Results 1 to 10 of about 310,877 (350)

Double Jeopardy in Malaria Infected Children with Common Haemoglobinopathies: A Cross-sectional Study in Malaria Mesoendemic Districts of Ghana [PDF]

Journal of Clinical and Diagnostic Research, 2022
Introduction: Malaria and conditions associated with common haemoglobinopathies constitute a health threat to young children in sub-Saharan Africa. Malaria is known to exert some influence on common haemoglobin variants while haemoglobinopathies also ...
Raymond Charles Ehiem, Bernard Walter L Lawson, John Asiedu Larbi   +2 more
doaj   +1 more source

Imported Malaria in an Immigrant Toddler Boy in Kashan, a Non-Malaria Endemic Area, Central Iran

Journal of Medical Microbiology and Infectious Diseases, 2022
Malaria is an imported disease in non-endemic regions of Iran. Imported malaria cases to Iran mostly come from illegal immigrants from neighboring eastern countries.
Tayebeh Taghipour1, Mahzad Erami2, Mojtaba Fakhrei2, Hossein Hooshyar1*   +3 more
doaj   +1 more source

Molecular Mechanisms of Drug Resistance in Plasmodium falciparum Malaria.

Annual Review of Microbiology, 2020
Understanding and controlling the spread of antimalarial resistance, particularly to artemisinin and its partner drugs, is a top priority. Plasmodium falciparum parasites resistant to chloroquine, amodiaquine, or piperaquine harbor mutations in the P ...
Kathryn J. Wicht, Sachel Mok, D. Fidock
semanticscholar   +1 more source

The NTP generating activity of pyruvate kinase II is critical for apicoplast maintenance in Plasmodium falciparum

eLife, 2020
The apicoplast of Plasmodium falciparum parasites is believed to rely on the import of three-carbon phosphate compounds for use in organelle anabolic pathways, in addition to the generation of energy and reducing power within the organelle.
Russell P Swift, Krithika Rajaram, Cyrianne Keutcha, Hans B Liu, Bobby Kwan, Amanda Dziedzic, Anne E Jedlicka, Sean T Prigge   +7 more
doaj   +1 more source

Song sparrows Melospiza melodia have a home-field advantage in defending against sympatric malarial parasites [PDF]

Royal Society Open Science, 2016
Hosts and parasites interact on both evolutionary and ecological timescales. The outcome of these interactions, specifically whether hosts are more resistant to their local parasites (sympatric) than to parasites from another location (allopatric), is ...
Yanina Sarquis-Adamson, Elizabeth A. MacDougall-Shackleton   +1 more
doaj   +1 more source

Ultrasensitive CRISPR-based diagnostic for field-applicable detection of Plasmodium species in symptomatic and asymptomatic malaria

Proceedings of the National Academy of Sciences of the United States of America, 2020
Significance Detection of submicroscopic malaria in asymptomatic individuals is needed for eradication and remains a diagnostic gap in resource-limited settings. Nonfalciparum clinical diagnostics are a second gap, as these infections have a low parasite
Rose A. Lee, Helena de Puig, P. Nguyen, Nicolaas M. Angenent-Mari, Nina M. Donghia, James P. McGee, Jeffrey D. Dvorin, C. Klapperich, N. Pollock, J. Collins   +9 more
semanticscholar   +1 more source

Genomic epidemiology of artemisinin resistant malaria

eLife, 2016
The current epidemic of artemisinin resistant Plasmodium falciparum in Southeast Asia is the result of a soft selective sweep involving at least 20 independent kelch13 mutations.
MalariaGEN Plasmodium falciparum Community Project
doaj   +1 more source

Possible evidence of gluconeogenesis in Plasmodium- Infected children in relationship with the parasite density

Biomedical and Biotechnology Research Journal, 2020
Background: Gluconeogenesis is stimulated by low blood glucose to maintain the glucose level; it involves lipolysis (breaking down of triglycerides), release of cortisol, and production of glycerol which can be converted into glucose.
Mathew Folaranmi Olaniyan, Tolulope Busayo Ojediran, Shedarck Gbenga Olayinka   +2 more
doaj   +1 more source

The effect of malaria control on Plasmodium falciparum in Africa between 2000 and 2015

Nature, 2015
Since the year 2000, a concerted campaign against malaria has led to unprecedented levels of intervention coverage across sub-Saharan Africa. Understanding the effect of this control effort is vital to inform future control planning.
S. Bhatt, D. Weiss, E. Cameron, D. Bisanzio, B. Mappin, U. Dalrymple, K. Battle, C. Moyes, Andrew J. Henry, P. Eckhoff, E. Wenger, O. Briët, O. Briët, M. Penny, M. Penny, T. Smith, T. Smith, A. Bennett, J. Yukich, T. Eisele, J. Griffin, C. Fergus, Michael Lynch, F. Lindgren, Justin M. Cohen, C. Murray, Dave L. Smith, Simon Iain Hay, Simon Iain Hay, Simon Iain Hay, R. Cibulskis, P. Gething   +31 more
semanticscholar   +1 more source

Gut Microbiota Composition Modulates the Magnitude and Quality of Germinal Centers during Plasmodium Infections

Cell Reports, 2020
Summary: Gut microbiota composition is associated with human and rodent Plasmodium infections, yet the mechanism by which gut microbiota affects the severity of malaria remains unknown.
Morgan L. Waide, Rafael Polidoro, Whitney L. Powell, Joshua E. Denny, Justin Kos, David A. Tieri, Corey T. Watson, Nathan W. Schmidt   +7 more
doaj   +1 more source