Results 41 to 50 of about 1,080,559 (427)
Antiparallel plasmid-plasmid pairing may control P1 plasmid replication. [PDF]
The copy number of the P1 plasmid replicon is stringently controlled, giving only one or two copies per newborn cell. Control is achieved by the action of the copy-control locus incA, which contains nine repeats of the 19-basepair binding site for the plasmid-encoded initiator protein RepA.
Ann L. Abeles, Stuart Austin
openaire +3 more sources
Yersinia pestis belongs to those pathogenic bacteria which produce lipopolysaccharide (LPS) having the function of a toxin. In order to make a toxic effect the polymer must be separated from the cell outer membrane and presented to the immunocompetent ...
V. I. Tynyanova+3 more
doaj +1 more source
Mobile elements—plasmids and phages—are important components of microbial function and evolution via traits that they encode and their capacity to shuttle genetic material between species. We here report the unusually rich array of mobile elements within
Crystal L. Frost+6 more
doaj +1 more source
Tigecycline-resistant Escherichia coli ST761 carrying tet(X4) in a pig farm, China
This study aimed to investigate the prevalence and characterization of tet(X4) in Escherichia coli isolates from a pig farm in Shanghai, China, and to elucidate tet(X4) dissemination mechanism in this swine farm. Forty-nine (80.33%) E.
Jing Wang+13 more
doaj +1 more source
Noise enhanced persistence in a biochemical regulatory network with feedback control [PDF]
We find that discrete noise of inhibiting (signal) molecules can greatly delay the extinction of plasmids in a plasmid replication system: a prototypical biochemical regulatory network. We calculate the probability distribution of the metastable state of the plasmids and show on this example that the reaction rate equations may fail in predicting the ...
arxiv +1 more source
Plasmids in Rhizobia: The Role of Nonsymbiotic Plasmids
Peer ...
Mercado-Blanco, Jesús, Toro, Nicolás
openaire +3 more sources
Plasmid persistence: costs, benefits, and the plasmid paradox [PDF]
Plasmids are extrachromosomal DNA elements that can be found throughout bacteria, as well as in other domains of life. Nonetheless, the evolutionary processes underlying the persistence of plasmids are incompletely understood. Bacterial plasmids may encode genes for traits that are sometimes beneficial to their hosts, such as antimicrobial resistance ...
Carroll, Amanda C., Wong, Alex
openaire +2 more sources
Predictive Modeling of Non-Viral Gene Transfer [PDF]
In non-viral gene delivery, the variance of transgenic expression stems from the low number of plasmids successfully transferred. Here, we experimentally determine Lipofectamine- and PEI-mediated exogenous gene expression distributions from single cell time-lapse analysis.
arxiv +1 more source
Conjugative Selectivity of Plasmids Is Affected by Coexisting Recipient Candidates
Understanding the mechanisms underlying plasmid behavior under conditions of various environments is important to predict the fate of plasmids in nature.
Ayako Sakuda+3 more
doaj +1 more source
Guidelines for the estimation and reporting of plasmid conjugation rates [PDF]
Conjugation is a central characteristic of plasmid biology and an important mechanism of horizontal gene transfer in bacteria. However, there is little consensus on how to accurately estimate and report plasmid conjugation rates, in part due to the wide range of available methods.
arxiv