Results 111 to 120 of about 317,079 (354)
The FEBS Journal, EarlyView.The Leishmania phosphatase PTP1, and possibly the genetically similar PTP2, interacts with the Leishmania transmembrane protein DUF21. When both ptp1 and ptp2 are knocked out of Leishmania (LdΔPTP1/2), the parasite can no longer survive without magnesium in vitro and has reduced viability in the host macrophage. Conversely, in duf21 knockout (LdΔDUF21),
Kayla Paulini +6 more
wiley +1 more source
Nature Communications, 2018 The development of malaria parasites throughout their various life cycle stages is coordinated by changes in gene expression. We previously showed that the three-dimensional organization of the Plasmodium falciparum genome is strongly associated with ...
E. Bunnik +17 more
semanticscholar +1 more source
The structural, functional, and therapeutic potential of metacaspases in fungi and protozoa
The FEBS Journal, EarlyView.Metacaspases are Ca2+‐dependent cysteine proteases whose structural characteristics, particularly calcium binding and autocatalytic processing, govern their activation and biological functions. These enzymes differ among microorganisms and regulate their cell cycles, making them excellent targets for drug development.
Ane C. M. Duarte +9 more
wiley +1 more source
Indigenous Plasmodium ovale Malaria in Bangladesh [PDF]
, 2010 Hans‐Peter Fuehrer +11 more
openalex +1 more source
Malaria Research and Treatment, 2019 Background Malaria is a protozoan disease caused by the Plasmodium species. Among the five Plasmodium species. Among the five Plasmodium falciparum and Plasmodium vivax malaria are by far the most predominant and widely distributed in Ethiopia.
Teshiwal Deress, M. Girma
semanticscholar +1 more source
Molecular Testing in Sickle Cell Disease: From Newborn Screening to Transfusion Care
International Journal of Laboratory Hematology, EarlyView.ABSTRACT Sickle cell disease (SCD) is one of the most frequent monogenic diseases worldwide and a highly heterogeneous and complex disease. SCD care carries several challenges. This includes early and accurate diagnosis as well as optimal red blood cell transfusion matching in this population carrying a high risk of alloimmunization.
Thomas Pincez, Yves D. Pastore
wiley +1 more source
The Rough Guide to Monocytes in Malaria Infection
Frontiers in Immunology, 2018 While half of the world's population is at risk of malaria, the most vulnerable are still children under five, pregnant women and returning travelers. Anopheles mosquitoes transmit malaria parasites to the human host; but how Plasmodium interact with the
Amaya Ortega-Pajares +1 more
doaj +1 more source
High Rate of Treatment Failures in Nonimmune Travelers Treated With Artemether-Lumefantrine for UncomplicatedPlasmodium falciparumMalaria in Sweden: Retrospective Comparative Analysis of Effectiveness and Case Series [PDF]
, 2016 Klara Sondén +9 more
openalex +1 more source
Platelets kill circulating parasites of all major Plasmodium species in human malaria.
Blood, 2018 Platelets are understood to assist host innate immune responses against infection, although direct evidence of this function in any human disease, including malaria, is unknown.
Steven Kho +16 more
semanticscholar +1 more source