Results 1 to 10 of about 459,674 (351)

Plasmodium telomere maintenance: uncovering the Achilles’ heel for novel antimalarials [PDF]

Frontiers in Cellular and Infection Microbiology
This review examines the potential of disrupting telomere maintenance in Plasmodium as a novel antimalarial strategy. Telomeres are repetitive DNA–protein structures located at chromosome termini, where they preserve genome stability and protect against ...
Theophilus N. Wakai, Theophilus N. Wakai, Dorathy O. Anzaku, Dorathy O. Anzaku, Israel S. Afolabi   +4 more
doaj   +2 more sources

Incidence of avian malaria in hummingbirds in humid premontane forests of Pichincha Province, Ecuador: A pilot study [PDF]

Veterinary World, 2021
Background and Aim: Avian malaria is a tropical disease caused by protozoans of the genera Plasmodium and Haemoproteus. As a nonlethal disease, avian malaria can affect the lifespan and reproductive rate of birds.
Claudia S. Abad, Markus P. Tellkamp, Isidro R. Amaro, Lilian M. Spencer   +3 more
doaj   +1 more source

Chromatin structure can introduce systematic biases in genome-wide analyses of Plasmodium falciparum [version 2; peer review: 2 approved]

Open Research Europe, 2022
Background: The maintenance, regulation, and dynamics of heterochromatin in the human malaria parasite, Plasmodium falciparum, has drawn increasing attention due to its regulatory role in mutually exclusive virulence gene expression and the silencing of ...
Jessica Bryant, Sebastian Baumgarten
doaj   +1 more source

Immunogenicity of a Plasmodium vivax vaccine based on the duffy binding protein formulated using adjuvants compatible for use in humans

Scientific Reports, 2023
The invasion of reticulocytes by Plasmodium vivax merozoites is dependent on the interaction of the Plasmodium vivax Duffy Binding Protein (PvDBP) with the Duffy antigen receptor for chemokines (DARC).
Francisco J. Martinez, Micheline Guillotte-Blisnick, Christèle Huon, Patrick England, Jean Popovici, Hélène Laude, Laurence Arowas, Marie-Noëlle Ungeheuer, Jenny M. Reimer, Darrick Carter, Steve Reed, Paushali Mukherjee, Virander S. Chauhan, Chetan E. Chitnis   +13 more
doaj   +1 more source

Malaria Active Case Finding is a Necessary Strategy in the Malaria Elimination Program: A Successful Experience in Iran [PDF]

Journal of Health Sciences and Surveillance System, 2023
Background: Case finding and malaria foci management is significant strategy for the prosperous performance of amalaria elimination program. Therefore, detection, treatment.
Maryam Sarani, Gholamali Javdan, Amin Ghanbarnejad, Ebrahim Eftekhar, Reza Safari, Khojasteh Sharifi- Sarasiabi, Shaghayegh Khojasteh, Habibollah Turki   +7 more
doaj   +1 more source

High prevalence of Plasmodium infection in fighting cocks in Thailand determined with a molecular method

Journal of Veterinary Research, 2022
Avian malaria caused by Plasmodium and the malaria-like parasites of the genus Haemoproteus has been regularly described in multiple regions worldwide. These parasites significantly affect many avian taxa, including domestic chickens and fighting cocks ...
Vaisusuk Kotchaphon, Chatan Wasupon, Seerintra Tossapol, Piratae Supawadee   +3 more
doaj   +1 more source

Double Jeopardy in Malaria Infected Children with Common Haemoglobinopathies: A Cross-sectional Study in Malaria Mesoendemic Districts of Ghana [PDF]

Journal of Clinical and Diagnostic Research, 2022
Introduction: Malaria and conditions associated with common haemoglobinopathies constitute a health threat to young children in sub-Saharan Africa. Malaria is known to exert some influence on common haemoglobin variants while haemoglobinopathies also ...
Raymond Charles Ehiem, Bernard Walter L Lawson, John Asiedu Larbi   +2 more
doaj   +1 more source

Imported Malaria in an Immigrant Toddler Boy in Kashan, a Non-Malaria Endemic Area, Central Iran

Journal of Medical Microbiology and Infectious Diseases, 2022
Malaria is an imported disease in non-endemic regions of Iran. Imported malaria cases to Iran mostly come from illegal immigrants from neighboring eastern countries.
Tayebeh Taghipour1, Mahzad Erami2, Mojtaba Fakhrei2, Hossein Hooshyar1*   +3 more
doaj   +1 more source

Disease progression in Plasmodium knowlesi malaria is linked to variation in invasion gene family members. [PDF]

, 2014
Emerging pathogens undermine initiatives to control the global health impact of infectious diseases. Zoonotic malaria is no exception. Plasmodium knowlesi, a malaria parasite of Southeast Asian macaques, has entered the human population. P.
A Berry, AA Semenya, AK Bei, Angela Siner, Atique M. Ahmed, B Singh, B Singh, Balbir Singh, BE Barber, BE Barber, C Aurrecoechea, C Daneshvar, Chan Woon Lu, CV Jennings, EV Meyer, G Butcher, G Snounou, H Ozwara, Ing Tien Wong, J Cox-Singh, J Cox-Singh, J Cox-Singh, J Cox-Singh, J Langhorne, J Li, J Rayner, Janet Cox-Singh, JC Barrett, JC Rayner, JC Rayner, JP Cramer, JW Barnwell, K Gunalan, K Hayton, Kenji Hirayama, KS Lee, L Excoffier, LH Bannister, LH Miller, LH Miller, M Willmann, MAM Sallum, Matthias Willmann, Miguel M. Pinheiro, MR Galinski, MR Galinski, N Gomez-Escobar, P Librado, Paul C. Divis, Ramlah Zainudin, RW Moon, S Kumar, S Lopaticki, S Nakazawa, Sanjeev Krishna, Sarina K. Singh-Khaira, Scott B. Millar, Sean Lynch, SL Takala, T William, TM DeSimone, WH Tham   +61 more
core   +11 more sources

The NTP generating activity of pyruvate kinase II is critical for apicoplast maintenance in Plasmodium falciparum

eLife, 2020
The apicoplast of Plasmodium falciparum parasites is believed to rely on the import of three-carbon phosphate compounds for use in organelle anabolic pathways, in addition to the generation of energy and reducing power within the organelle.
Russell P Swift, Krithika Rajaram, Cyrianne Keutcha, Hans B Liu, Bobby Kwan, Amanda Dziedzic, Anne E Jedlicka, Sean T Prigge   +7 more
doaj   +1 more source