Results 21 to 30 of about 316,175 (228)

Mechanisms of quinolone resistance and implications for human and animal health [PDF]

Veterinarski Glasnik, 2010
Quinolone antibiotics have been widely used in human and veterinary medicine. This has caused the development of resistance and difficulties in the treatment of complicated bacterial infections in humans.
Velhner Maja, Kozoderović Gordana, Jelesić Zora, Stojanov Igor, Ratajac Radomir, Stojanović Dragica   +5 more
doaj   +1 more source

Shigella sonnei genome sequencing and phylogenetic analysis indicate recent global dissemination from Europe [PDF]

, 2012
Shigella are human-adapted Escherichia coli that have gained the ability to invade the human gut mucosa and cause dysentery1,2, spreading efficiently via low-dose fecal-oral transmission3,4. Historically, S.
A Mutreja, A Nastasi, A Saeed, A Stamatakis, AJ Drummond, Andrew Kitchen, D Cohen, D Genobile, DA Sack, Derek J Brown, Derek J Pickard, DK Karaolis, Dong Wook Kim, DR Zerbino, E Paradis, Edward C Holmes, F Yang, François-Xavier Weill, G Greub, G Morelli, GM Pupo, Gordon Dougan, H Li, H Li, H Vinh, H Vinh, H Vinh, HC Lewis, HJ Jeong, HL DuPont, J Parker, J Tang, J Winiecka-Krusnell, Jeremy J Farrar, JG Shepherd, John E Coia, Julian Parkhill, Jun Yu, Kathryn E Holt, KE Holt, KL Kotloff, LL Van de Verg, M Touchon, Nicholas R Thomson, PJ Sansonetti, R Ranjbar, RK Aziz, RW Kaminski, S Kurtz, Seon Young Choi, SR Harris, Stephen Baker, Su Hee Kim, T Shimada, Vartul Sangal, Wanderley D da Silveira   +55 more
core   +4 more sources

The phenazine pyocyanin is a terminal signalling factor in the quorum sensing network of Pseudomonas aeruginosa [PDF]

, 2006
Certain members of the fluorescent pseudomonads produce and secrete phenazines. These heterocyclic, redox-active compounds are toxic to competing organisms, and the cause of these antibiotic effects has been the focus of intense research efforts.
Dietrich, Lars E. P., Newman, Dianne K., Petersen, Ashley, Price-Whelan, Alexa, Whiteley, Marvin   +4 more
core   +1 more source

EVALUATION OF PLASMID-MEDIATED QUINOLONE RESISTANCE ASSOCIATED WITH THE QNR GENES IN CLINICAL ISOLATES OF SHIGELLA SPP. IN BAGHDAD

The Iraqi Journal of Medical Sciences, 2016
Background:Although quinolone resistance results mostly from chromosomal mutations in Enterobacteriaceae, it may also be mediated by plasmid-encoded qnr determinants. Shigella harboring the novel qnr plasmid-mediated mechanism of quinolone resistance has
Thanaa R. Abdulrahman, Qudus W. Jamal, Wurood A. Kadhim, Sabah A. Belal   +3 more
doaj   +4 more sources

Interaction of the plasmid-encoded quinolone resistance protein QnrB19 with Salmonella Typhimurium DNA gyrase.

Journal of Infection and Chemotherapy, 2020
BACKGROUND Plasmid-encoded quinolone resistance protein Qnr is an important factor in bacterial resistance to quinolones. Qnr interacts with DNA gyrase and reduces susceptibility to quinolones. The gene qnr likely spreads rapidly among Enterobacteriaceae
Ruttana Pachanon, Kentaro Koide, S. Kongsoi, C. Nakajima, T. Kapalamula, O. Suthienkul, Yasuhiko Suzuki   +6 more
semanticscholar   +1 more source

Quinolone resistance mechanisms among extended-spectrum beta-lactamase (ESBL) producing Escherichia coli isolated from rivers and lakes in Switzerland. [PDF]

PLoS ONE, 2014
Sixty extended-spectrum β-lactamase (ESBL)-producing Escherichia coli isolated from rivers and lakes in Switzerland were screened for individual strains additionally exhibiting a reduced quinolone susceptibility phenotype.
Katrin Zurfluh, Helga Abgottspon, Herbert Hächler, Magdalena Nüesch-Inderbinen, Roger Stephan   +4 more
doaj   +1 more source

Clerocidin selectively modifies the gyrase-DNA gate to induce irreversible and reversible DNA damage [PDF]

, 2008
Clerocidin (CL), a microbial diterpenoid, reacts with DNA via its epoxide group and stimulates DNA cleavage by type II DNA topoisomerases. The molecular basis of CL action is poorly understood.
Binaschi, Borgnetto, Brown, Cambau, Champoux, Corbett, Corbett, Ferrero, Fisher, Gatto, Higgins, Kawada, L. M. Fisher, M. Dias, M. Palumbo, Marians, Maxam, McCullough, Mizuuchi, Morrison, Pan, Pan, Pan, Pan, Pan, Peden, Pozzi, Richter, Richter, Richter, Shea, X. S. Pan, Yague, Yoshida, Zechiedrich   +34 more
core   +1 more source

Transduction as a Potential Dissemination Mechanism of a Clonal qnrB19-Carrying Plasmid Isolated From Salmonella of Multiple Serotypes and Isolation Sources

Frontiers in Microbiology, 2019
Antimicrobial resistance is an increasing problem worldwide, and Salmonella spp. resistance to quinolone was classified by WHO in the high priority list.
Andrea I. Moreno-Switt, Andrea I. Moreno-Switt, David Pezoa, Vanessa Sepúlveda, Iván González, Dácil Rivera, Patricio Retamal, Paola Navarrete, Paola Navarrete, Angélica Reyes-Jara, Magaly Toro   +10 more
doaj   +1 more source

Detection of plasmid-mediated qnr genes among the quinolone-resistant Escherichia coli isolates in Iran

Journal of Infection in Developing Countries, 2014
Introduction: Plasmid-mediated quinolone resistance, which complicates treatment, has been increasingly identified in Escherichia coli isolates worldwide.
Farzaneh Firoozeh, Mohammad Zibaei, Younes Soleimani-Asl   +2 more
doaj   +1 more source

Can we prevent antimicrobial resistance by using antimicrobials better? [PDF]

, 2013
Since their development over 60 years ago, antimicrobials have become an integral part of healthcare practice worldwide. Recently, this has been put in jeopardy by the emergence of widespread antimicrobial resistance, which is one of the major problems ...
Brown, Caron, Cars, Cars, Collignon, Dagan, DiNubile, Drlica, Essack, Fox, Geli, Goren, Gould, Guillemot, Harris, Hurdle, Huttner, Isha, Madurell, Masterton, Michalsen, Mitchison, Mitchison, Molstad, Sharma, Solapure, Talbot, Thomas   +27 more
core   +2 more sources