Results 71 to 80 of about 316,175 (228)

Antibiotic resistance in the environment, with particular reference to MRSA [PDF]

, 2008
The introduction of β-lactam antibiotics (penicillins and cephalosporins) in the 1940s and 1950s probably represents the most dramatic event in the battle against infection in human medicine.
Aarestrup, Abraham, Agerso, Agustía, Anthonisen, Archer, Armand‐Lefevre, Asensio, Aubry‐Damon, Baptiste, Bass, Berg, Berghash, Bernabé, Biberstein, Boag, Bonnet, Boxall, Boyle‐Vavra, Briggs, Brinas, Brinas, Brinas, Burd, Burd, Burrus, Busato, Cefai, Chapin, Chee‐Sanford, Chen, Coello, Coffey, Couto, Couto, Cove, Dar, Daum, Davidson, De Liguoro, de Neeling, De Oliveira, Decousser, Devriese, Dingwell, Dunny, Eady, Ensor, Erskine, Fanaro, Fluit, Fox, Freter, Gaze, Gentilini, Germida, Gibbs, Gill, Golet, Gotz, Griggs, Guler, Halbert, Hall, Hamscher, Hansen‐Nord, Hanssen, Hanssen, Hardy, Hartman, Hasman, Hawes, Hawkey, Henriques, Herold, Heuer, Heuer, Hiramatsu, Hoekstra, Hollander, Holmes, Huijsdens, Hutchison, Ito, Ito, Jensen, Kapur, Katayama, Kirby, Kloos, Kummerer, Kuroda, Lee, Lee, Leverstein‐van Hall, Levy, Levy, Lilenbaum, Lindsay, Livermore, Lopes, Machado, Mahamoud, Manian, Marangon, McDonnell, Menzies, Mesa, Morales, Nandi, Neely, Nemergut, Nield, Nordmann, Owen, Owens, Partridge, Patel, Paulsen, Peacock, Pengov, Piddock, Piddock, Pirnay, Poirel, Poirel, Poirel, Poirel, Rahme, Raviglione, Recchia, Roberson, Robicsek, Rodriguez, Sapkota, Sasatsu, Sato, Sato, Segal, Seguin, Shea, Shiraki, Shukla, Sidhu, Sidhu, Singer, Smalla, Smit, Smith, Sorum, Stokes, Tennstedt, Tiemersma, Tikofsky, Tomlin, Top, Turtura, Turutoglu, van Den Bogaard, van den Bogaard, van Duijkeren, van Duijkeren, Vengust, Voss, Waldron, Weese, Weese, Weese, Weigel, White, Witte, Witte   +171 more
core   +1 more source

Enzymatic synthesis of bioactive quinolones and (thio)coumarins by fungal type III polyketide synthases

The FEBS Journal, EarlyView.
Quinolones are valuable scaffolds for drug discovery but are rare in nature. Here, we show that two fungal enzymes, AthePKS and FerePKS, can generate 2‐quinolones and two additional heteroaromatic scaffolds. Using AthePKS, we designed an artificial enzymatic cascade towards an antimicrobial quinolone from a simple precursor and implemented it in E ...
Nika Sokolova, Angelina Osipyan, Lili Zhang, Matthew R. Groves, Sandy Schmidt, Kristina Haslinger   +5 more
wiley   +1 more source

Bacterial plasmid-mediated quinolone resistance genes in aquatic environments in China

Scientific Reports, 2017
Emerging antimicrobial resistance is a major threat to human’s health in the 21st century. Understanding and combating this issue requires a full and unbiased assessment of the current status on the prevalence of antimicrobial resistance genes and their ...
Lei Yan, Dan Liu, Xin-Hua Wang, Yunkun Wang, Bo Zhang, Mingyu Wang, Hai Xu   +6 more
semanticscholar   +1 more source

Detection of plasmid-mediated quinolone resistance determinants and qnrS expression in Enterobacteriaceae clinical isolates

Journal of Infection in Developing Countries, 2014
Introduction: Rapid dissemination of plasmid-mediated quinolone resistance (PMQR) has been reported in clinical isolates. Methodology: A total of 149 clinical isolates of Enterobacteriaceae were collected in Beijing and screened for PMQR genes ...
Xiaobing Jiang, Jun Li, Yunshan Zhang, He Yan, Yuxiao Wang, Lei Shi, Lijun Zhou   +6 more
doaj   +1 more source

Extended-Spectrum-Beta-Lactamases, AmpC Beta-Lactamases and Plasmid Mediated Quinolone Resistance in Klebsiella spp. from Companion Animals in Italy [PDF]

