Results 141 to 150 of about 296,027 (331)

Mammalian TatD DNase domain containing 1 (TATDN1) is a proteostasis‐responsive gene with roles in ventricular structure and neuromuscular function

The FEBS Journal, EarlyView.
Twin‐arginine translocation D (TatD) homologs are found across all kingdoms, with debated roles in DNA degradation and protein quality control in unicellular organisms. We characterize TATDN1, the mammalian TatD orthologue, as a proteostatic stress‐responsive cytosolic protein dispensable for DNA degradation.
Gisel Barés, Aida Beà, Anna Sancho‐Balsells, Juan G Valero, David Aluja, Javier Inserte, Sandra García‐Carpi, Elisabet Miró‐Casas, Sara Borràs‐Pernas, Sara Hernández, Ana Martínez‐Val, Jesper V Olsen, Francesc Tebar, Xavier Cañas, Joan X. Comella, Patricia Pérez‐Galán, Marisol Ruiz‐Meana, Albert Giralt, Marta Llovera, Daniel Sanchis   +19 more
wiley   +1 more source

Identification of Plasmodium falciparum var1CSA and var2CSA domains that bind IgM natural antibodies [PDF]

, 2006
Malaria in pregnancy is responsible for maternal anaemia, low-birth-weight babies and infant deaths. Plasmodium falciparum infected erythrocytes are thought to cause placental pathology by adhering to host receptors such as chondroitin sulphate A (CSA ...
Ahmed Raza, Atalay, Baruch, Baruch, Buffet, Chen, Chen, Chitnis, Cohen, Cooke, Craig, Creasey, Fagan, Flick, Fried, Gamain, Gamain, Gardner, Guyatt, J. Alexandra Rowe, Jean-Philippe Semblat, Kyes, Kyes, Langone, Lin, Mayor, Medina, Medina, Rowe, Rowe, Rowe, Salanti, Salanti, Scholander, Smith, Smith, Su, Sue A. Kyes   +37 more
core   +1 more source

Investigation on possible transmission of monkeys' Plasmodium to human in a populations living in the equatorial rainforest of the Democratic republic of Congo

International Journal for Parasitology: Parasites and Wildlife, 2016
Plasmodiums are protozoa that may infect various hosts. Only five species are now recognized as naturally parasitizing humans: Plasmodium falciparum, Plasmodium vivax, Plasmodium malariae, Plasmodium ovale and Plasmodium knowlesi.
Dieudonné Makaba Mvumbi, Thierry Lengu Bobanga, Solange Efundu Umesumbu, Billy Shako Kunyu, Jean-Marie Ntumba Kayembe, Nani-Tuma H. Situakibanza, Georges Lelo Mvumbi, Pierrette Melin, Patrick De Mol, Marie-Pierre Hayette   +9 more
doaj   +1 more source

The shape of the iceberg: quantification of submicroscopic Plasmodium falciparum and Plasmodium vivax parasitaemia and gametocytaemia in five low endemic settings in Ethiopia

Malaria Journal, 2017
BackgroundThe widespread presence of low-density asymptomatic infections with concurrent gametocytes may be a stumbling block for malaria elimination.
F. Tadesse, L. L. van den Hoogen, Kjerstin Lanke, Jodie A. Schildkraut, K. Tetteh, A. Aseffa, H. Mamo, R. Sauerwein, I. Felger, C. Drakeley, Endalamaw Gadissa, T. Bousema   +11 more
semanticscholar   +1 more source

Phylogeny of plasmodium falciparum [PDF]

Parasitology Today, 1992
Ayala, FJ, Fitch, WM
openaire   +5 more sources

Evolutionary divergence and functional insights into the heteromeric cis‐prenyltransferase of Paramecium tetraurelia

The FEBS Journal, EarlyView.
Heteromeric cis‐prenyltransferases (CPT) are indispensable for dolichol synthesis and protein N‐glycosylation in most eukaryotes. The catalytic subunits are strongly conserved throughout evolution, in contrast to the evolutionarily variable accessory subunits. The POC1 protein from Paramecium tetraurelia is the smallest identified CPT‐accessory subunit
Agnieszka Onysk, Kamil Steczkiewicz, Mariusz Radkiewicz, Paweł Link‐Lenczowski, Przemysław Surowiecki, Karolina Sztompka, Kariona A. Grabińska, Jacek K. Nowak, Liliana Surmacz   +8 more
wiley   +1 more source

Plasmodium falciparum ligand binding to erythrocytes induce alterations in deformability essential for invasion [PDF]

, 2017
The most lethal form of malaria in humans is caused by Plasmodium falciparum. These parasites invade erythrocytes, a complex process involving multiple ligand-receptor interactions.
Cowman, Alan, Fleig, Andrea, Horgen, F. David, Malpede, Brian M, Nebl, Thomas, O\u27Neill, Joseph, Rogers, Kelly, Salinas, Nichole D, Sisquella, Xavier, Tham, Wai-Hong, Thompson, Jennifer K, Tolia, Niraj H, Whitehead, Lachlan   +12 more
core   +2 more sources

THE CULTIVATION OF THE PLASMODIUM FALCIPARUM IN VITRO [PDF]

Journal of the American Medical Association, 1914
In 1911, C. C. Bass 1 of New Orleans reported the successful cultivation of the plasmodium of malaria in vitro . He stated that he had been able to accomplish this by maintaining anaerobic conditions and a temperature of 40 C. (104 F.). Following these suggestions, Sinton 2 of London as reported in August, 1912, attempted the growth of the organisms ...
openaire   +2 more sources

Highly divergent apicomplexan cytoskeletons provide additional models for actin biology

The FEBS Journal, EarlyView.
Actin is a highly conserved, abundant and central molecule in eukaryotes. Apicomplexans contain some of the most sequence‐divergent actin cytoskeletons known. This divergence results in overlapping yet different biochemical properties. Here, we highlight the remarkable divergence of the actin cytoskeleton by comparing apicomplexan to classical systems,
Yukino Kobayashi, Ross G. Douglas
wiley   +1 more source

Plasmodium falciparum: multifaceted resistance to artemisinins

Malaria Journal, 2016
Plasmodium falciparum resistance to artemisinins, the most potent and fastest acting anti-malarials, threatens malaria elimination strategies. Artemisinin resistance is due to mutation of the PfK13 propeller domain and involves an unconventional ...
L. Paloque, A. Ramadani, O. Mercereau‐Puijalon, J. Augereau, F. Benoit‐Vical   +4 more
semanticscholar   +1 more source