Results 11 to 20 of about 1,096,066 (258)
Microbiology and Molecular Biology Reviews, 2010 SUMMARYPlasmids are key vectors of horizontal gene transfer and essential genetic engineering tools. They code for genes involved in many aspects of microbial biology, including detoxication, virulence, ecological interactions, and antibiotic resistance.
Smillie, C. +4 more
openaire +5 more sources
Proceedings of the National Academy of Sciences of the United States of America, 2021 Significance There is great interest in understanding how antibiotic resistance is disseminated by MGEs (i.e., plasmids, insertion sequences, and integrons).
You Che +6 more
semanticscholar +1 more source
Phage-Plasmids Spread Antibiotic Resistance Genes through Infection and Lysogenic Conversion
bioRxiv, 2022 The dissemination of antimicrobial resistance is a major threat to global health. Here, we show that a group of temperate bacterial viruses (phages), termed phage-plasmids, commonly encode different and multiple types of resistance genes of high clinical
E. Pfeifer, R. Bonnin, E. Rocha
semanticscholar +1 more source
Identification of dfrA14 in two distinct plasmids conferring trimethoprim resistance in Actinobacillus pleuropneumoniae [PDF]
, 2015 OBJECTIVES: The objective of this study was to determine the distribution and genetic basis of trimethoprim resistance in Actinobacillus pleuropneumoniae isolates from pigs in England.
Alexander W. Tucker +17 more
core +4 more sources
Cloning vectors for gene delivery, integration and expression in Campylobacter jejuni
BioTechniques, 2022 Campylobacter genetics research is negatively impacted by a shortage of molecular tools for expressing DNA elements. A previous technique coupled an antibiotic resistance gene and its promoter to a gene of interest, inserting this expression unit into a ...
Gaylen A Uhlich +2 more
doaj +1 more source
Reporter constructs with low background activity utilizing the cat gene [PDF]
, 1992 Reporter plasmids utilizing the cat gene for the analysis of promoter and enhancer sequences in vertebrate cells, were constructed. These plasmids minimize the background of transcription derived from cryptic promoters or cryptic regulatory elements ...
Andrea Schmidt +11 more
core +1 more source
Frontiers in Microbiology, 2022 Carbapenemase-producing Enterobacterales (CPE) are considered a major public health issue. In the frame of the EU Harmonized AMR Monitoring program conducted in Italy in 2021, 21 epidemiological units of fattening pigs (6.98%; 95% CI 4.37–10.47%; 21/301)
Virginia Carfora +12 more
doaj +1 more source
Microbiology Spectrum, 2014 ABSTRACT Iteron-containing plasmids are model systems for studying the metabolism of extrachromosomal genetic elements in bacterial cells. Here we describe the current knowledge and understanding of the structure of iteron-containing replicons, the structure of the iteron plasmid encoded replication initiation proteins, and the molecular ...
Igor, Konieczny +3 more
openaire +2 more sources
Analysis of two pheromone-responsive conjugative multiresistance plasmids carrying the novel mobile optrA locus from Enterococcus faecalis [PDF]
, 2019 Background: The acquired optrA gene, which encodes a ribosomal protection protein of the ABC-F family, can confer cross-resistance to linezolid and florfenicol, posing a serious therapeutic challenge to both human and veterinary medicine.
Chen, Yu-Xia +7 more
core +1 more source
Frontiers in Microbiology, 2020 Carbapenemase-producing Enterobacteriaceae are a major threat to global public health. Klebsiella pneumoniae carbapenemase (KPC) is the most commonly identified carbapenemase in the United States and is frequently found on mobile genetic elements ...
Catharine Prussing +9 more
doaj +1 more source