A randomised trial of an eight-week, once weekly primaquine regimen to prevent relapse of plasmodium vivax in Northwest Frontier Province, Pakistan. [PDF]
BACKGROUND: Vivax malaria remains a major cause of morbidity in the subtropics. To undermine the stability of the disease, drugs are required that prevent relapse and provide reservoir reduction. A 14-day course of primaquine (PQ) is effective but cannot
Erasmus, Panna+6 more
core +8 more sources
Suppression of Plasmodium falciparum by serum collected from a case of Plasmodium vivax infection. [PDF]
BACKGROUND: It has frequently been reported that Plasmodium vivax suppressed Plasmodium falciparum and ameliorated disease severity in patients infected with these two species simultaneously.
Chavalitshewinkoon-Petmitr, Porntip+9 more
core +3 more sources
Tackling resistance: Emerging antimalarials and new parasite targets in the era of elimination [version 1; referees: 2 approved] [PDF]
Malaria remains a significant contributor to global human mortality, and roughly half the world’s population is at risk for infection with Plasmodium spp. parasites.
Matthews, Emily S, Odom John, Audrey R
core +2 more sources
Insights into the invasion biology of Plasmodium vivax [PDF]
Plasmodium vivax is the most widely distributed human malaria parasite outside sub Sahara regions of Africa causing huge morbidity and occasionally being severe and fatal (Kochar et al., 2005; Tjitra et al., 2008). Invasion of host erythrocytes is essential for development of disease and the process varies greatly among different malaria parasites ...
Om P. Singh, Surendra K Prajapati
openaire +4 more sources
Human Infections with Plasmodium knowlesi, the Philippines. [PDF]
Five human cases of infection with the simian malaria parasite Plasmodium knowlesi from Palawan, the Philippines, were confirmed by nested PCR. This study suggests that this zoonotic infection is found across a relatively wide area in Palawan and ...
Bell, David+9 more
core +3 more sources
PLASMODIUM VIVAX BLOOD-STAGE DYNAMICS [PDF]
We examine the dynamics of parasitemia and gametocytemia reflected in the preintervention charts of 221 malaria-naive U.S. neurosyphilis patients infected with the St. Elizabeth strain of Plasmodium vivax, for malariatherapy, focusing on the 109 charts for which 15 or more days of patency preceded intervention and daily records encompassed an average ...
F. Ellis McKenzie+4 more
openaire +3 more sources
Detecting signatures of balancing selection to identify targets of anti-parasite immunity.
Parasite antigen genes might evolve under frequency-dependent immune selection. The distinctive patterns of polymorphism that result can be detected using population genetic methods that test for signatures of balancing selection, allowing genes encoding
Conway, David J, Weedall, Gareth D
core +1 more source
Duffy phenotype and plasmodium vivax infections in humans and Apes, Africa [PDF]
info:eu-repo/semantics ...
Culleton, Richard Leighton+1 more
core +4 more sources
Severe Plasmodium vivax infection in Korea [PDF]
Although severe malaria by Plasmodium vivax has been increasingly reported, there are marked variations in the type and rate of the complications by geographic area. This is possibly because of the presence of concurrent falciparum malaria or bacteraemia, and of differences in underlying immune status among the infected subjects. Furthermore, published
Areum Durey+7 more
openaire +3 more sources
Malaria "diagnosis" and diagnostics in Afghanistan. [PDF]
In many malaria-endemic areas, including Afghanistan, overdiagnosis of malaria is common. Even when using parasite-based diagnostic tests prior to treatment, clinicians commonly prescribe antimalarial treatment following negative test results.
Ahmad, Tamanna+13 more
core +1 more source