Origin of Plasmid-Mediated Quinolone Resistance Determinant QnrA [PDF]
ABSTRACT Plasmid-mediated resistance to quinolones is increasingly reported in studies of Enterobacteriaceae . Using a PCR-based strategy, a series of gram-negative species were screened for qnrA -like genes.
Laurent, Poirel +4 more
openaire +2 more sources
Interaction of the plasmid-encoded quinolone resistance protein QnrB19 with Salmonella Typhimurium DNA gyrase [PDF]
Background: Plasmid-encoded quinolone resistance protein Qnr is an important factor in bacterial resistance to quinolones. Qnr interacts with DNA gyrase and reduces susceptibility to quinolones.
Orasa Suthienkul +13 more
core +1 more source
Quinolones have been extensively used for treatment of a variety of invasive and systemic infections of salmonellosis. Widespread use of these agents has been associated with the emergence and dissemination of quinolone-resistant pathogens. The quinolone
Ata, Zafer +2 more
core +2 more sources
Distribution of Plasmid mediated quinolone resistance genes.
Distribution of Plasmid mediated quinolone resistance genes.
Ankita Das (165802) +2 more
core +1 more source
HOW DOES QUINOLONES ANTIBOTIC RESISTANCE DEVELOP? [PDF]
The quinolone antibiotics arose in the early 1960s, with the first example having a narrow spectrum of activity with unfavourable pharmacokinetics. Over time, the development of new quinolone antibiotics has led to improved equivalents with an expanded ...
Sherine Aly +4 more
doaj +1 more source
Extensive DNA mimicry by the ArdA anti-restriction protein and its role in the spread of antibiotic resistance [PDF]
The ardA gene, found in many prokaryotes including important pathogenic species, allows associated mobile genetic elements to evade the ubiquitous Type I DNA restriction systems and thereby assist the spread of resistance genes in bacterial populations ...
Blakely, Garry W. +13 more
core +1 more source
Investigation of the Frequency of Plasmid-Dependent Quinolone Resistance Genes in Klebsiella Pneumoniae, Pseudomonas Aeruginosa and Escherichia Coli Isolated from Surgical Site Infections [PDF]
Background & aim: In recent years, the rate of antibiotic resistance has been increasing which has led to the limitation of ways to control hospital infections (especially surgical site infections) and accurate treatment options.
M Gholam nezhad +5 more
doaj +1 more source
PLASMID MEDIATED RESISTANCE TO QUINOLONES IN SALMONELLA
Plasmid mediated resistance to quinolones in Salmonella enterica is briefly presented. World wide spread of qnr determinants is evident, indicating the necessity for prudent use of antimicrobials in human and veterinary medicine. In discovering plasmid mediated resistance to quinolones antimicrobial resistance monitoring for β-lactam antibiotics is ...
Velhner, Maja +5 more
openaire +3 more sources
Inhibition of R-plasmid transfer in Escherichia coli by 4-quinolones [PDF]
Inhibition of transfer of four conjugative R plasmids by ciprofloxacin, enoxacin, norfloxacin, ofloxacin, and pipemidic acid was investigated in an Escherichia coli mating system. The absolute concentrations needed for inhibition of conjugation varied from 0.12 microgram/ml for ciprofloxacin to 16 micrograms/ml for pipemidic acid, but the relationship ...
J, Weisser, B, Wiedemann
openaire +2 more sources
Presence of plasmid-mediated quinolone resistance in klebsiella pneumoniae isolates possessing blaKPC in the United States [PDF]
The presence of plasmid-mediated quinolone resistance genes [i.e., qnrA, qnrB, qnrS, aac(6')-Ib-cr, and qepA] was evaluated among 42 bla(KPC)-containing Klebsiella pneumoniae isolates collected in the eastern United States.
Hutton, Rebecca A. +14 more
core +1 more source

