Results 161 to 170 of about 296,027 (331)

Molecular Testing in Sickle Cell Disease: From Newborn Screening to Transfusion Care

open access: yesInternational Journal of Laboratory Hematology, EarlyView.
ABSTRACT Sickle cell disease (SCD) is one of the most frequent monogenic diseases worldwide and a highly heterogeneous and complex disease. SCD care carries several challenges. This includes early and accurate diagnosis as well as optimal red blood cell transfusion matching in this population carrying a high risk of alloimmunization.
Thomas Pincez, Yves D. Pastore
wiley   +1 more source

Molecular Detection of Malaria in South Punjab with Higher Proportion of Mixed Infections

open access: yesIranian Journal of Parasitology, 2014
Background: Malaria is well known for its fatalities worldwide, Plasmodium vivax and the Plasmodium falciparum are the two important species of malaria reported from Pakistan and creating lots of morbidities across the country.
Saba Shahzadi   +5 more
doaj  

Imaging malaria parasites across scales and time

open access: yesJournal of Microscopy, EarlyView.
Abstract The idea that disease is caused at the cellular level is so fundamental to us that we might forget the critical role microscopy played in generating and developing this insight. Visually identifying diseased or infected cells lays the foundation for any effort to curb human pathology.
Julien Guizetti
wiley   +1 more source

Artificial intelligence‐powered microscopy: Transforming the landscape of parasitology

open access: yesJournal of Microscopy, EarlyView.
Abstract Microscopy and image analysis play a vital role in parasitology research; they are critical for identifying parasitic organisms and elucidating their complex life cycles. Despite major advancements in imaging and analysis, several challenges remain. These include the integration of interdisciplinary data; information derived from various model
Mariana De Niz   +4 more
wiley   +1 more source

Ultra-Sensitive Detection of Plasmodium falciparum by Amplification of Multi-Copy Subtelomeric Targets

open access: yesPLoS Medicine, 2015
Background Planning and evaluating malaria control strategies relies on accurate definition of parasite prevalence in the population. A large proportion of asymptomatic parasite infections can only be identified by surveillance with molecular methods ...
Natalie E Hofmann   +5 more
semanticscholar   +1 more source

Optimisation of freeze substitution protocols for the examination of malaria parasite structure by volumetric electron microscopy

open access: yesJournal of Microscopy, EarlyView.
Abstract Malaria is one of the deadliest infectious diseases in the world, annually responsible for over 400,000 deaths. It is caused by parasites of the genus Plasmodium, which undergo remarkable structural changes during their development within different cells across various hosts.
Rachel Rachid   +3 more
wiley   +1 more source

Comparative attraction of Anopheles quadriannulatus and Anopheles arabiensis to humans estimated by comparing their relative abundance in samples of mosquito larvae and adults collected across an ecologically heterogeneous landscape in southern Tanzania Utafiti wa kulinganisha mvuto wa mbu aina ya Anopheles arabiensis na Anopheles quadriannulatus kwa binadamu katika mandhari yenye mazingira mbalimbali kusini mwa Tanzania

open access: yesMedical and Veterinary Entomology, EarlyView.
Light and barrier traps near human activity selectively captured more Anopheles arabiensis, indicating a strong attraction to humans and explicit bias in adult sampling methods. Traps placed in open glades away from humans captured species proportions similar to larval samples, suggesting reduced sampling bias in those settings. Visits by entomological
Deogratius R. Kavishe   +8 more
wiley   +1 more source

Intra-individual variability in ancient plasmodium DNA recovery highlights need for enhanced sampling

open access: yesScientific Reports
Malaria has been a leading cause of death in human populations for centuries and remains a major public health challenge in African countries, especially affecting children. Among the five Plasmodium species infecting humans, Plasmodium falciparum is the
Alejandro Llanos-Lizcano   +10 more
doaj   +1 more source

Identification of two integral membrane proteins of Plasmodium falciparum. [PDF]

open access: green, 1988
Jason A. Smythe   +5 more
openalex   +1 more source

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