Results 151 to 160 of about 384,388 (342)

Editorial: Identification and Characterization of Novel Antigens of Malarial Parasites

Frontiers in Cellular and Infection Microbiology, 2022
Md Atique Ahmed, Feng Lu, Yang Cheng, Jin-Hee Han   +3 more
doaj   +1 more source

THE TECHNIQUE OF TESTING CHEMOTHERAPEUTIC ACTION ON PLASMODIUM GALLINACEUM [PDF]

, 1947
Isabel M. Tonkin, Frank Hawking
openalex   +1 more source

UCT943, a Next-Generation Plasmodium falciparum PI4K Inhibitor Preclinical Candidate for the Treatment of Malaria

Antimicrobial Agents and Chemotherapy, 2018
The 2-aminopyridine MMV048 was the first drug candidate inhibiting Plasmodium phosphatidylinositol 4-kinase (PI4K), a novel drug target for malaria, to enter clinical development.
Christel Brunschwig, N. Lawrence, Dale Taylor, E. Abay, Mathew Njoroge, G. Basarab, C. Le Manach, Tanya Paquet, Diego González Cabrera, Aloysius T. Nchinda, C. de Kock, L. Wiesner, P. Denti, D. Waterson, Benjamin Blasco, D. Leroy, M. Witty, C. Donini, James Duffy, S. Wittlin, K. White, S. Charman, M. Jiménez-Díaz, Iñigo Angulo-Barturen, E. Herreros, F. Gamo, R. Rochford, D. Mancama, T. Coetzer, Mariëtte E. van der Watt, J. Reader, L. Birkholtz, K. Marsh, S. Solapure, J. Burke, J. A. McPhail, M. Vanaerschot, D. Fidock, P. Fish, P. Siegl, Dennis A. Smith, Grennady Wirjanata, Rintis Noviyanti, R. Price, J. Marfurt, K. Silué, L. Street, K. Chibale   +47 more
semanticscholar   +1 more source

Enrichment of Helminth Mitochondrial Genomes From Faecal Samples Using Hybridisation Capture

Molecular Ecology Resources, EarlyView.
ABSTRACT New approaches are urgently needed to enrich rare or low‐abundant DNA in complex samples. Soil‐transmitted helminths (STHs) inhabit heterogeneous environments, including the gastrointestinal tract of their host as adults and are excreted as eggs and larvae in faeces, complicating our understanding of their biology and the use of genetic tools ...
Marina Papaiakovou, Andrea Waeschenbach, Roy M. Anderson, Piet Cools, Zeleke Mekonnen, D. Timothy J. Littlewood, Cinzia Cantacessi, Stephen R. Doyle   +7 more
wiley   +1 more source

Internationally Adopted and Migrant Children Had Important Health Issues Requiring Systematic Initial Screening at Arrival

Acta Paediatrica, EarlyView.
ABSTRACT Aim Internationally adopted and migrant children have similar profiles as they may have experienced many adversities before arrival in their new country. We sought to compare both groups at arrival, focusing on nutritional status, infections and vaccination status.
Céline Lafay, Laurie Miller, Juliette Goutines, Enora Leroux, Albert Faye, Frédéric Sorge   +5 more
wiley   +1 more source

Blood Stage Malaria Disrupts Humoral Immunity to the Pre-erythrocytic Stage Circumsporozoite Protein

Cell Reports, 2016
Many current malaria vaccines target the pre-erythrocytic stage of infection in the liver. However, in malaria-endemic regions, increased blood stage exposure is associated with decreased vaccine efficacy, thereby challenging current vaccine efforts.
Gladys J. Keitany, Karen S. Kim, Akshay T. Krishnamurty, Brian D. Hondowicz, William O. Hahn, Nicholas Dambrauskas, D. Noah Sather, Ashley M. Vaughan, Stefan H.I. Kappe, Marion Pepper   +9 more
doaj   +1 more source

Structure and function based design of Plasmodium-selective proteasome inhibitors

Nature, 2016
The proteasome is a multi-component protease complex responsible for regulating key processes such as the cell cycle and antigen presentation. Compounds that target the proteasome are potentially valuable tools for the treatment of pathogens that depend ...
Hao Li, A. O’Donoghue, Wouter A. van der Linden, S. Xie, Euna Yoo, Ian T. Foe, L. Tilley, C. Craik, P. D. da Fonseca, M. Bogyo   +9 more
semanticscholar   +1 more source

Reimagining Social Value to Consider the Environment: How Should We Judge the Magnitude of Benefits in Health Research?

Bioethics, EarlyView.
ABSTRACT Growing recognition of intersections between our health and the environment, healthcare systems and the environment, and health research and the environment has led bioethics scholars to advocate that the field readopt a broader perspective that considers nature.
Bridget Pratt, Rieke van der Graaf
wiley   +1 more source

The Promise of Systems Biology Approaches for Revealing Host Pathogen Interactions in Malaria

Frontiers in Microbiology, 2017
Despite global eradication efforts over the past century, malaria remains a devastating public health burden, causing almost half a million deaths annually (WHO, 2016).
Meghan Zuck, Laura S. Austin, Samuel A. Danziger, Samuel A. Danziger, John D. Aitchison, John D. Aitchison, Alexis Kaushansky, Alexis Kaushansky   +7 more
doaj   +1 more source

Notes on the Plasmodium of Badhamia utricularis and Brefeldia maxima [PDF]

, 1888
AM Lister
openalex   +1 more source