Results 111 to 120 of about 310,877 (350)

Changes in genome organization of parasite-specific gene families during the Plasmodium transmission stages

Nature Communications, 2018
The development of malaria parasites throughout their various life cycle stages is coordinated by changes in gene expression. We previously showed that the three-dimensional organization of the Plasmodium falciparum genome is strongly associated with ...
E. Bunnik, Kate B. Cook, Nelle Varoquaux, G. Batugedara, J. Prudhomme, Anthony Cort, Lirong Shi, C. Andolina, Leila S Ross, D. Brady, D. Fidock, F. Nosten, R. Tewari, P. Sinnis, F. Ay, Jean-Philippe Vert, William Stafford Noble, K. L. Le Roch   +17 more
semanticscholar   +1 more source

A Set of Rapid Diagnostic Tool for Babesia microti Infection

Journal of Clinical Laboratory Analysis, EarlyView.
This study develops a cross‐priming amplification combined with vertical flow visualization (CPA‐VF) assay for rapid, low‐cost detection of Babesia microti, achieving a detection limit of 2.56 fg/reaction (equivalent to 0.000004% parasitic red blood cells) with 95.5% sensitivity and specificity compared to nested PCR.
Yanan Bai, Shangdi Zhang, Qindong Liang, Xinxin Zhang, Zeen Liu, Yuxin Ye, Jianxun Luo, Hong Yin, Chongge You, Guiquan Guan, Jinming Wang   +10 more
wiley   +1 more source

Calpain Proteases and the Evolving Signaling Network in Insect Embryonic Patterning

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
Insect embryonic Dorsal‐Ventral (DV) patterning relies on the BMP and Toll pathways to different extents. Calcium‐dependent cystein proteases of the Calpain family also exert an important function to pattern the DV axis. In Drosophila, Calpain A cleaves the Cactus/IkappaB inhibitor and modifies Toll signals in ventral regions of the embryo. In Rhodnius
Alison Julio, Helena Araujo
wiley   +1 more source

Editorial: Identification and Characterization of Novel Antigens of Malarial Parasites

Frontiers in Cellular and Infection Microbiology, 2022
Md Atique Ahmed, Feng Lu, Yang Cheng, Jin-Hee Han   +3 more
doaj   +1 more source

Liver function tests among children with moderate acute malnutrition: A secondary analysis of a randomized trial from Burkina Faso

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Hepatic steatosis has been described in children with severe acute malnutrition, but the degree of liver damage in children with moderate acute malnutrition (MAM) is unknown. This study aimed to investigate the development of malnutrition‐associated liver damage by describing liver function tests among children with MAM.
Christina L. Winther, Thora W. Helt, Christian Fabiansen, Ruth Frikke‐Schmidt, Suzanne Filteau, André Briend, Kim F. Michaelsen, Henrik Friis, Vibeke B. Christensen   +8 more
wiley   +1 more source

Plant defense strategies: The dual armor of disease resistance and tolerance

New Plant Protection, EarlyView.
Plants employ dual strategies against pathogens: Resistance limits invasion via immune responses, whereas tolerance mitigates damage to sustain growth—together enhancing survival under infections. Abstract Pathogen infections pose a significant threat to plant health, global food security, and ecosystems.
Zhijuan Tang, Shaosong Shi, Xinyu Du, Guoyong Xu   +3 more
wiley   +1 more source

Plasmodium malariae and P. ovale genomes provide insights into malaria parasite evolution

Nature, 2017
Elucidation of the evolutionary history and interrelatedness of Plasmodium species that infect humans has been hampered by a lack of genetic information for three human-infective species: P. malariae and two P. ovale species (P. o. curtisi and P.
Gavin G. Rutledge, U. Böhme, M. Sanders, A. Reid, J. Cotton, Oumou Maiga-Ascofare, A. Djimde, T. Apinjoh, L. Amenga-Etego, M. Manske, J. Barnwell, F. Renaud, B. Ollomo, F. Prugnolle, N. Anstey, Sarah Auburn, R. Price, J. McCarthy, D. Kwiatkowski, C. Newbold, M. Berriman, T. Otto   +21 more
semanticscholar   +1 more source

A Possible Case of β‐Thalassemia From the Cemetery of Santa Maria Maggiore in Vercelli (Piedmont, Northern Italy,18th Century)

International Journal of Osteoarchaeology, EarlyView.
ABSTRACT In Italy's Piedmont region, the city of Vercelli has a history of malaria transmission due to favorable conditions for Anopheles mosquitoes, which may have influenced the genetic prevalence of thalassemia. This study investigates the skeletal remains of a nonadult individual from the Church of Santa Maria Maggiore in Vercelli, dating to the ...
R. Fusco, C. Tesi, A. Mazzucchi, A. Vanni, M. Licata   +4 more
wiley   +1 more source

THE TECHNIQUE OF TESTING CHEMOTHERAPEUTIC ACTION ON PLASMODIUM GALLINACEUM [PDF]

, 1947
Isabel M. Tonkin, Frank Hawking
openalex   +1 more source

Platelets kill circulating parasites of all major Plasmodium species in human malaria.

Blood, 2018
Platelets are understood to assist host innate immune responses against infection, although direct evidence of this function in any human disease, including malaria, is unknown.
Steven Kho, Bridget E. Barber, Edison Johar, B. Andries, J. Poespoprodjo, E. Kenangalem, Kim A. Piera, Anna Ehmann, R. Price, T. William, T. Woodberry, S. Foote, Gabriela Minigo, T. Yeo, M. Grigg, N. Anstey, B. McMorran   +16 more
semanticscholar   +1 more source