Results 31 to 40 of about 18,160 (210)
Elimination of plasmids by new 4-quinolones
Antimicrobial Agents and Chemotherapy, 1985 Nalidixic acid and six of the new 4-quinolones eliminated F'lac and various native R plasmids from Escherichia coli at one half or one quarter the MIC. Four of eight plasmids tested were cured by all derivatives, with frequencies from 10 to 98%. Quinolones did not eliminate all plasmids that were cured by novobiocin, and vice versa.
J, Weisser, B, Wiedemann
openaire +3 more sources
The Iraqi Journal of Medical Sciences, 2016 Background:Although quinolone resistance results mostly from chromosomal mutations in Enterobacteriaceae, it may also be mediated by plasmid-encoded qnr determinants. Shigella harboring the novel qnr plasmid-mediated mechanism of quinolone resistance has
Thanaa R. Abdulrahman +3 more
doaj +4 more sources
Bar plot depicting the distribution of plasmid-mediated quinolone resistance genes.
, 2022 Bar plot depicting the distribution of plasmid-mediated quinolone resistance genes.
Shaheen Akhtar Malik (13021314) +7 more
core +1 more source
Hot-spot consensus of fluoroquinolone-mediated DNA cleavage by gram-negative and gram-positive type II DNA topoisomerases [PDF]
, 2007 Bacterial DNA gyrase and topoisomerase IV are selective targets of fluoroquinolones. Topoisomerase IV versus gyrase and Gram-positive versus Gram-negative behavior was studied based on the different recognition of DNA sequences by topoisomerase ...
GIARETTA G +15 more
core +1 more source
Gut Pathogens, 2021 Non-typhoidal salmonellosis remains a pressing public health problem worldwide. Quinolones, particularly fluoroquinolones, are widely used to treat various infections, including non-typhoidal salmonellosis, which can be a serious illness.
Sohyun Lee +7 more
doaj +1 more source
Frontiers in Microbiology, 2019 Antimicrobial resistance is an increasing problem worldwide, and Salmonella spp. resistance to quinolone was classified by WHO in the high priority list.
Andrea I. Moreno-Switt +10 more
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Quinolone resistance mechanisms among extended-spectrum beta-lactamase (ESBL) producing Escherichia coli isolated from rivers and lakes in Switzerland. [PDF]
PLoS ONE, 2014 Sixty extended-spectrum β-lactamase (ESBL)-producing Escherichia coli isolated from rivers and lakes in Switzerland were screened for individual strains additionally exhibiting a reduced quinolone susceptibility phenotype.
Katrin Zurfluh +4 more
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Plasmid mediated quinolone resistance in Enterobacteriaceae
, 2014 This thesis describes the occurrence of Plasmid Mediated Quinolone Resistance (PMQR) in Salmonella and E. coli from The Netherlands and other European countries. Furthermore, the genetic background of these genes was characterized. Fluoroquinolones are widely used antibiotics in both human and veterinary medicine.
Veldman, K.T. +1 more
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Temporal Appearance of Plasmid-Mediated Quinolone Resistance Genes [PDF]
Antimicrobial Agents and Chemotherapy, 2009 ABSTRACT One hundred fifty AAC(6′)-Ib-positive gram-negative isolates collected between 1981 and 1991 were examined by PCR for the presence of the aac(6 ′ )-Ib-cr variant and other plasmid-mediated quinolone resistance (PMQR) genes. None had the aac(6 ′
George A, Jacoby +4 more
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DNA Gyrase as a Target for Quinolones
Biomedicines, 2023 Bacterial DNA gyrase is a type II topoisomerase that can introduce negative supercoils to DNA substrates and is a clinically-relevant target for the development of new antibacterials. DNA gyrase is one of the primary targets of quinolones, broad-spectrum
Angela C. Spencer, Siva S. Panda
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