Results 51 to 60 of about 2,659,705 (305)

Interchangeable core and cavity plates for two-plate family injection mould

Journal of Mechanical Engineering and Sciences, 2017
This study modified a two-plate family plastic injection mould to become interchangeable by changing the core and cavity plates using an existing mould base.
M. A. M. Ali, N. Idayu, Z. Abdullah, M. H. A. Bakar, S. Sivarao, M. S. A. Aziz, A. Abdullah   +6 more
doaj   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

Data mining for fault diagnostics: A case for plastic injection molding

Procedia CIRP, 2019
In manufacturing processes the automated identification of faulty operating conditions that might lead to insufficient product quality and reduced availability of the equipment is an important and challenging task.
Dominik Kozjek, Rok Vrabič, D. Kralj, P. Butala, N. Lavrač   +4 more
semanticscholar   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source

Design of hybrid deep learning using TSA with ANN for cost evaluation in the plastic injection industry

Frontiers in Mechanical Engineering
In the plastic injection industry, plastic injection molding is one of the most extensively used mass production technologies and has been continuously increasing in recent years.
Athakorn Kengpol, Pornthip Tabkosai
doaj   +1 more source

Identifikasi Cacat Produk Dan Kerusakan Mold Pada Proses Plastic Injection Molding

Jurnal Teknologi dan Riset Terapan (JATRA), 2019
Mold (cetakan) merupakan perkakas pada proses injection molding untuk membuat produk dari plastik. Akibat penggunaan selama proses produksinya, mold ini dapat mengalami kerusakan yang mengakibatkan terjadinya cacat pada produk.
Hanifah Widiastuti, Saprin Epraim Surbakti, F. Restu, Muhammad Hasan Albana, Ihsan Saputra   +4 more
semanticscholar   +1 more source

Enabling Digital Continuity in Virtual Manufacturing for Eco‐Efficiency Assessment of Lightweight Structures by Means of a Domain‐Specific Structural Mechanics Language: Requirements, Idea and Proof of Concept

Advanced Engineering Materials, EarlyView.
This article presents a solver‐agnostic domain‐specific language (DSL) for computational structural mechanics that strengthens interoperability in virtual product development. Using a hierarchical data model, the DSL enables seamless exchange between diverse simulation tools and numerical methods.
Martin Rädel, Andreas Schuster, Felix Schoenitz, Jean Lefèvre   +3 more
wiley   +1 more source

Optimization Parameters to Reduce the Warpage Defect of Plastic Injection Molding Process for A Thin-Shell Part Using Design of Experiment

IOP Conference Series: Materials Science and Engineering, 2019
Development of light, small and thin plastic products that possess high strength characteristic such as electronic devices have become one of the tremendous demands in the plastic injection molding industry nowadays.
H. Radhwan, S. Nasir, M. Rashidi, K. Kamarudin, Abdellah El-hadj Abdellah   +4 more
semanticscholar   +1 more source