Results 81 to 90 of about 827,739 (268)
Environmental Research Letters, 2017 Packaged water consumption is growing in low- and middle-income countries, but the magnitude of this phenomenon and its environmental consequences remain unclear.
Nicola A Wardrop +5 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Effect of Bacteriophages against Biofilms of Escherichia coli on Food Processing Surfaces
MicroorganismsThe bacterial adhesion to food processing surfaces is a threat to human health, as these surfaces can serve as reservoirs of pathogenic bacteria. Escherichia coli is an easily biofilm-forming bacterium involved in surface contamination that can lead to ...
Ana Brás +5 more
doaj +1 more source
Journal of the Japan Welding Society, 1959 Experimental studies were made concerning to the annealing and corrosion of the welded P.V.C. plate of 2 nun in thickness. Effects of radiation to the mechanical properties of these materials were also performd.Tensile strength of welded P.V.C. is decreased by the corrosion of H2SO4 HCl and HNO3, and is increased gradually with annealing time.Although ...
I. Onishi, H. Kimura
openaire +7 more sources
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Imagem corporal e qualidade de vida após explante mamário
Revista Brasileira de Cirurgia PlásticaIntrodução Os implantes mamários de silicone foram introduzidos na prática cirúrgica na década de 1960 e são muito utilizados desde então, mas com porcentagem cada vez menor entre as cirurgias estéticas e com aumento da explantação.
Raissa Barakatt de Figueiredo +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
EFSA Journal, 2017 This scientific opinion of the EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF Panel) deals with the safety evaluation of the recycling process PEGRA‐V (EU register number RECYC0137), which is based on the Starlinger ...
Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF) +26 more
doaj +1 more source