Results 51 to 60 of about 18,160 (210)

Integrating One Health to Mitigate the Emergence and Spread of Antimicrobial Resistance in Livestock and Aquaculture

Animal Research and One Health, EarlyView.
Antimicrobial resistance (AMR) is an escalating global threat driven by antimicrobial use in aquaculture and livestock. Resistant pathogens and genes can spread across humans, animals, and the environment through interconnected ecosystems. Using a One Health approach, this review emphasizes antimicrobial stewardship, regulatory strengthening, enhanced ...
Mir Mohammad Ali, Delower Hossain, Ridwan Olamilekan Adesola, Anum Hanif, Shamsaldeen Ibrahim Saeed, Muhammad Abdul Mannan, Anoar Jamai Masroure, Kazi Estieque Alam, Md Kamal Hossain, Sabiha Zarin Tasnim Bristi, Md Jisan Ahmed   +10 more
wiley   +1 more source

Mutational Diversity in the Quinolone Resistance-Determining Regions of Type-II Topoisomerases of Salmonella Serovars

Antibiotics, 2021
Quinolone resistance in bacterial pathogens has primarily been associated with mutations in the quinolone resistance-determining regions (QRDRs) of bacterial type-II topoisomerases, which are DNA gyrase and topoisomerase IV. Depending on the position and
Aqsa Shaheen, Anam Tariq, Mazhar Iqbal, Osman Mirza, Abdul Haque, Thomas Walz, Moazur Rahman   +6 more
doaj   +1 more source

Detection of plasmid-mediated quinolone resistance genes in clinical isolates of Enterobacter spp. in Spain [PDF]

, 2009
We have studied by PCR and DNA sequencing the presence of the qnrA, qnrB, qnrS, aac(6′)-Ib-cr, qepA, intI1, and ISCR1 genes in 200 clinical isolates of Enterobacter cloacae (n = 153) and E.
Agüero, J., Calvo, Jorge, Martínez Martínez, Luis, Pascual Hernández, Álvaro, Rodríguez Martínez, José Manuel, Francia, M. V., Cano, María Elicier, Velasco Ramírez, María del Carmen   +7 more
core   +1 more source

Genomic Insights Into Spatiotemporal Dynamics of Acquired Azithromycin Resistance Genes in Salmonella Strains Worldwide

Food Safety and Health, EarlyView.
ABSTRACT Azithromycin has been used for clinical invasive infections caused by fluoroquinolone‐ and third‐generation cephalosporin‐resistant Salmonella, and mass drug administration with azithromycin has been used to reduce under‐5 mortality in children in some countries.
Yuhang Pei, Mengqi Qu, Ziru Yang, Xuebin Xu, Yanan Wang   +4 more
wiley   +1 more source

Broader Distribution of Plasmid-Mediated Quinolone Resistance in the United States [PDF]

Antimicrobial Agents and Chemotherapy, 2005
ABSTRACT The plasmid-encoded quinolone resistance gene qnrA confers low-level quinolone resistance, facilitating selection of higher-level resistance. Epidemiologic surveys for qnrA were extended to isolates of Enterobacter spp. and to quinolone-susceptible
A, Robicsek, D F, Sahm, J, Strahilevitz, G A, Jacoby, D C, Hooper   +4 more
openaire   +2 more sources

Potent monoclonal antibodies against multidrug‐resistant hypervirulent Klebsiella pneumoniae

Interdisciplinary Medicine, EarlyView.
A novel immunization strategy using a low‐virulence, multidrug‐resistant strain yields synergistic monoclonal antibodies against hypervirulent Klebsiella pneumoniae. These antibodies provide cross‐serotype protection through a dual‐mechanism of pathogen clearance and immunomodulation, offering a promising non‐antibiotic therapeutic for resistant ...
Yushan Jiang, Zhuolin Li, Yang Yang, Zihan He, Tyuji Hoshino, Vladislav Victorovich Khrustalev, Qing Zhu, Weiling Wu, Wei Zhao, Chenguang Shen, Shi Ouyang   +10 more
wiley   +1 more source

Phenotypic and Genotypic Characterization of Multidrug-Resistant Enterobacter hormaechei Carrying qnrS Gene Isolated from Chicken Feed in China

Microbiology Spectrum, 2022
Multidrug resistance (MDR) in Enterobacteriaceae including resistance to quinolones is rising worldwide. The plasmid-mediated quinolone resistance (PMQR) gene qnrS is prevalent in Enterobacteriaceae. However, the qnrS gene is rarely found in Enterobacter
Zhengzheng Cao, Luqing Cui, Quan Liu, Fangjia Liu, Yue Zhao, Kaixuan Guo, Tianyu Hu, Fan Zhang, Xijing Sheng, Xiangru Wang, Zhong Peng, Menghong Dai   +11 more
doaj   +1 more source

qnrB , Another Plasmid-Mediated Gene for Quinolone Resistance [PDF]

Antimicrobial Agents and Chemotherapy, 2006
ABSTRACT A novel plasmid-mediated quinolone resistance gene, qnrB , has been discovered in a plasmid encoding the CTX-M-15 β-lactamase from a Klebsiella pneumoniae strain isolated in South India. It has less than 40% amino acid identity with the original qnr (
George A, Jacoby, Kelley E, Walsh, Debra M, Mills, Victoria J, Walker, Herin, Oh, Ari, Robicsek, David C, Hooper   +6 more
openaire   +2 more sources

Assessment of a phenotypic algorithm to detect plasmid-mediated quinolone resistance in Enterobacteriaceae

, 2016
Quinolone resistance in Gram-negative bacteria is the result of mutations in the quinolone resistance-determining region (QRDR) in chromosomally located genes encoding type II topoisomerases and, to a lesser extent, altered permeability. Plasmid-mediated
Polo Padillo, Juan, Díaz de Alba, Paula, Chamizo López, Francisco Javier, Pascual Hernández, Álvaro, Rodríguez Martínez, José Manuel, López Cerero, Lorena   +5 more
core   +1 more source

Biosurfactant production by Pseudomonas aeruginosa isolated from mining waste: From genomic analysis to development of a polymeric composite for removal of hexavalent chromium

Polymer International, EarlyView.
Biosurfactant was produced by Pseudomonas aeruginosa using andiroba waste from Amazonia. A biosurfactant–alginate composite (Alg/BioS) was successfully synthesized via ionotropic gelation, and achieved up to 70% Cr6+ removal from water. Abstract Environmental contamination by heavy metals represents a significant challenge due to their persistence in ...
Paulo Diniz Austriaco, Emilly Cruz da Silva, Glenda Sores Gomes, Joane Almeida Alves, Amanda Vidal, Leandro Argolo, Rafaela Ribeiro, Luciana Souza, José Augusto Pires Bitencourt, Leonardo Brasil Felipe, Leonie Asfora Sarubbo, Sidnei Cerqueira dos Santos   +11 more
wiley   +1 more source