Results 111 to 120 of about 176,373 (221)

Improving Malaria Parasite Gene Flow Inference Under Sparse Spatial Sampling

Molecular Ecology Resources, Volume 26, Issue 6, August 2026.
ABSTRACT Estimating malaria parasite migration is crucial for informing elimination strategies, particularly by identifying regions with higher parasite migration that may serve as transmission sources and intervention targets. Methods that infer spatial variations in gene flow from georeferenced genetic data, including Estimated Effective Migration ...
Yao Li, Bing Guo, Timothy D. O'Connor, Shannon Takala‐Harrison, Kathleen Stewart   +4 more
wiley   +1 more source

Vectors and Vector‐Borne Diseases: Biology, Epidemiology and Integrated Control Strategies

Journal of Applied Entomology, Volume 150, Issue 7, Page 990-1015, August 2026.
ABSTRACT Vector‐Borne Diseases (VBDs), transmitted by arthropods such as mosquitoes, ticks, fleas and sandflies, represent a significant threat to global health. These diseases can be caused by a variety of pathogens, including bacteria, viruses, protozoa, and helminths.
Roberta Rinaldi, Carmen Scieuzo, Federica De Stefano, Luca Masucci, Patrizia Falabella   +4 more
wiley   +1 more source

Hematology and Serum Biochemistry Reference Intervals for Captive‐Born Owl Monkeys (Aotus nancymae): Effects of Age and Sex

Journal of Medical Primatology, Volume 55, Issue 4, August 2026.
ABSTRACT Background Owl monkeys (Aotus spp.) are a nocturnal nonhuman primate (NHP) native to central and South America that are used as infectious disease research models for human diseases, such as malaria and human immunodeficiency virus. Natural and infectious diseases may cause alterations in the hematology and serum biochemistry values, which ...
Sarah M. Kezar, Sarah J. Neal, Gregory K. Wilkerson   +2 more
wiley   +1 more source

Short‐Course Low‐Dose Primaquine for Radical Cure in G6PD‐Normal Patients in the Pre‐Elimination Context of Nepal

Tropical Medicine &International Health, Volume 31, Issue 8, Page 1028-1034, August 2026.
ABSTRACT Background Plasmodium vivax remains a challenge for malaria elimination in Nepal due to its ability to relapse. Radical cure with primaquine is effective but limited by poor adherence to the standard 14‐day low‐dose regimen. In 2022, the WHO recommended administering the same total dose (3.5 mg/kg) over 7 days to improve adherence.
Prakash Ghimire, Gokarna Dahal, Nabaraj Adhikari, Komal Raj Rijal, Sanjib Adhikari, Megha Raj Banjara, Hellen Mnjala, Grant Lee, Sophie Weston, Angela Rumaseb, Anjana Rai, Benedikt Ley, Mohammad Sharif Hossain, Julie A. Simpson, Megha Rajasekhar, Bipin Adhikari, Ric N. Price, Bibek K. Lal, Kamala Thriemer   +18 more
wiley   +1 more source

Life Course Malaria Exposure and SARS‐CoV‐2 Seroepidemiology in Ugandan Adolescents: A Longitudinal Study Nested in a Birth Cohort

Tropical Medicine &International Health, Volume 31, Issue 8, Page 1012-1027, August 2026.
ABSTRACT Background COVID‐19 has had major global health impacts, yet reported morbidity and mortality have been lower in Africa despite serological evidence of widespread infection. Malaria has been proposed as a potential modifier of susceptibility to and outcomes of SARS‐CoV‐2 infection.
Ludoviko Zirimenya, Doreen Nayebare, Claire Baine, Jacent Nassuuna, Milly Namutebi, Christopher Zziwa, Denis Nsubuga, Fred Kiwudhu, Florence Akello, Josephine Tumusiime, Gloria Oduru, Grace Kabami, Hellen Akurut, Rachel Nakyesige, Agnes Natukunda, Anne Wajja, Lawrence Lubyayi, Simon Kimuda, Gyaviira Nkurunungi, Jennifer Serwanga, Katie J. Doores, Emily L. Webb, Alison M. Elliott   +22 more
wiley   +1 more source

Editorial: Advancement in malaria treatment

Frontiers in Cellular and Infection Microbiology
Sarika Gunjan, Manish Goyal
doaj   +1 more source

Hybrid Aminoferrocenes With Nitrate Esters for In Situ Peroxynitrite Generation: Complex Interplay Between Redox Chemistry, NO‐Donor Reactivity, and Aminoferrocene Activation Influences In Vitro Anticancer Activity

ChemBioChem, Volume 27, Issue 13, 14 July 2026.
Aminoferrocene‐based prodrugs represent a promising class of redox‐active anticancer agents that can be selectively activated in oxidative cellular environments. However, activation of these systems typically relies on reactive oxygen species (ROS) and is therefore inefficient in intracellular compartments with low ROS levels, such as the cytoplasm. In
Hülya Gizem Özkan, Roman Selin, Paula Holst, Rainer Tietze, Christoph Alexiou, Andriy Mokhir   +5 more
wiley   +1 more source

Metal–Drug Complexes as Long‐Release Application for Antimalarial PfFNT‐Inhibitors

ChemMedChem, Volume 21, Issue 13, 14 July 2026.
P. falciparum formate‐nitrite transporter (PfFNT) inhibitors have emerged as a novel antimalarial class with potent in vivo and liver‐stage activity. Low‐solubility metal–inhibitor complexes were prepared as potential long‐acting injectables.
Finn Tiedjens, Björn Henke, Ulrich Girreser, Regina Scherließ, Eric Beitz   +4 more
wiley   +1 more source

Hit‐To‐Lead Optimization of a Pyridylpiperazine Class Against Malaria: Pharmacokinetic Profile and In Vivo Efficacy of Optimized Compounds

ChemMedChem, Volume 21, Issue 13, 14 July 2026.
Chemical optimization of a novel pyridylpiperazine class yields two promising antimalarial candidates with an exceptional balance of metabolic stability and solubility. These optimized leads significantly protect mice from cerebral malaria, reducing parasitic load by up to 91.7%.
Douglas Davison da Silva Oliveira, Duarte Eduardo Pereira, Rafael Consolin Chelucci, Simone Michelan, Júlia Maria Fernandes Pituba, Adriano D. Andricopulo, Leonardo L. G. Ferreira, Neide Maria Silva, Celso de Oliveira Rezende Júnior   +8 more
wiley   +1 more source

Hidden hematological, biochemical and immune costs of asymptomatic malaria infections in semi-wild chimpanzees. [PDF]

PLoS Pathog
Nowakowski A, Elguero E, Patterson K, Boissière A, Degrugillier F, Sidobre C, Arnathau C, Grentzinger P, Willaume E, Talman AM, Malleret B, Boundenga L, Ngoubangoye B, Prugnolle F, Wassmer SC, Rougeron V.   +15 more
europepmc   +1 more source