Results 161 to 170 of about 192,328 (309)
Scientific ReportsMalaria has been a leading cause of death in human populations for centuries and remains a major public health challenge in African countries, especially affecting children. Among the five Plasmodium species infecting humans, Plasmodium falciparum is the
Alejandro Llanos-Lizcano +10 more
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Quaternary ammonium compounds efficiently inhibit Plasmodium falciparum growth in vitro by impairment of choline transport [PDF]
, 1986 Marie‐Laure Ancelin, Henri Vial
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Photodynamic therapy of cancer‐associated infections
Photochemistry and Photobiology, EarlyView.Pathogens can be involved in tumor initiation, promotion and progression through different mechanisms, and their treatment can prevent new cancer cases, improve outcomes, and revert poor‐prognostic phenotypes. Photodynamic therapy (PDT) successfully treats different types of cancers and infections, and, therefore, has a unique potential to address ...
Giulia Kassab, Juan Chen, Gang Zheng
wiley +1 more source
Generating Focussed Molecule Libraries for Drug Discovery with Recurrent Neural Networks [PDF]
arXiv, 2017 In de novo drug design, computational strategies are used to generate novel molecules with good affinity to the desired biological target. In this work, we show that recurrent neural networks can be trained as generative models for molecular structures, similar to statistical language models in natural language processing.
arxiv
Tropical Medicine &International Health, EarlyView.Abstract Objectives Prior to 2017, Odisha accounted for 50% of all Plasmodium falciparum cases in India. The ‘National Strategic Plan’ for malaria elimination had distributed 11.3 million insecticidal treated nets (ITNs) to 23 million individuals in Odisha's 17 malaria‐endemic districts by 2017.
A. N. Shriram +6 more
wiley +1 more source
Brazilian Journal of Infectious Diseases, 2013 Plasmodium vivax and Plasmodium falciparum are becoming resistant to drugs including antifolates, sulphonamides and chloroquine. This study was focused at sequence analysis of resistant genes of these parasites against sulphadoxine–pyrimethamine and ...
Lubna Khatoon +3 more
doaj
Mass Spectrometry Reviews, Volume 44, Issue 3, Page 213-453, May/June 2025.Abstract The use of matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this review is the 12th update of the original article published in 1999 and brings coverage of the literature to the end of 2022.
David J. Harvey
wiley +1 more source
A Geostatistical Framework for Combining Spatially Referenced Disease Prevalence Data from Multiple Diagnostics [PDF]
arXiv, 2018 Multiple diagnostic tests are often used due to limited resources or because they provide complementary information on the epidemiology of a disease under investigation. Existing statistical methods to combine prevalence data from multiple diagnostics ignore the potential over-dispersion induced by the spatial correlations in the data.
arxiv
Identification of the acidic compartment of Plasmodium falciparum-infected human erythrocytes as the target of the antimalarial drug chloroquine. [PDF]
, 1984 Avner Yayon +2 more
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