Results 151 to 160 of about 296,027 (331)

Plasmodium falciparum Containment Strategy [PDF]

Medical Journal Armed Forces India, 2008
World Health Organization (WHO) estimates 1.7-2.5 million deaths and 300-500 million cases of malaria each year globally. As an initiative WHO has announced Roll Back Malaria (RBM) programme aimed at 50% reduction in deaths due to malaria by 2010. The RBM strategy recommends combination approach with prevention, care, creating sustainable demand for ...
openaire   +3 more sources

Protein tandem repeats that produce frameshifts can generate new structural states and functions

The FEBS Journal, EarlyView.
We explored an alternative protein structure landscape by analyzing amino acid sequences from frameshifted tandem repeats—regions prone to frameshifts. These frameshifts, especially in short repeats, lead to more drastic changes than in non‐repetitive regions, often altering structure, function, localization, and potentially contributing to disease ...
Zarifa Osmanli, Gudrun Aldrian, Jeremy Leclercq, Theo Falgarone, Santiago M. Gómez Bergna, Denis N. Prada Gori, Andrew V. Oleinikov, Ilham Shahmuradov, Andrey V. Kajava   +8 more
wiley   +1 more source

In silico comparative genomics analysis of Plasmodium falciparum for the identification of putative essential genes and therapeutic candidates.

, 2014
A sequence of computational methods was used for predicting novel drug targets against drug resistant malaria parasite Plasmodium falciparum. Comparative genomics, orthologous protein analysis among same and other malaria parasites and protein-protein ...
Altschul, Andrews, Anishetty, Arama, Berman, Bernstein, Bhasin, Boeckmann, Chang, Chawley, Chen, Colovos, Corpet, David Charles Warhurst, Eisenberg, Finn, Franceschini, Ghosh, Irwin, Irwin, Kanehisa, Konc, Krogh, Kushwaha, Larsen, Laskowski, Ludin, Miller, Morris, Mrutyunjay Suar, Mulder, Pieper, Pierleoni, Pontius, Rajani Kanta Mahapatra, Sali, Subhashree Rout, Sun, Tam, von Mering, Wallner, Wiederstein, World Health Organization, Yang, Yeh, Zhexin   +45 more
core   +1 more source

Evidence of Plasmodium vivax circulation in western and eastern regions of Senegal: implications for malaria control

Malaria Journal
Background Malaria elimination in Senegal requires accurate diagnosis of all Plasmodium species. Plasmodium falciparum is the most prevalent species in Senegal, although Plasmodium malariae, Plasmodium ovale, and recently Plasmodium vivax have also been ...
Aida S. Badiane, Bassirou Ngom, Tolla Ndiaye, Deirdre Cunningham, James Campbell, Amy Gaye, Aita Sène, Mouhamad Sy, Daouda Ndiaye, Davis Nwakanma, Jean Langhorne   +10 more
doaj   +1 more source

Evaluation of the rapid diagnostic test SDFK40 (Pf-pLDH/pan-pLDH) for the diagnosis of malaria in a non-endemic setting

Malaria Journal, 2011
Background The present study evaluated the SD Bioline Malaria Ag 05FK40 (SDFK40), a three-band RDT detecting Plasmodium falciparum-specific parasite lactate dehydrogenase (Pf-pLDH) and pan Plasmodium-specific pLDH (pan-pLDH), in a reference setting ...
Van Esbroeck Marjan, Bottieau Emmanuel, Cnops Lieselotte, Gillet Philippe, Maltha Jessica, Bruggeman Cathrien, Jacobs Jan   +6 more
doaj   +1 more source

Observations on an apparent chloroquine-resistant strain of Plasmodium falciparum in West Africa. [PDF]

, 1965
E. E. Lasch, T. L. N'Guyen
openalex   +1 more source

New Evidence of TLR4 and TLR9 Variants Influencing Parasitaemia and Symptoms of Plasmodium vivax Infection

International Journal of Immunogenetics, EarlyView.
ABSTRACT Toll‐like receptors (TLRs) induce the production of pro‐inflammatory cytokines and regulate the immune response to Plasmodium vivax infection. Genetic variants of TLRs are associated with susceptibility and severity of malaria in different populations. This study aimed to evaluate the association between polymorphisms in TLR1, TLR4, TLR7, TLR8,
Mikaele Monik Rodrigues Inácio Silva, Gabriela Maria Andrade Correia, Juliana Dal‐Ri Lindenau, Maristela Gomes Cunha, Maria Deise Oliveira Ohnishi, Ana Maria Revoredo Silva Ventura, Ândrea Ribeiro‐dos‐Santos, Mara Helena Hutz, Vinicius Albuquerque Sortica   +8 more
wiley   +1 more source

Assessing the burden of submicroscopic Plasmodium infections in a pre-elimination malaria setting in sub-Saharan Africa, Guinea-Bissau

Malaria Journal
Background Submicroscopic Plasmodium infections can be a source of persistent malaria transmission. The aim of this study was to assess their frequency, distribution, morbidity and associated factors in a pre-elimination malaria setting in sub-Saharan ...
Ronise Silva, Luis Filipe Lopes, Amabelia Rodrigues, Ana Paula Arez, Márcia M. Medeiros   +4 more
doaj   +1 more source

Sero-identification of the aetiologies of human malaria exposure (Plasmodium spp.) in the Limu Kossa District of Jimma Zone, South western Ethiopia

Malaria Journal, 2019
Background Malaria remains a very important public health problem in Ethiopia. Currently, only Plasmodium falciparum and Plasmodium vivax are considered in the malaria diagnostic and treatment policies. However, the existence and prevalence of Plasmodium
Sindew Mekasha Feleke, Bokretsion Gidey Brhane, Hassen Mamo, Ashenafi Assefa, Adugna Woyessa, Guilherme Maerschner Ogawa, Vitaliano Cama   +6 more
doaj   +1 more source

Characteristics of Four New Drug-Resistant Strains of Plasmodium falciparum from South-East Asia [PDF]

, 1969
D. F. Clyde, A. T. Dawkins, G. G. Heiner, Vincent C. McCarthy, R. B. Hornick   +4 more
openalex   +1 more source