Results 31 to 40 of about 1,080,559 (427)

Toxin-Antitoxin Systems in Clinical Pathogens

open access: yesToxins, 2016
Toxin-antitoxin (TA) systems are prevalent in bacteria and archaea. Although not essential for normal cell growth, TA systems are implicated in multiple cellular functions associated with survival under stress conditions. Clinical strains of bacteria are
Laura Fernández-García   +6 more
doaj   +1 more source

The Distinctive Evolution of orfX Clostridium parabotulinum Strains and Their Botulinum Neurotoxin Type A and F Gene Clusters Is Influenced by Environmental Factors and Gene Interactions via Mobile Genetic Elements

open access: yesFrontiers in Microbiology, 2021
Of the seven currently known botulinum neurotoxin-producing species of Clostridium, C. parabotulinum, or C. botulinum Group I, is the species associated with the majority of human botulism cases worldwide.
Theresa J. Smith   +10 more
doaj   +1 more source

MOB-suite: software tools for clustering, reconstruction and typing of plasmids from draft assemblies

open access: yesMicrobial Genomics, 2018
Large-scale bacterial population genetics studies are now routine due to cost-effective Illumina short-read sequencing. However, analysing plasmid content remains difficult due to incomplete assembly of plasmids. Bacterial isolates can contain any number
James Robertson, John H. E. Nash
semanticscholar   +1 more source

The Secretion of Toxins and Other Exoproteins of Cronobacter: Role in Virulence, Adaption, and Persistence

open access: yesMicroorganisms, 2020
Cronobacter species are considered an opportunistic group of foodborne pathogenic bacteria capable of causing both intestinal and systemic human disease.
Hyein Jang   +14 more
doaj   +1 more source

Rapid compensatory evolution promotes the survival of conjugative plasmids [PDF]

open access: yes, 2016
Conjugative plasmids play a vital role in bacterial adaptation through horizontal gene transfer. Explaining how plasmids persist in host populations however is difficult, given the high costs often associated with plasmid carriage. Compensatory evolution
Brockhurst, Michael A.   +6 more
core   +4 more sources

Enterococcus faecalis an Emerging Microbial Menace in Dentistry-An Insight into the In-Silico Detection of Drug Resistant Genes and Its Protein Diversity [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2018
Introduction: Antimicrobial drug resistance is evolving as a serious threat to mankind due to indiscriminate use of antibiotics and lack of awareness about the mechanisms involved in drug resistance.
Vijayashree J Priyadharsini   +2 more
doaj   +1 more source

Analysis of two pheromone-responsive conjugative multiresistance plasmids carrying the novel mobile optrA locus from Enterococcus faecalis [PDF]

open access: yes, 2019
Background: The acquired optrA gene, which encodes a ribosomal protection protein of the ABC-F family, can confer cross-resistance to linezolid and florfenicol, posing a serious therapeutic challenge to both human and veterinary medicine.
Chen, Yu-Xia   +7 more
core   +1 more source

Parallel compensatory evolution stabilizes plasmids across the parasitism-mutualism continuum [PDF]

open access: yes, 2015
Plasmids drive genomic diversity in bacteria via horizontal gene transfer [1 and 2]; nevertheless, explaining their survival in bacterial populations is challenging [3].
Brockhurst, Michael A.   +4 more
core   +5 more sources

Genomic Surveillance of Ceftriaxone-Resistant Escherichia coli in Western New York Suggests the Extended-Spectrum β-Lactamase blaCTX-M-27 Is Emerging on Distinct Plasmids in ST38

open access: yesFrontiers in Microbiology, 2020
Extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae pose significant treatment and infection prevention challenges. Escherichia coli sequence type (ST) 131 associated with the blaCTX-M-15 gene has been the dominant lineage of ESBL-producing
Heba H. Mostafa   +10 more
doaj   +1 more source

COPLA, a taxonomic classifier of plasmids

open access: yesBMC Bioinformatics, 2020
Plasmids are mobile genetic elements, key in the dissemination of antibiotic resistance, virulence determinants and other adaptive traits in bacteria. Obtaining a robust method for plasmid classification is necessary to better understand the genetics and
S. Redondo-Salvo   +6 more
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy