Results 11 to 20 of about 299,331 (269)

Plasmid segregation without partition [PDF]

open access: yesMobile Genetic Elements, 2012
Low-copy number plasmids need a segregation mechanism to assort one half of the plasmid copies to each daughter cell during cell division. This can be achieved directly by partitioning plasmid copies through a mechanism reminiscent of eukaryotic mitosis.
Guynet, Catherine, Cruz, Fernando de la
core   +4 more sources

Plasmid partition and incompatibility – the focus shifts [PDF]

open access: yesMolecular Microbiology, 2007
The mitotic apparatus that a plasmid uses to ensure its stable inheritance responds to the appearance of an additional copy of the plasmid's centromere by segregating it from the pre-existing copies: if the new copy arises by replication of the plasmid ...
Lane, David   +5 more
core   +3 more sources

Plasmid partition: sisters drifting apart. [PDF]

open access: yesEMBO J, 2013
Remarkably little is known about how bacterial chromosomes and their plasmids are partitioned to daughter cells prior to cell division, despite extensive experimentation and bioinformatic analysis. An in vitro study described in the current issue of The EMBO Journal recapitulates many features of plasmid partition in vivo and provides insight into how ...
Sherratt D.
europepmc   +4 more sources

Plasmid stability analysis based on a new theoretical model employing stochastic simulations. [PDF]

open access: yesPLoS ONE, 2017
Here, we present a simple theoretical model to study plasmid stability, based on one input parameter which is the copy number of plasmids present in a host cell.
Olesia Werbowy   +2 more
doaj   +1 more source

Genome Segregation by the Venus Flytrap Mechanism: Probing the Interaction Between the ParF ATPase and the ParG Centromere Binding Protein

open access: yesFrontiers in Molecular Biosciences, 2020
The molecular events that underpin genome segregation during bacterial cytokinesis have not been fully described. The tripartite segrosome complex that is encoded by the multiresistance plasmid TP228 in Escherichia coli is a tractable model to decipher ...
Marisa Caccamo   +5 more
doaj   +1 more source

Fine-structure analysis of the P7 plasmid partition site

open access: yes, 1993
The par region of bacteriophage P7 is responsible for active partition of the P7 plasmid prophage into daughter cells. The cis-acting partition site was defined precisely as a 75-bp sequence that was necessary and sufficient to promote correct ...
Austin, S. J., Hayes, F., Davis, M. A.
core   +10 more sources

Stabilization of the virulence plasmid pSLT of Salmonella Typhimurium by three maintenance systems and its evaluation by using a new stability test

open access: yesFrontiers in Molecular Biosciences, 2016
Certain Salmonella enterica serovars belonging to subspecies I carry low-copy-number virulence plasmids of variable size (50-90 kb). All of these plasmids share the spv operon, which is important for systemic infection.
Damián Lobato-Márquez   +4 more
doaj   +1 more source

Orderly Replication and Segregation of the Four Replicons of Burkholderia cenocepacia J2315. [PDF]

open access: yesPLoS Genetics, 2016
Bacterial genomes typically consist of a single chromosome and, optionally, one or more plasmids. But whole-genome sequencing reveals about ten per-cent of them to be multipartite, with additional replicons which by size and indispensability are ...
Wen-Li Du   +6 more
doaj   +1 more source

Characterization of a Conjugative Multidrug Resistance IncP-2 Megaplasmid, pPAG5, from a Clinical Pseudomonas aeruginosa Isolate

open access: yesMicrobiology Spectrum, 2022
The spread of resistance genes via horizontal plasmid transfer plays a significant role in the formation of multidrug-resistant (MDR) Pseudomonas aeruginosa strains. Here, we identified a megaplasmid (ca.
Meng Li   +6 more
doaj   +1 more source

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