Results 31 to 40 of about 299,331 (269)
ParAB Partition Dynamics in Firmicutes: Nucleoid Bound ParA Captures and Tethers ParB-Plasmid Complexes. [PDF]
PLoS ONE, 2015 In Firmicutes, small homodimeric ParA-like (δ2) and ParB-like (ω2) proteins, in concert with cis-acting plasmid-borne parS and the host chromosome, secure stable plasmid inheritance in a growing bacterial population.
Virginia S Lioy +5 more
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Life, 2021 Gene therapy and DNA vaccination are among the most expected biotechnological and medical advances for the coming years. However, the lack of cost-effective large-scale production and purification of pharmaceutical-grade plasmid DNA (pDNA) still hampers ...
Nuno R. da Silva +4 more
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pTAR-Encoded Proteins in Plasmid Partitioning [PDF]
Journal of Bacteriology, 2000 ABSTRACT Partition cassettes, essential for the segregational stability of low-copy-number bacterial plasmids, typically encode two autoregulated proteins and an adjacent cis -acting centromere analog to which one or perhaps both proteins bind.
K, Kalnin, S, Stegalkina, M, Yarmolinsky
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A conserved mechanism drives partition complex assembly on bacterial chromosomes and plasmids
Molecular Systems Biology, 2018 Chromosome and plasmid segregation in bacteria are mostly driven by ParABS systems. These DNA partitioning machineries rely on large nucleoprotein complexes assembled on centromere sites (parS).
Roxanne E Debaugny +11 more
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PLoS ONE, 2012 This study characterizes the 21.4 kilobase plasmid pECTm80 isolated from Escherichia coli strain 80, an α hemolytic human clinical diarrhoeal isolate (serotype O108:H-).
Fay E Dawes +6 more
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Open Research Europe, 2023 Antimicrobial resistance is a persistent challenge in human and veterinary medicine, which is often encoded on plasmids which are transmissible between bacterial cells.
Jaap Wagenaar +5 more
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Klebsiella pneumoniae multiresistance plasmid pMET1: similarity with the Yersinia pestis plasmid pCRY and integrative conjugative elements. [PDF]
PLoS ONE, 2008 Dissemination of antimicrobial resistance genes has become an important public health and biodefense threat. Plasmids are important contributors to the rapid acquisition of antibiotic resistance by pathogenic bacteria.The nucleotide sequence of the ...
Alfonso J C Soler Bistué +12 more
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Multiple and Diverse vsp and vlp Sequences in Borrelia miyamotoi, a Hard Tick-Borne Zoonotic Pathogen. [PDF]
PLoS ONE, 2016 Based on chromosome sequences, the human pathogen Borrelia miyamotoi phylogenetically clusters with species that cause relapsing fever. But atypically for relapsing fever agents, B. miyamotoi is transmitted not by soft ticks but by hard ticks, which also
Alan G Barbour
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Sequence of two plasmids from Clostridium perfringens chicken necrotic enteritis isolates and comparison with C. perfringens conjugative plasmids. [PDF]
PLoS ONE, 2012 Twenty-six isolates of Clostridium perfringens of different MLST types from chickens with necrotic enteritis (NE) (15 netB-positive) or from healthy chickens (6 netB-positive, 5 netB-negative) were found to contain 1-4 large plasmids, with most netB ...
Valeria R Parreira +4 more
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Partition site of the P1 plasmid. [PDF]
Proceedings of the National Academy of Sciences, 1987 We have defined a minimal partition site, parS, from the plasmid P1. It contains sufficient cis-acting information to direct accurate segregation of low-copy-number plasmids that contain it as long as the two essential P1 Par proteins are supplied in trans. The site is, at most, 34 base pairs and contains a perfect 13-base-pair inverted repeat.
K A, Martin, S A, Friedman, S J, Austin
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