, 2014
We report the genetic characterization of 15 Klebsiella pneumoniae (KP) and 4 isolates of K. oxytoca (KO) from clinical cases in dogs and cats and showing extended-spectrum cephalosporin (ESC) resistance.
A Briales, A Carattoli, A Carattoli, A Coelho, A García-Fernández, A García-Fernández, Alessia Franco, AM Hujer, Antonio Battisti, AT Vo, Aurora García-Fernández, Axel Cloeckaert, B Périchon, C Fontana, C Fontana, C Mammina, C Mammina, CH Park, Christina Aaby Svendsen, D Boccia, D Jonas, DE Roberts, DL Paterson, E Miró, E Voulgari, Fabiola Feltrin, FJ Pérez-Pérez, G Arlet, Gessica Cordaro, J Ma, J Yang, JB Nielsen, KH Roh, L Diancourt, L Hidalgo, L Poirel, L Villa, LM Cavaco, LM Cavaco, M Haenni, M Lavollay, M Österblad, P Roy Chowdhury, R Durmaz, R Migliavacca, R Podschun, Raniero Lorenzetti, Rene S. Hendriksen, S Lavilla, SA Jemima, Serena Lorenzetti, T Frank, T Ode, V Cattoir, Valentina Donati, VL Yu, WC Ko, Y Pfeifer, Y Qi   +58 more
core   +2 more sources

Pathogenicity and Antimicrobial‐Resistance Profiles of Escherichia coli Isolated From Faeces of Tibetan Pigs Reared Under Intensive Conditions

Veterinary Medicine and Science, Volume 12, Issue 3, May 2026.
Tibetan pig farms host diverse Escherichia coli strains that resist multiple antibiotics and carry important disease genes, such as astA. These traits jump easily between bacterial groups, marking intensive pig production as a key reservoir and signalling the need for integrated animal–human surveillance and more careful antibiotic use.
Runbo Luo, Lihong Zhang, Kexin Li, Yanan Zhong, Peng Shang, Suolang Sizhu, Md. F. Kulyar, Ruibing Cao   +7 more
wiley   +1 more source

Establishment of multiplex PCR for detection of genes related to Quinolone resistance

Vietnam Journal of Science, Technology and Engineering, 2018
Background/aims: It has been shown that quinolone resistance arises due to mutations in the quinolone resistance-determining regions of the drug targets.
Ngo Tat Trung, Dao Thanh Quyen, Phan Quoc Hoan, Thirumalaisamy P.P. Velavan, Le Huu Song   +4 more
doaj   +1 more source

Genomic characterization of antibiotic resistant Escherichia coli isolated from domestic chickens in Pakistan [PDF]

, 2019
Poultry husbandry is important for the economic health of Pakistan, but the Pakistani poultry industry is negatively impacted by infections ...
Abbas, Muhammad Athar, Ali Malik, Akbar, Ali, Naeem, Burnham, Carey-Ann D, D\u27Souza, Alaric W, Dantas, Gautam, Ferreiro, Aura, Potter, Robert F, Rafique, Muhammad, Rahim, Abdul, Siddique, Naila, Wallace, Meghan A   +11 more
core   +1 more source

Bacteremia caused by an Acinetobacter junii strain harboring class 1 integron and diverse DNA mobile elements [PDF]

, 2014
INTRODUCTION: Infections caused by Acinetobacter junii are rarely reported. However, some outbreaks of septicemia in neonates and pediatric oncology patients, as well as meningitis, peritonitis, and ocular infection have been described.
Almuzara, Marisa, Centron, Daniela, Neumann, Gabriela, Pallone, Elida Carmen, Ramirez, Maria Soledad, Traglia, German Matias, Tuduri, Alicia, Vilacoba, Elisabet   +7 more
core   +1 more source

Highly Resolved Community Sewage Metagenomics Unveiling Landscape and Transmission Patterns of Antibiotic Resistome in Hong Kong Populations

Advanced Science, Volume 13, Issue 20, 9 April 2026.
A large‐scale, high‐resolution antimicrobial resistance (AMR) surveillance in Hong Kong community sewage combining short‐ and long‐read sequencing. The resistome profile is comprehensively characterized, and this upstream sampling strategy demonstrated superiority in reflecting the human gut resistome.
Jiahui Ding, Mengying Wang, Xiaoqing Xu, Dou Wang, Xi Chen, Shuxian Li, Xiawan Zheng, You Che, Yu Deng, Tommy T. Y. Lam, Liguan Li, Tong Zhang   +11 more
wiley   +1 more source