Results 61 to 70 of about 108,718 (219)

Rosette formation by Plasmodium vivax

Transactions of the Royal Society of Tropical Medicine and Hygiene, 1995
In contrast to Plasmodium falciparum, infections with P. vivax are seldom fatal. Red blood cells containing mature forms of P. falciparum sequester in the microvasculature of vital organs, and adhere to vascular endothelium (cytoadherence) and to uninfected red cells (rosetting). Rosetting of P.
Udomsanpetch, R, Thanikkul, K, Pukrittayakamee, S, White, N   +3 more
openaire   +3 more sources

Molecular detection of drug resistant malaria in Southern Thailand

Malaria Journal, 2019
Background Drug resistance within the major malaria parasites Plasmodium vivax and Plasmodium falciparum threatens malaria control and elimination in Southeast Asia.
Chaturong Noisang, Christiane Prosser, Wieland Meyer, Waenurama Chemoh, John Ellis, Nongyao Sawangjaroen, Rogan Lee   +6 more
doaj   +1 more source

Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future

Medicinal Research Reviews, EarlyView.
ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley   +1 more source

GAMETOCYTEMIA IN PLASMODIUM VIVAX AND PLASMODIUM FALCIPARUM INFECTIONS [PDF]

Journal of Parasitology, 2006
Two expert research microscopists, each blinded to the other's reports, diagnosed single-species malaria infections in 2,141 adults presenting at outpatient malaria clinics in Tak Province, Thailand, and Iquitos, Peru, in May-August 1998, May-July 1999, and May-June 2001.
F Ellis, Mckenzie, Chansuda, Wongsrichanalai, Alan J, Magill, J Russ, Forney, Barnyen, Permpanich, Carmen, Lucas, Laura M, Erhart, Wendy P, O'Meara, David L, Smith, Jeeraphat, Sirichaisinthop, Robert A, Gasser   +10 more
openaire   +2 more sources

Apigenin Protects Hypertensive Intracerebral Hemorrhage by Regulating Trx1 Through Binding to PRDX2

Phytotherapy Research, EarlyView.
ABSTRACT Intracerebral hemorrhage (ICH) remains the most severe stroke subtype with high mortality and disability rates. Although apigenin has shown cerebroprotective potential in preclinical studies, its mechanism of action, particularly in hypertensive ICH, remains poorly understood.
Hao‐chen Xu, Ming Liu, Ying‐ying Sun, Jie‐Dan Ping, Qing‐hua Cui, Jing‐zhou Chen, Hao Li   +6 more
wiley   +1 more source

Transgenic selection and underlying mechanisms in apicomplexan parasites

The FEBS Journal, EarlyView.
Transgenic selection markers have driven genetic engineering in apicomplexans, enabling precise, iterative experiments. This review discusses mechanistic details of drug selection markers, strategies for marker recycling, and practical considerations for several clinically relevant parasites.
Swaroop Peddiraju, Rakhee Lohia, Nishith Gupta   +2 more
wiley   +1 more source

Strategies for understanding and reducing the Plasmodium vivax and Plasmodium ovale hypnozoite reservoir in Papua New Guinean children : a randomised placebo-controlled trial and mathematical model [PDF]

