Results 31 to 40 of about 899,588 (362)

Mobility of Plasmids [PDF]

Microbiology and Molecular Biology Reviews, 2010
SUMMARYPlasmids are key vectors of horizontal gene transfer and essential genetic engineering tools. They code for genes involved in many aspects of microbial biology, including detoxication, virulence, ecological interactions, and antibiotic resistance.
Smillie, C., Garcillan-Barcia, M. P., Francia, M. V., Rocha, Eduardo, de La Cruz, F.   +4 more
openaire   +4 more sources

Draft genome sequence of Pseudomonas moraviensis R28-S [PDF]

, 2014
We report the draft genome sequence of Pseudomonas moraviensis R28-S, isolated from the municipal wastewater treatment plant of Moscow, ID. The strain carries a native mercury resistance plasmid, poorly maintains introduced IncP-1 antibiotic resistance ...
De Gelder, Leen, De Vos, Paul, Hughes, Julie, Hunter, Samual S, Loftie-Eaton, Wesley, Settles, Matthew L, Stragier, Pieter, Top, Eva M, Yano, Hirukazo   +8 more
core   +1 more source

Escherichia coli of sequence type 3835 carrying blaNDM-1, blaCTX-M-15, blaCMY-42 and blaSHV-12 [PDF]

, 2015
New Delhi metallo-β-lactamase (NDM) represents a serious challenge for treatment and public health. A carbapenem-resistant Escherichia coli clinical strain WCHEC13-8 was subjected to antimicrobial susceptibility tests, whole genome sequencing and ...
Feng, Y, McNally, A, Wang, X, Xie, Y, Yang, P, Zong, Z   +5 more
core   +1 more source

Antibiotic resistance begets more resistance: chromosomal resistance mutations mitigate fitness costs conferred by multi-resistant clinical plasmids

Microbiology Spectrum
Plasmids are the primary vectors of horizontal transfer of antibiotic resistance genes among bacteria. Previous studies have shown that the spread and maintenance of plasmids among bacterial populations depend on the genetic makeup of both the plasmid ...
Ramith R. Nair, Dan I. Andersson, Omar M. Warsi   +2 more
doaj   +1 more source

Recovering Escherichia coli Plasmids in the Absence of Long-Read Sequencing Data

Microorganisms, 2021
The incidence of infections caused by multidrug-resistant E. coli strains has risen in the past years. Antibiotic resistance in E. coli is often mediated by acquisition and maintenance of plasmids. The study of E.
Julian A. Paganini, Nienke L. Plantinga, Sergio Arredondo-Alonso, Rob J. L. Willems, Anita C. Schürch   +4 more
doaj   +1 more source

Plasmid-to-plasmid recombination in Haemophilus influenzae [PDF]

Journal of Bacteriology, 1986
No recombination between plasmids was observed after conjugal transfer of a plasmid into a cell carrying another plasmid. Two types of such recombination took place after transformation, one type being Rec+ dependent and suggesting a preferred site of recombination. The other much rarer type was at least partially Rec+ independent.
M, Balganesh, J K, Setlow
openaire   +2 more sources

Sustained gene expression in the retina by improved episomal vectors [PDF]

, 2014
Gene and cellular therapies are nowadays part of therapeutic strategies for the treatment of diverse pathologies. The drawbacks associated with gene therapy-low levels of transgene expression, vector loss during mitosis, and gene silencing-need to be ...
Ana V. Oliveira, Conley S.M., Davis A.A., Gabriela A. Silva, Reinisalo M., Rudolf Haase, Sofia M. Calado, Susana Machado   +7 more
core   +1 more source

Characterization of Four Multidrug Resistance Plasmids Captured from the Sediments of an Urban Coastal Wetland

Frontiers in Microbiology, 2017
Self-transmissible and mobilizable plasmids contribute to the emergence and spread of multidrug-resistant bacteria by enabling the horizontal transfer of acquired antibiotic resistance.
Ryan T. Botts, Brooke A. Apffel, C. J. Walters, Kelly E. Davidson, Ryan S. Echols, Michael R. Geiger, Victoria L. Guzman, Victoria S. Haase, Michal A. Montana, Chip A. La Chat, Jenna A. Mielke, Kelly L. Mullen, Cierra C. Virtue, Celeste J. Brown, Eva M. Top, David E. Cummings   +15 more
doaj   +1 more source

Enterococcus faecalis an Emerging Microbial Menace in Dentistry-An Insight into the In-Silico Detection of Drug Resistant Genes and Its Protein Diversity [PDF]

Journal of Clinical and Diagnostic Research, 2018
Introduction: Antimicrobial drug resistance is evolving as a serious threat to mankind due to indiscriminate use of antibiotics and lack of awareness about the mechanisms involved in drug resistance.
Vijayashree J Priyadharsini, AS Smilinegirija, A Paramasivam   +2 more
doaj   +1 more source

Plasmid Biopharmaceuticals

Microbiology Spectrum, 2014
ABSTRACTPlasmids are currently an indispensable molecular tool in life science research and a central asset for the modern biotechnology industry, supporting its mission to produce pharmaceutical proteins, antibodies, vaccines, industrial enzymes, and molecular diagnostics, to name a few key products.
Duarte Miguel F, Prazeres, Gabriel A, Monteiro   +1 more
openaire   +2 more sources