Results 211 to 220 of about 113,438 (254)

Plasmodium falciparum: Attenuation by irradiation

Experimental Parasitology, 1983
The effect of irradiation on the in vitro growth of Plasmodium falciparum was investigated. The cultured malarial parasites at selected stages of development were exposed to gamma rays and the sensitivity of each stage was determined. The stages most sensitive to irradiation were the ring forms and the early trophozoites; late trophozoites were ...
S, Waki, I, Yonome, M, Suzuki
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Mating Patterns of Plasmodium falciparum

Parasitology Today, 1998
Recent empirical data have enabled a more informed debate over the extent of clonality in Plasmodium falciparum populations. Oocyst heterozygosity data reveal that the mating structure of malaria populations varies according to the transmission intensity.
R E, Paul, K P, Day
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Antibodies and Plasmodium falciparum merozoites

Trends in Parasitology, 2001
There is considerable interest in using merozoite proteins in a vaccine against falciparum malaria. Observations that antibodies to merozoite surface proteins block invasion are a basis for optimism. This article draws attention to important and varied aspects of how antibodies to Plasmodium falciparum merozoites affect red blood cell invasion.
R, Ramasamy, M, Ramasamy, S, Yasawardena
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Chloroquine Resistance in Plasmodium Falciparum

The American Journal of Tropical Medicine and Hygiene, 1961
Summary The response to chloroquine of a strain of Plasmodium falciparum malaria from Colombia, South America, has been studied in seven patients. Six of these infections responded poorly to normal (0.6 gram, 1.5 grams) and above normal (2.1 grams) doses of the drug. The parasites were either not cleared from the blood stream or were eliminated slowly,
M D, YOUNG, D V, MOORE
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The Plasmodium falciparum Genome Project

Parasitology Today, 1998
National Center for Biotechnology Information (NCBI) BLAST searches on Apicomplexan sequence data◦http://www.ncbi.nlm.nih.gov/Malaria/Malaria Genetics Section; NIAID/NIH◦www.ncbi.nlm.nih.gov/malaria/NIAID malaria research and reference reagent repository◦http://www.niaid.nih.gov/reposit/malrep.htmMalaria Genome Mapping Data; WEHI/Monash University◦http:
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UvrD helicase of Plasmodium falciparum

Gene, 2008
Malaria caused by the mosquito-transmitted parasite Plasmodium is the cause of enormous number of deaths every year in the tropical and subtropical areas of the world. Among four species of Plasmodium, Plasmodium falciparum causes most fatal form of malaria. With time, the parasite has developed insecticide and drug resistance.
Jay, Shankar, Renu, Tuteja
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Genetic Diversity in Plasmodium falciparum

1990
Publisher Summary This chapter focuses on those forms of genetic diversity that are clearly understood at the deoxyribonucleic acid (DNA) level. The application of recombinant DNA technology to the study of Plasmodium falciparum and other species of Plasmodium has resulted in rapid advances in the understanding of genetic diversity in malaria ...
D J, Kemp, A F, Cowman, D, Walliker
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Plasmodium falciparum-induced channels

International Journal for Parasitology, 2004
To survive within a red blood cell, the malaria parasite alters dramatically the permeability of the host's plasma membrane (allowing the uptake of essential nutrients and the removal of potentially hazardous metabolites). The pathway(s) responsible for the increased permeability have been proposed as putative chemotherapeutic targets and/or selective ...
Henry M, Staines, Trevor, Powell, Serge L Y, Thomas, J Clive, Ellory   +3 more
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Commitment to Gametocytogenesis in Plasmodium falciparum

Parasitology Today, 2000
To achieve transmission, a subpopulation of asexually dividing bloodstream forms of the human malaria parasite Plasmodium falciparum withdraws from the cell cycle to develop into gametocytes - cells specialized for sexual reproduction and invasion of the mosquito vector.
M, Dyer, K P, Day
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Mefloquine resistance in Plasmodium falciparum

Parasitology Today, 1995
Mefloquine resistance in Plasmodium falciparum, the most dangerous of the four pathogenic malaria parasites of humans, is established in several endemic regions of the world. After a promising start, resistance has developed to disturbing extents in some areas, whereas in many regions it remains an effective drug.
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