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Analyses of Plasmids Harbouring Quinolone Resistance Determinants in Enterobacteriaceae Members [PDF]
Polish Journal of Microbiology, 2017 The aim of this study was to explore the plasmid characteristics of eight clinical Enterobacteriaceae strains containing extended broad spectrum beta-lactamases and plasmid-mediated quinolone resistance.
Bayri Erac +4 more
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Plasmid-Mediated Quinolone Resistance Genes in Escherichia coli Strains Isolated from Healthy Dogs [PDF]
Veterinary SciencesKnowledge about the potential roles of pets as reservoirs for plasmid-mediated quinolone resistance is still limited in Türkiye. Thus, in our study, the presence of plasmid-mediated quinolone genes (qnrA, qnrB and qnrS) was examined by multiplex ...
Fatma Kalaycı-Yüksek +4 more
doaj +2 more sources
Plasmid-mediated quinolone resistance – current knowledge and future perspectives [PDF]
Journal of International Medical Research, 2013 Quinolones are a group of antimicrobial agents that were serendipitously discovered as byproducts of the synthesis of chloroquine. Chemical modifications, such as the addition of fluorine or piperazine, resulted in the synthesis of third- and fourth-generation fluoroquinolones, with broad-spectrum antimicrobial actions against aerobic or anaerobic ...
Xizhou, Guan +11 more
exaly +3 more sources
Characterization of plasmid-mediated quinolone resistant genes among uropathogenic Escherichia coli isolates in Bushehr, south of Iran [PDF]
BMC Research NotesObjectives Uropathogenic Escherichia coli (UPEC) is important in urinary tract infection (UTI). Quinolones and fluoroquinolones are broad-spectrum antibiotics for the treatment of UTI, although some of UPEC are resistant to these antibiotics.
Matin Aref +4 more
doaj +2 more sources
PLASMID-MEDIATED QUINOLONE RESISTANCE – PMQR [PDF]
Postępy Mikrobiologii, 2018 Katarzyna Piekarska
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Plasmid-Mediated Quinolone Resistance [PDF]
Microbiology Spectrum, 2014 ABSTRACTThree mechanisms for plasmid-mediated quinolone resistance (PMQR) have been discovered since 1998. Plasmid genesqnrA, qnrB, qnrC, qnrD, qnrS,andqnrVCcode for proteins of the pentapeptide repeat family that protects DNA gyrase and topoisomerase IV from quinolone inhibition.
George A, Jacoby +2 more
openaire +3 more sources
Journal of Pure and Applied Microbiology, 2022 Klebsiella pneumoniae (K. pneumoniae) is an important pathogen associated with various infections. The emergence of antibiotic resistances, such as quinolone resistance and those due to extended-spectrum beta-lactamases (ESBL), reduces the available ...
Marwah M. Bakri
doaj +1 more source
PLoS ONE, 2023 BackgroundAntibiotic resistance has become an enduring threat to human health. This has prompted extensive research to identify the determinants responsible in a bid to fight the spread of resistance and also develop new antibiotics.
Jude Fonbah Leinyuy +3 more
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Antimicrobial Resistance and Infection Control, 2020 Background Quinolones are commonly used for treatment of infections by bacteria of the Enterobacteriaceae family. However, the rising resistance to quinolones worldwide poses a major clinical and public health risk.
Ying Tao +7 more
doaj +1 more source
In vitro plasmid-encoded resistance to quinolones [PDF]
FEMS Microbiology Letters, 2006 The possibility of plasmid-encoded quinolone resistance is explored in two model systems. In the first, increasing amounts of wild-type gyrA allele moderately increased minimum inhibitory concentrations to quinolone antibiotics. In the second model, a mutant gyrA allele encoded by a multicopy plasmid produced a quinolone resistance phenotype upon its ...
J M, Gómez-Gómez +5 more
openaire +2 more sources