Results 81 to 90 of about 258,281 (284)

Physiological, environmental, and life-history drivers of haemosporidian infections in non-passerine birds from a rehabilitation center

Frontiers in Parasitology
IntroductionPathogens and parasites play a crucial role in shaping ecological and evolutionary processes, influencing the behavior, physiology, and survival of their hosts across diverse ecosystems.
Lis Marques de Carvalho e Vieira, Victor Aguiar de Souza Penha, Kevin J. McGraw, Amanda Vitória Dornelas da Silva, Erika Martins Braga   +4 more
doaj   +1 more source

The αTSR Domain of Plasmodium Circumsporozoite Protein Bound Heparan Sulfates and Elicited High Titers of Sporozoite Binding Antibody After Displayed by Nanoparticles

International Journal of Nanomedicine, 2023
Ming Xia,1 Frank Vago,2 Ling Han,3 Pengwei Huang,1 Linh Nguyen,3 Geert-Jan Boons,4– 6 John S Klassen,3 Wen Jiang,2 Ming Tan1,7 1Division of Infectious Diseases, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA; 2Department of Biological
Xia M, Vago F, Han L, Huang P, Nguyen L, Boons GJ, Klassen JS, Jiang W, Tan M   +8 more
doaj  

A small mitochondrial protein present in myzozoans is essential for malaria transmission [PDF]

Open Biology, 2016
Myzozoans (which include dinoflagellates, chromerids and apicomplexans) display notable divergence from their ciliate sister group, including a reduced mitochondrial genome and divergent metabolic processes.
Dennis Klug, Gunnar R. Mair, Friedrich Frischknecht, Ross G. Douglas   +3 more
doaj   +1 more source

The dynamics of natural Plasmodium falciparum infections. [PDF]

, 2012
BACKGROUND: Natural immunity to Plasmodium falciparum has been widely studied, but its effects on parasite dynamics are poorly understood. Acquisition and clearance rates of untreated infections are key elements of the dynamics of malaria, but estimating
Ingrid Felger (92160), Beck, Hans-Peter, Sama, W., Beck, H. P., Tiaden, A., Hans-Peter Beck, Bretscher, M., Nicole Falk (134915), Owusu-Agyei, Seth, Beck Hans-Peter, Felger Ingrid, Felger, Ingrid, Sama, Wilson, Sama Wilson, Maire, Martin, Tiaden, André, Ingrid Felger, Falk, Nicole, Wilson Sama (134920), Thomas A. Smith (95630), Wilson Sama, Bretscher, Michael T, André Tiaden, Seth Owusu-Agyei (80063), Tiaden André, Bretscher Michael T., Owusu-Agyei, S., Felger, I., Seth Owusu-Agyei, Owusu-Agyei Seth, Smith, T. A., Hans-Peter Beck (129757), Maire Martin, Martin Maire (134910), André Tiaden (134918), Michael T Bretscher, Michael T. Bretscher (134912), Falk Nicole, Martin Maire, Smith, Thomas A, Thomas A Smith, Falk, N., Maire, N., Nicole Falk, Smith Thomas A.   +44 more
core   +1 more source

Opsoclonus in Pediatric Patients: Differential Diagnosis and a Practical Approach to Evaluation

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Opsoclonus is an ocular dyskinesia characterized by involuntary, arrhythmic, multidirectional saccades. In pediatrics, opsoclonus is most commonly attributed to the rare neuroinflammatory disorder opsoclonus‐myoclonus‐ataxia syndrome (OMAS), typically considered a paraneoplastic syndrome associated with neural crest tumors. However, opsoclonus
Aubrey C. Reed, Supreet S. Randhawa, Jason H. Peragallo, Prabhumallikarjun Patil, Grace Gombolay, Varun Kannan   +5 more
wiley   +1 more source

Antimalarial potential of Kerala Ayurvedic Water “Pathimugam”

