Results 211 to 220 of about 982,599 (302)

Extracellular vesicle mimetics as delivery vehicles for oligonucleotide-based therapeutics and plasmid DNA. [PDF]

Front Bioeng Biotechnol
Oshchepkova A, Chernikov I, Miroshnichenko S, Patutina O, Markov O, Savin I, Staroseletz Y, Meschaninova M, Puchkov P, Zhukov S, Kupryushkin M, Maslov M, Sen'kova A, Vlassov V, Chernolovskaya E, Zenkova M.   +15 more
europepmc   +1 more source

Mutation of Surface Histidines in \u3ci\u3eHaemophilus influenzae\u3c/i\u3e Carbonic Anhydrase to Enable Purification by Metal Affinity Chromatography [PDF]

, 2016
Cornely, Kathleen, Scola, Shelby E.
core   +1 more source

MicroRNA‐375‐3p Targets Fatty Acid Synthase and Relish to Regulate Energy Allocation During Pupal Metamorphosis and Starvation

Advanced Science, EarlyView.
During pupal metamorphosis and starvation, elevated 20‐hydroxyecdysone (20E) and suppressed insulin trigger Forkhead box O (FOXO) nuclear translocation, enhancing miR‐375‐3p expression. This downregulates fatty acid synthase (FASN) and Relish, promoting lipid breakdown for energy while prioritizing antioxidant responses over immune functions to support
Peng Chen, Meiqi Cheng, Jianhui Wang, Jing Tang, Xiaoqiao Huang, Yusi Li, Huiling Zhou, Ling Zhang, Yi Dong, Chengjun Li, Bin Li   +10 more
wiley   +1 more source

From plasmid sequence to process design: A computational analysis of metabolism in the context of plasmid DNA manufacturing

Stratis N, Morbidelli M, Kiparissides A.
europepmc   +1 more source

Rapid quantitative analysis of double-stranded plasmid DNA with capillary gel electrophoresis for applications in quality control and radiation research. [PDF]

Sci Rep
Hahn MB.
europepmc   +1 more source

ITGB1 Regulates Triple‐Negative Breast Cancer Development by Modulating the Tumor Microenvironment

Advanced Science, EarlyView.
ABSTRACT Tumorigenesis and metastasis are frequently attributed to the intricate interplay between cancer cells and the tumor microenvironment (TME). Comprehending the mechanisms and key regulators of cancer‐immune crosstalk in the TME is imperative for developing efficacious immunotherapy.
Nuozi Song, Siqi Chen, Lei Wang, Jessica Dang, Xu Cao, Stephanie Singh, Lu Yang, Jinhui Wang, Steven T. Rosen, Yingyu Wang, Chun‐Wei D. Chen, Cheng Zhang, Mingye Feng   +12 more
wiley   +1 more source

Retraction for Ruby and Novick, Plasmid interactions in <i>Staphylococcus aureus</i>: Nonadditivity of compatible plasmid DNA pools. [PDF]

Proc Natl Acad Sci U S A
europepmc   +1 more source

Pathologic Tissue Injury and Inflammation in Mice Immunized with Plasmid DNA-Encapsulated DOTAP-Based Lipid Nanoparticles. [PDF]

Bioconjug Chem
Peng S, Zhang Y, Zhao X, Wang Y, Zhang Z, Zhang X, Li J, Zheng H, Zhang Y, Shi H, Li H, Liu L.   +11 more
europepmc   +1 more source

Endocytic Control of Cell‐Autonomous and Non‐Cell‐Autonomous Functions of p53

Advanced Science, EarlyView.
NUMB Ex3‐containing isoforms localize to the plasma membrane, where they recruit p53 through SNX9 and direct it to multivesicular bodies and exosomes. Exported p53 is taken up by neighboring cells and activates nuclear programs, revealing an intercellular, exosome‐based pathway that might help establish a tumor‐suppressive microenvironment.
Roberta Cacciatore, Andrea Basile, Stefano Freddi, Irene Schiano Lomoriello, Carlo Ribelle Zucca, Giuseppe Ciossani, Luigi Scietti, Alessandro Cuomo, Simona Ronzoni, Simone Pelicci, Mario Faretta, Elena Zaccheroni, Giuliana Pelicci, Vittoria Matafora, Angela Bachi, Rosalind Helen Gunby, Salvatore Pece, Sara Sigismund, Letizia Lanzetti, Ivan Nicola Colaluca, Pier Paolo Di Fiore   +20 more
wiley   +1 more source

Exosome-membrane and polymer-based hybrid-complex for systemic delivery of plasmid DNA into brains for the treatment of glioblastoma. [PDF]

Asian J Pharm Sci
Lee Y, Kang S, Thuy LT, Son M, Park JY, Ahn SB, Kang M, Oh J, Choi JS, Lee M.   +9 more
europepmc   +1 more source