteroids, cyclosporine, intravenous immunoglobulin (IVIG),
Shun-Qi Liao, Zhang-Rong Yan, Lun-Wei Lin, Ming Deng, Guo-Jin Xiao, Pei-Yang Gao   +5 more
doaj   +1 more source

Successful desensitization and kidney transplantation in the presence of donor-specific anti-human leukocyte antigen antibodies in kidney transplant recipients

Saudi Journal of Kidney Diseases and Transplantation, 2020
Kidney transplantation has indisputably revamped renal medicine and restored hope among patients coming across fatal end-stage renal disease. However, sensitization of human leukocyte antigen (HLA) triggers extensive immunological fences to successful ...
Muhammad Tassaduq Khan, Rashid bin Hamid, Sabahat Sarfaraz, Naranjan Lal, Jaleel Ahmed, Shobha Luxmi   +5 more
doaj   +1 more source

Role of plasmapheresis in immunological kidney diseases. Experience from 1050 completed plasmapheresis treatment sessions

, 2011
Plasmapheresis is an effective treatment modality in several immunological kidney diseases. It is also indicated in certain neurological and hematological abnormalities, and some other diseases.
Henrik Braunitzer, Ágnes Haris, József Arányi, Zoltán Merán, Mariann Soltész, Kálmán Polner, Éva Kálmán   +6 more
core   +1 more source

Early tocilizumab and outcomes in acute necrotizing encephalopathy

Developmental Medicine &Child Neurology, EarlyView.
Early tocilizumab and outcome in acute necrotising encephalopathy. Aim To evaluate the timing and safety of tocilizumab in acute necrotizing encephalopathy (ANE). Method This was a multicentre retrospective study evaluating outcomes (modified Rankin Scale [mRS]) in children with ANE treated with tocilizumab. A logistic regression model determined a cut‐
Velda X Han, Prithuja Poudyal, Vanessa Lee, Arushi Gahlot Saini, Shekeeb S Mohammad, Sekhar C Pillai, Gouri Rao Passi, Naveen Sankhyan, Ahmad Rithauddin Mohamed, Lokesh Lingappa, Hiroshi Sakuma, Russell C Dale, Ming Lim, Terrence Thomas, for The International ANE Study Group   +14 more
wiley   +1 more source

Applications of plasmapheresis in therapy and in blood components preparation [PDF]

, 2012
Plasmapheresis is a medical procedure consists of removal of the blood, separation of cells from plasma, and return of these cells to the body’s circulation by reinfusion. There are therapeutic and preparative plasmapheresis.
Kondera-Anasz, Zdzisława, Gęsikowska, Karina, Mielczarek-Palacz, Aleksandra, Machaj, Iwona, Sikora, Justyna, Smycz, Marta   +5 more
core  

The role of therapeutic plasmapheresis in patients with hyperthyroidism

, 2020
Background: Hyperthyroidism is characterized by excess hormone secretion from the thyroid gland. Anti-thyroid drugs (ATDs), surgery, and radioactive iodine can be used in treatment.
Koseoglu, Derya, Baser, ÖZDEN, Cetin, Zeynep, Catak, Merve, Berker, Dilek, Baser, Ozden Ozdemir   +5 more
core   +1 more source

Platelet concentrates in sinus augmentation: The impact of platelet dose and biological characteristics—A systematic review and meta‐analysis

European Journal of Oral Sciences, EarlyView.
Abstract This systematic review investigated the osteogenic effects of platelet concentrate (PRF/PRP) when combined with non‐autogenous graft materials in sinus lift procedures. Key characteristics assessed included platelet concentration, total platelet dose, leukocyte content, and fibrin‐network structure.
Olav Kansgar Straum, Hans Thomas Brox, Juliane Hesse, Andreas Jörn Schmalfuss, Erlend Bugge   +4 more
wiley   +1 more source

Atrophic Papulosis: A Systematic Review of Pediatric Cases

Pediatric Dermatology, EarlyView.
ABSTRACT Background Atrophic papulosis is a rare occlusive vasculopathy that can present with isolated cutaneous disease or with systemic involvement. Pediatric cases are uncommon, and existing reports are heterogeneous, limiting understanding of disease patterns, timing of organ involvement, and outcomes.
Ou Jia Emilie Wang, Alennie Lopez, Renee Gabrielle Fajardo, Richard I. Crawford, Joseph M. Lam   +4 more
wiley   +1 more source