Journal of Vector Borne Diseases
Background & objectives: The persistent threat of drug resistant malaria demands new cures. Low prevalence of malaria in the Indian state of Kerala compared with other proximal states led us to explore if there is any traditional practice in Kerala which
Naveen Kumar Kaushik, Dinkar Sahal
doaj   +1 more source

Blood-stage parasitaemia and age determine Plasmodium falciparum and P. vivax gametocytaemia in Papua New Guinea [PDF]

, 2015
A better understanding of human-to-mosquito transmission is crucial to control malaria. In order to assess factors associated with gametocyte carriage, 2083 samples were collected in a cross-sectional survey in Papua New Guinea.
Ingrid Felger (92160), Robinson, LJ, Mary Salib, Koepfli, Cristian, Peter Siba (112258), Koepfli, C, Cristian Koepfli, Nuitragool, W, Felger, Ingrid, Nuitragool, Wang, Ingrid Felger, Barry, AE, Ivo Mueller (46609), Salib, Mary, Naomi Sambale, Barry, Alyssa E., Felger, I, Leanne J. Robinson (137914), Patricia Rarau (137896), Salib, M, Rarau, Patricia, Patricia Rarau, Sambale, Naomi, Wampfler, R, Mueller, Ivo, Wang Nuitragool (742827), Sambale, N, Siba, P, Alyssa E Barry, Ivo Mueller, Peter Siba, Rahel Wampfler (464173), Alyssa E. Barry (136829), Siba, Peter, Mary Salib (175162), Naomi Sambale (680186), Betuela, Inoni, Mueller, I, Inoni Betuela, Wampfler, Rahel, Leanne J Robinson, Rarau, P, Betuela, I, Inoni Betuela (67110), Robinson, Leanne J., Rahel Wampfler, Cristian Koepfli (191306), Wang Nuitragool   +47 more
core   +2 more sources

Repurposing Drugs for Malaria through a Human Dose Prediction: A Case Study with Berzosertib

Clinical Pharmacology &Therapeutics, EarlyView.
Repurposing drugs whose clinical safety has been established offers a valuable approach to reduce the cost and time associated with the development of new drugs for malaria. Here, we investigate the potential to repurpose the anticancer kinase inhibitor berzosertib for the treatment of malaria, by assessing whether a predicted efficacious human dose ...
Devasha Redhi, Mwila Mulubwa, Mmakwena M. Mmonwa, Mathew Njoroge, Liezl Krugmann, Kelly Chibale   +5 more
wiley   +1 more source

Genetic diversity of Plasmodium falciparum among school-aged children from the Man region, western Côte d'Ivoire [PDF]

, 2013
The genetic diversity of Plasmodium falciparum allows the molecular discrimination of otherwise microscopically identical parasites and the identification of individual clones in multiple infections. The study reported here investigated the P. falciparum
Silué, Kigbafori D., Giovanna Raso, Raso, Giovanna, Utzinger, Jürg, N. Guetta, Simon P., Mara, Sarah E., Marcel Tanner, Simon P N’Guetta, Sarah E Mara, Kigbafori D Silué, Ding, Xavier C., Eliézer K N’Goran, Xavier C Ding, Jürg Utzinger, N. Goran, Eliézer K., Tanner, Marcel   +15 more
core   +1 more source

Long‐Acting Therapeutics in Pediatric Health: Bridging Innovation and Access

Clinical Pharmacology &Therapeutics, EarlyView.
Children have distinct therapeutic needs arising from age‐dependent physiology, disease epidemiology, formulation requirements, dosing considerations, and safety vulnerabilities. Despite substantial reductions in childhood mortality over the past three decades, nearly 5 million children under five died in 2023, with infectious diseases continuing to ...
Prajith Venkatasubramanian, Moherndran Archary, Daniel B. Hawcutt, Rachel Daley, Edmund Capparelli, Adeniyi Olagunju   +5 more
wiley   +1 more source