Results 131 to 140 of about 1,390,499 (412)
Plasmid interference for curing antibiotic resistance plasmids in vivo [PDF]
PLOS ONE, 2017 Antibiotic resistance increases the likelihood of death from infection by common pathogens such as Escherichia coli and Klebsiella pneumoniae in developed and developing countries alike. Most important modern antibiotic resistance genes spread between such species on self-transmissible (conjugative) plasmids. These plasmids are traditionally grouped on
M. Kamruzzaman +6 more
openaire +4 more sources
Journal of Bacteriology, 1983 The production and regeneration of bacterial protoplasts promoted the loss of three different plasmid-specified traits in Streptococcus lactis subsp. diacetylactis strains.
M. Gasson
semanticscholar +1 more source
Molecular Oncology, EarlyView.CircCCNB1 expression is down‐regulated in nasopharyngeal carcinoma (NPC); thus, less NF90 protein is bound to circCCNB1 and more binds to pri‐miRNAs, blocking their (pri‐miRNAs) binding to DGCR8 and inhibiting the processing and generation of miR‐15b‐5p/miR‐7‐1‐3p. Furthermore, decreased miR‐15b‐5p/miR‐7‐1‐3p promotes the expression of the target genes
Chunmei Fan +6 more
wiley +1 more source
Plasmid- mediated cefotaxime and ceftizoximd resistance in Ten strains of klebsiella pneumoniae isolated from hospitals in Kerman,Iran [PDF]
Journal of Kerman University of Medical Sciences, 1997 Klebsiella pneumonia is a gram negative bacillus of which it's resistant strains are a common source of nosocomial infections . The goal of this study is determination of drug sensitivity of these resistant strains, and study of causes involved in the ...
M.R Shakibaei, A.H GHolamali big
doaj
Resistance Plasmid Families in Enterobacteriaceae
Antimicrobial Agents and Chemotherapy, 2009 Bacteria carry extrachromosomal, self-replicating genetic elements called plasmids. A plasmid is defined as a double-stranded, circular DNA molecule capable of autonomous replication. By definition, plasmids do not carry genes essential for the growth of
A. Carattoli
semanticscholar +1 more source
Molecular Oncology, EarlyView.TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam +9 more
wiley +1 more source
Insights into a Novel blaKPC-2-Encoding IncP-6 Plasmid Reveal Carbapenem-Resistance Circulation in Several Enterobacteriaceae Species from Wastewater and a Hospital Source in Spain [PDF]
, 2017 Untreated wastewater, particularly from hospitals and other healthcare facilities, is considered to be a reservoir for multidrug-resistant bacteria.
Cantón, Rafael +8 more
core +1 more source
Stochastic Simulations of the Repressilator Circuit [PDF]
, 2007 The genetic repressilator circuit consists of three transcription factors, or repressors, which negatively regulate each other in a cyclic manner. This circuit was synthetically constructed on plasmids in {\it Escherichia coli} and was found to exhibit oscillations in the concentrations of the three repressors.
arxiv +1 more source
Selection of a Multidrug Resistance Plasmid by Sublethal Levels of Antibiotics and Heavy Metals
mBio, 2014 How sublethal levels of antibiotics and heavy metals select for clinically important multidrug resistance plasmids is largely unknown. Carriage of plasmids generally confers substantial fitness costs, implying that for the plasmid-carrying bacteria to be
E. Gullberg +4 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini +10 more
wiley +1 more source