Results 31 to 40 of about 1,080,559 (427)
Toxin-Antitoxin Systems in Clinical Pathogens
Toxin-antitoxin (TA) systems are prevalent in bacteria and archaea. Although not essential for normal cell growth, TA systems are implicated in multiple cellular functions associated with survival under stress conditions. Clinical strains of bacteria are
Laura Fernández-García+6 more
doaj +1 more source
Of the seven currently known botulinum neurotoxin-producing species of Clostridium, C. parabotulinum, or C. botulinum Group I, is the species associated with the majority of human botulism cases worldwide.
Theresa J. Smith+10 more
doaj +1 more source
Large-scale bacterial population genetics studies are now routine due to cost-effective Illumina short-read sequencing. However, analysing plasmid content remains difficult due to incomplete assembly of plasmids. Bacterial isolates can contain any number
James Robertson, John H. E. Nash
semanticscholar +1 more source
Cronobacter species are considered an opportunistic group of foodborne pathogenic bacteria capable of causing both intestinal and systemic human disease.
Hyein Jang+14 more
doaj +1 more source
Rapid compensatory evolution promotes the survival of conjugative plasmids [PDF]
Conjugative plasmids play a vital role in bacterial adaptation through horizontal gene transfer. Explaining how plasmids persist in host populations however is difficult, given the high costs often associated with plasmid carriage. Compensatory evolution
Brockhurst, Michael A.+6 more
core +4 more sources
Enterococcus faecalis an Emerging Microbial Menace in Dentistry-An Insight into the In-Silico Detection of Drug Resistant Genes and Its Protein Diversity [PDF]
Introduction: Antimicrobial drug resistance is evolving as a serious threat to mankind due to indiscriminate use of antibiotics and lack of awareness about the mechanisms involved in drug resistance.
Vijayashree J Priyadharsini+2 more
doaj +1 more source
Analysis of two pheromone-responsive conjugative multiresistance plasmids carrying the novel mobile optrA locus from Enterococcus faecalis [PDF]
Background: The acquired optrA gene, which encodes a ribosomal protection protein of the ABC-F family, can confer cross-resistance to linezolid and florfenicol, posing a serious therapeutic challenge to both human and veterinary medicine.
Chen, Yu-Xia+7 more
core +1 more source
Parallel compensatory evolution stabilizes plasmids across the parasitism-mutualism continuum [PDF]
Plasmids drive genomic diversity in bacteria via horizontal gene transfer [1 and 2]; nevertheless, explaining their survival in bacterial populations is challenging [3].
Brockhurst, Michael A.+4 more
core +5 more sources
Extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae pose significant treatment and infection prevention challenges. Escherichia coli sequence type (ST) 131 associated with the blaCTX-M-15 gene has been the dominant lineage of ESBL-producing
Heba H. Mostafa+10 more
doaj +1 more source
COPLA, a taxonomic classifier of plasmids
Plasmids are mobile genetic elements, key in the dissemination of antibiotic resistance, virulence determinants and other adaptive traits in bacteria. Obtaining a robust method for plasmid classification is necessary to better understand the genetics and
S. Redondo-Salvo+6 more
semanticscholar +1 more source