Results 61 to 70 of about 27,835 (183)

Plasmodium vivax treatments [PDF]

Current Opinion in Infectious Diseases, 2011
For over 50 years, the treatment of Plasmodium vivax has relied on a combination of chloroquine and primaquine, but this strategy is under threat. Chloroquine efficacy is now compromised across much of the vivax endemic world and there are significant operational difficulties in deploying primaquine. We review the recent advances in P.
Price, R, Douglas, N, Anstey, N, von Seidlein, L   +3 more
openaire   +3 more sources

Molecular identification of Plasmodium species responsible for malaria reveals Plasmodium vivax isolates in Duffy negative individuals from southwestern Nigeria

Malaria Journal, 2018
Background Malaria in Nigeria is principally due to Plasmodium falciparum and, to a lesser extent to Plasmodium malariae and Plasmodium ovale. Plasmodium vivax is thought to be absent in Nigeria in particular and sub-Saharan Africa in general, due to the
Mary Aigbiremo Oboh, Aida Sadikh Badiane, Godwin Ntadom, Yaye Die Ndiaye, Khadim Diongue, Mamadou Alpha Diallo, Daouda Ndiaye   +6 more
doaj   +1 more source

Structural Insights Into the Function of Leishmania major Adenylosuccinate Lyase

Proteins: Structure, Function, and Bioinformatics, Volume 94, Issue 10, Page 1686-1701, October 2026.
ABSTRACT One of several intriguing aspects of kinetoplastid biochemistry is the complete dependence on host purines and purine recycling due to the lack of a de novo purine biosynthesis pathway. Adenylosuccinate lyase (ASL, EC 4.3.2.2) is a key enzyme in the purine synthesis pathway responsible for the conversion of adenylosuccinate into adenosine ...
Ivan R. e Silva, Monique Mantovani, Maria E. S. D. Lino, Aline O. Albuquerque, João H. M. da Silva, Ronaldo A. P. Nagem, Adriana L. Rojas, Geraldo R. Sartori, Eduardo Horjales, David Campbell, Otavio H. Thiemann   +10 more
wiley   +1 more source

The detection of cryptic Plasmodium infection among villagers in Attapeu province, Lao PDR.

PLoS Neglected Tropical Diseases, 2017
BackgroundAlthough the malaria burden in the Lao PDR has gradually decreased, the elimination of malaria by 2030 presents many challenges. Microscopy and malaria rapid diagnostic tests (RDTs) are used to diagnose malaria in the Lao PDR; however, some ...
Moritoshi Iwagami, Sengdeuane Keomalaphet, Phonepadith Khattignavong, Pheovaly Soundala, Lavy Lorphachan, Emilie Matsumoto-Takahashi, Michel Strobel, Daniel Reinharz, Manisack Phommasansack, Bouasy Hongvanthong, Paul T Brey, Shigeyuki Kano   +11 more
doaj   +1 more source

Validation of Health Belief Model and Theory of Planned Behaviour Constructs for Predicting Malaria Vaccine Acceptance in Ghana: A Partial Least Squares Structural Equation Modelling Approach

Tropical Medicine &International Health, Volume 31, Issue 10, Page 1443-1452, October 2026.
ABSTRACT Aim This study examines the predictive power of constructs from the health belief model (HBM) and theory of planned behaviour (TPB) in explaining malaria vaccine acceptance in Ghana in the post‐COVID‐19 era, while also assessing the reliability of these constructs within this context.
Michael Sarfo, Michael Snowden, Jamie P. Halsall   +2 more
wiley   +1 more source

Malária vivax com tempo de incubação prolongado, detectada no Distrito Federal: relato de três casos Vivax malaria with long incubation period, detected in the Federal District: three case reports

Revista da Sociedade Brasileira de Medicina Tropical, 2010
Foram detectados três casos de malária vivax em Brasília, Distrito Federal, área considerada indene, procedentes da Amazônia, seis meses após estarem residindo em Brasília. Período de incubação prolongado tem sido descrito apenas para infecções por cepas
Pedro Luiz Tauil, Francisco das Chagas de Oliveira Luz, Anna Paula Lopes de Oliveira, Fernando Augusto Lopes Deckers, João Barberino Santos   +4 more
doaj   +1 more source

Peptide‐Enabled Nanoplatforms for Malaria and Leishmaniasis: From Intracellular Targeting to Translational Diagnostic Perspectives

ChemMedChem, Volume 21, Issue 18, 28 September 2026.
Peptide‐enabled nanoplatforms offer multifunctional strategies for the treatment and diagnosis of malaria and leishmaniasis. Liposomal, polymeric, and metallic nanocarriers, together with cell‐penetrating peptides and parasite‐derived mimotopes, can improve targeted drug delivery, stability, bioavailability, and intracellular localization.
Christian S. Carnero Canales, Ana Clara Lunardi Yagi, Túlio Custódio Reis, Jessica Ingrid Cazorla, Jade Rojas Villar, Marcia A. Graminha, Roxana Yesenia Pastrana Alta, Fernando Rogério Pavan   +7 more
wiley   +1 more source

Imported Plasmodium vivax Malaria in the Russian Federation from Western Sub-Saharan Africa

Journal of Tropical Medicine, 2019
Background. Imported cases of Plasmodium vivax malaria from western Africa are reported annually in the Russian Federation. Infected native African people moving from western Africa for different purposes (students, businessmen, specialists, etc.) or ...
Alla Baranova, Vladimir Sergiev, Lola Morozova, Natalia Turbabina, Evgeny Morozov   +4 more
doaj   +1 more source

Insights into the Cytoadherence Phenomenon of Plasmodium vivax: The Putative Role of Phosphatidylserine

Frontiers in Immunology, 2017
Plasmodium vivax is the most geographically widespread and the dominant human malaria parasite in most countries outside of sub-Saharan Africa and, although it was classically recognized to cause benign infection, severe cases and deaths caused by P ...
Paulo Renato Totino, Stefanie Costa Lopes   +1 more
doaj   +1 more source

Malaria‐Associated Secondary Hematophagocytic Lymphohistocytosis—A Case Report and Comprehensive Literature Review (sHLH)

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Malaria‐associated secondary HLH, though rare, is often overlooked. Clinicians should maintain a high‐index of suspicion in travelers returning from malaria‐endemic regions who develop severe to rapidly worsening inflammatory illness, as early recognition is critical for survival.
Indresh Yadav, Sulav Kumar Jha, Sweta Singh, Dipesh Kumar Mandal, Saurav Jha   +4 more
wiley   +1 more source