Results 41 to 50 of about 833,514 (313)

PLSDB: a resource of complete bacterial plasmids

Nucleic Acids Res., 2018
The study of bacterial isolates or communities requires the analysis of the therein included plasmids in order to provide an extensive characterization of the organisms. Plasmids harboring resistance and virulence factors are of especial interest as they
Valentina Galata, Tobias Fehlmann, C. Backes, A. Keller   +3 more
semanticscholar   +1 more source

A food poisoning caused by ST7 Staphylococcal aureus harboring sea gene in Hainan province, China

Frontiers in Microbiology, 2023
ST7 Staphylococcus aureus is highly prevalent in humans, pigs, as well as food in China; however, staphylococcal food poisoning (SFP) caused by this ST type has rarely been reported. On May 13, 2017, an SFP outbreak caused by ST7 S.
Yahui Guo, Yahui Guo, Yahui Guo, Xiaojie Yu, Jixiao Wang, De Hua, Yuanhai You, Qingbo Wu, Qinglong Ji, Jianzhong Zhang, Liefei Li, Yuan Hu, Zhonghui Wu, Xiaoyue Wei, Lianqun Jin, Fanliang Meng, Yuhua Yang, Xiaofeng Hu, Lijin Long, Songnian Hu, Heyuan Qi, Juncai Ma, Juncai Ma, Wenwen Bei, Xiaomei Yan, Haibin Wang, Haibin Wang, Zilong He   +27 more
doaj   +1 more source

Replicon-Based Typing of IncI-Complex Plasmids, and Comparative Genomics Analysis of IncIγ/K1 Plasmids

Frontiers in Microbiology, 2019
IncI-complex plasmids can be divided into seven subgroups IncI1, IncI2, IncIγ, IncB/O, IncK1, IncK2, and IncZ. In this study, a replicon-based scheme was proposed for typing IncI-complex plasmids into four separately clustering subgroups IncI2, IncI1/B/O,
Defu Zhang, Defu Zhang, Defu Zhang, Defu Zhang, Yuzong Zhao, Yuzong Zhao, Yuzong Zhao, Yuzong Zhao, Jiao Feng, Lingfei Hu, Xiaoyuan Jiang, Zhe Zhan, Huiying Yang, Wenhui Yang, Bo Gao, Jinglin Wang, Jianrong Li, Jianrong Li, Jianrong Li, Zhe Yin, Dongsheng Zhou   +20 more
doaj   +1 more source

Mobile genetic elements carrying aminoglycoside resistance genes in Acinetobacter baumannii isolates belonging to global clone 2

Frontiers in Microbiology, 2023
Aminoglycosides are used to treat infections caused by carbapenem-resistant Acinetobacter baumannii (CRAB) strains. However, resistance to aminoglycosides has increased remarkably in the last few years.
Ghazal Naderi, Malihe Talebi, Roghayeh Gheybizadeh, Arash Seifi, Sedigheh Ghourchian, Mohammad Rahbar, Alireza Abdollahi, Abdolhossein Naseri, Parisa Eslami, Masoumeh Douraghi   +9 more
doaj   +1 more source

Fitness Costs of Plasmids: a Limit to Plasmid Transmission

Microbiology spectrum, 2017
Plasmids mediate the horizontal transmission of genetic information between bacteria, facilitating their adaptation to multiple environmental conditions.
Á. S. Millán, R. MacLean, Fernando Baquero, T. Coque, Á. S. Millán   +4 more
semanticscholar   +1 more source

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

FEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp, Katharina Rataj, Stefanie König, Marcia E. Newcomer, Oliver Werz, Ulrike Garscha   +5 more
wiley   +1 more source

Pangenome-level analysis of nucleoid-associated proteins in the Acidithiobacillia class: insights into their functional roles in mobile genetic elements biology

Frontiers in Microbiology, 2023
Mobile genetic elements (MGEs) are relevant agents in bacterial adaptation and evolutionary diversification. Stable appropriation of these DNA elements depends on host factors, among which are the nucleoid-associated proteins (NAPs).
Simón Beard, Simón Beard, Ana Moya-Beltrán, Ana Moya-Beltrán, Danitza Silva-García, Cesar Valenzuela, Tomás Pérez-Acle, Tomás Pérez-Acle, Tomás Pérez-Acle, Alejandra Loyola, Alejandra Loyola, Raquel Quatrini, Raquel Quatrini   +12 more
doaj   +1 more source

The carboxylate “gripper” of the substrate is critical for C‐4 stereo‐inversion by UDP‐glucuronic acid 4‐epimerase

FEBS Letters, EarlyView.
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg, Laura De Cnop, Bernd Nidetzky   +2 more
wiley   +1 more source

The thioredoxin‐like and one glutaredoxin domain are required to rescue the iron‐starvation phenotype of HeLa GLRX3 knock out cells

FEBS Letters, EarlyView.
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt, Manuela Gellert, Finja Zelms, Sander Bekeschus, Christopher Horst Lillig   +4 more
wiley   +1 more source

Global phylogenetic analysis of Escherichia coli and plasmids carrying the mcr-1 gene indicates bacterial diversity but plasmid restriction

Scientific Reports, 2017
To understand the dynamics behind the worldwide spread of the mcr-1 gene, we determined the population structure of Escherichia coli and of mobile genetic elements (MGEs) carrying the mcr-1 gene. After a systematic review of the literature we included 65
S. Matamoros, Jarne M. van Hattem, M. Arcilla, Niels Willemse, D. Melles, J. Penders, T. N. Vinh, Ngo Thi Hoa, M. Bootsma, P. V. van Genderen, A. Goorhuis, M. Grobusch, Nicky Molhoek, A. O. Oude Lashof, E. Stobberingh, H. Verbrugh, M. D. de Jong, C. Schultsz   +17 more
semanticscholar   +1 more source