, 2015
The undetectable hypnozoite reservoir for relapsing Plasmodium vivax and P. ovale malarias presents a major challenge for malaria control and elimination in endemic countries.
Bassat Orellana, Quique, Waltmann, A, Mariabeth Silkey (818706), Bassat, Q, Samol, Lornah, Waltmann, Andreea, Quique Bassat (89288), Silkey, Maribeth, Kiniboro, Benson, Ingrid Felger, Peter M. Siba (136849), Benson Kinboro, Felger, I, Natalie E Hofmann, Leanne J. Robinson (137914), Brewster, J, Silkey, Mariabeth, Wampfler, R, Li Wai Suen, Connie S. N., Mariabeth Silkey, Schofield, Louis, Tarongka, Nandao, Suen, Connie S.N. Li Wai, Siba, Peter, Hofmann, Natalie E., Betuela, Inoni, Mueller, I, Siba, PM, Michael T White, Stephan Karl, Inoni Betuela, Wampfler, Rahel, Betuela, I, Nandao Tarongka, Nandao Tarongka (175175), Robinson, Leanne J., Andreea Waltmann (742598), Schofield, L, Peter M Siba, Kinboro, Benson, Ingrid Felger (92160), Andreea Waltmann, Connie S. N. Li Wai Suen (455802), Robinson, LJ, Brewster, Jessica, White, Michael T., Kinboro, B, Michael T. White (402788), Natalie E. Hofmann (818703), Karl, Stephan, Felger, Ingrid, Li Wai Suen, CSN, Stephan Karl (46605), Lorry, L, Ivo Mueller (46609), Silkey, M, Tarongka, N, Jessica Brewster (733968), Samol, Loenah, Karl, S, Mueller, Ivo, Louis Schofield, White, MT, Ivo Mueller, Connie S N Li Wai Suen, Bassat, Quique, Rahel Wampfler (464173), Lornah Samol (818705), Lorry, Lina, Samol, L, Benson Kinboro (818704), Lornah Samol, Leanne J Robinson, Quique Bassat, Inoni Betuela (67110), Siba, Peter M., Li Wai Suen, C, Hofmann, NE, Rahel Wampfler, Jessica Brewster, Louis Schofield (175187), Lina Lorry, Lina Lorry (680187)   +82 more
core   +1 more source

Validation of Health Belief Model and Theory of Planned Behaviour Constructs for Predicting Malaria Vaccine Acceptance in Ghana: A Partial Least Squares Structural Equation Modelling Approach

Tropical Medicine &International Health, EarlyView.
ABSTRACT Aim This study examines the predictive power of constructs from the health belief model (HBM) and theory of planned behaviour (TPB) in explaining malaria vaccine acceptance in Ghana in the post‐COVID‐19 era, while also assessing the reliability of these constructs within this context.
Michael Sarfo, Michael Snowden, Jamie P. Halsall   +2 more
wiley   +1 more source

Plasmodium vivax Malaria in Cambodia [PDF]

The American Journal of Tropical Medicine and Hygiene, 2016
The Cambodian National Strategic Plan for Elimination of Malaria aims to move step by step toward elimination of malaria across Cambodia with an initial focus on Plasmodium falciparum malaria before achieving elimination of all forms of malaria, including Plasmodium vivax in 2025. The emergence of artemisinin-resistant P. falciparum in western Cambodia
Siv, Sovannaroth, Roca-Feltrer, Arantxa, Vinjamuri, Seshu Babu, Bouth, Denis Mey, Lek, Dysoley, Rashid, Mohammad Abdur, By, Ngau Peng, Popovici, Jean, Huy, Rekol, Menard, Didier   +9 more
openaire   +2 more sources

Plasmodium falciparum Parasites With Histidine‐Rich Protein 2 (pfhrp2) and pfhrp3 Gene Deletions in Frontier Endemic Regions of Brazilian Amazon

Tropical Medicine &International Health, EarlyView.
ABSTRACT Studies reporting deletions of the pfhrp2 and pfhrp3 genes in P. falciparum populations in various malaria‐endemic countries, including countries bordering Brazil, are increasing. Individuals infected with P. falciparum carrying deletions of the pfhrp2/3 genes may yield false‐negative results in Rapid Diagnostic Tests (RDTs) based on the ...
Jéssica de Oliveira Bonsanto Gonçalves, Simone da Silva Santos, Rodrigo Medeiros Martorano, Jaime Louzada, Victoria Martins Roque Almeida, Lucas Rego Viana, Josely Oliveira Ferreira, Anielle Pina Costa, André Siqueira, Martha Cecília Suárez‐Mutis   +9 more
wiley   +1 more source