Results 271 to 280 of about 741,058 (313)
Some of the next articles are maybe not open access.

Plasmid-partition functions of the P7 prophage

Journal of Molecular Biology, 1989
The sequences responsible for the proper partition of the P7 plasmid prophage to daughter cells lie within a discrete block of non-similarity between P7 and its close relative P1. The DNA sequence of the P7 region was determined. A segment with near identity to the replication (rep) region of P1 is followed by sequences (P7 par) that are clearly ...
D N, Ludtke, B G, Eichorn, S J, Austin
openaire   +2 more sources

Plasmid partitioning superstructure system

Science, 2015
DNA Segregation Partitioning and sharing DNA between dividing cells is critical for all domains of life. Prokaryotes must share certain plasmids as well as their genomic DNA to survive. Schumacher et al. studied the partition system that segregates a conjugative plasmid in the prokaryote Sulfolobus. The system consists of three proteins.
openaire   +1 more source

Partition of Plasmid R1: A Computer Simulation

Plasmid, 1993
A computer-simulated population of individual Escherichia coli cells harboring plasmid R1 parA+/parB- has been used to analyze three possible modes of plasmid segregation: equi-partition, in which plasmids are partitioned equally to daughter cells at cell division; single-site inheritance, in which the products of the most recent replication event are ...
R, Rosenfeld, N B, Grover
openaire   +2 more sources

Altered ParA partition proteins of plasmid P1 act via the partition site to block plasmid propagation

Molecular Microbiology, 1997
The partition system of the P1 plasmid, P1parconsists of the ParA and ParB proteins and a cis‐acting site, parS. It is responsible for the orderly segregation of plasmid copies to daughter cells. Plasmids with null mutations in parA or parB replicate normally, but missegregate.
B, Youngren, S, Austin
openaire   +2 more sources

Partition Systems of Bacterial Plasmids

2014
Plasmids, as extrachromosomal elements, bear the burden of ensuring their own faithful segregation at cell division. This chapter reviews partition systems, which are, in general, systems that actively dictate the specific localization of plasmids inside the bacterial cell and coordinate this localization with the bacterial cell cycle.
Barbara E. Funnell, Roderick A. Slavcev
openaire   +1 more source

Segregation of the yeast plasmid: similarities and contrasts with bacterial plasmid partitioning

Plasmid, 2004
The high copy yeast plasmid 2 microm circle, like the well-studied low copy bacterial plasmids, utilizes two partitioning proteins and a cis-acting 'centromere'-like sequence for its stable propagation. Functionally, though, the protein and DNA constituents of the two partitioning systems are quite distinct.
Makkuni, Jayaram   +3 more
openaire   +2 more sources

Clustering versus random segregation of plasmids lacking a partitioning function: a plasmid paradox?

Plasmid, 2003
Plasmids lacking a functional partition system are randomly distributed to the daughter cells; plasmid-free daughter cells are formed with a frequency of (1/2)2n per cell and cell generation where 2n is the (average) copy number at cell division. Hence, the unit of segregation is one plasmid copy. However, plasmids form clusters in the cells.
Nordström, K., Gerdes, K.
openaire   +4 more sources

Partition mechanism of F plasmid: Two plasmid gene-encoded products and a cis-acting region are involved in partition

Cell, 1983
Plasmids that replicate using the replication origin (oriC) of the E. coli chromosome are not stably inherited through cell division, but can be stabilized by joining with a particular segment of F plasmid that presumably provides the partition function.
T, Ogura, S, Hiraga
openaire   +2 more sources

Partitioning of the pSC101 Plasmid during Cell Division

1985
It is generally accepted that a mechanism must exist for ensuring that each of the products of a bacterial cell division receives a copy of the chromosome. However, until recently, the existence of a specific mechanism for actively distributing extrachromosomal elements such as plasmids to daughter cells was less clear.
S N, Cohen   +4 more
openaire   +2 more sources

The Molecular Genetics of Plasmid Partition: Special Vector Systems for the Analysis of Plasmid Partition

1989
Plasmids are autonomously replicating elements that are dispensable for cell viability and are therefore vulnerable to loss from the growing cells. However, naturally occurring plasmids are very stably maintained in populations of the host bacteria. Thus, the individual copies must be distributed within the dividing cell in such a way as to ensure that
Ann L. Abeles, Stuart J. Austin
openaire   +1 more source

Home - About - Disclaimer - Privacy