Results 111 to 120 of about 14,949 (262)

3D ultimate limit state analysis using discontinuity layout optimization [PDF]

open access: yes, 2012
The recently developed discontinuity layout optimization (DLO) procedure uses limit analysis theory to directly obtain upper bounds on plane strain collapse loads of bodies and has successfully been applied to geotechnical problems.
Hawksbee, Samuel John
core  

A Proposed Approach for Plastic Limit Determination Using the Drop-Cone Penetrometer Device

open access: yesJournal of Engineering and Sustainable Development, 2008
The drop-cone method, in which a 30° cone of mass 80 g is allowed to penetrate into a soil sample at any moisture contents, was used to determine the plastic limit for more than 160 natural samples representing a wide range of soil type with different ...
Mohammed Hussein Al-Dahlaki   +1 more
doaj  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Ratchet analysis of structures under a generalised cyclic load history

open access: yes, 2014
This paper introduces a new approach based upon the Linear Matching Method in order to obtain the ratchet limit of structures subjected to an arbitrary thermo-mechanical load history. This method varies from the traditional Linear Matching Method ratchet
Lytwyn, Michael   +5 more
core   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Buckling resistance assessment of thin-walled open section element under pure compression

open access: yesMATEC Web of Conferences, 2016
The paper deals with the problem of buckling resistance determination in case of perforated thin-walled elements. Depending on element slenderness the limit load in compression mode may be determined taking into account elastic (LBA analysis), elasto ...
Piotrowski Andrzej   +4 more
doaj   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

open access: yesFEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu   +10 more
wiley   +1 more source

Plastic collapse of pipe bends under combined internal pressure and in-plane bending

open access: yes, 2005
Plastic collapse of pipe bends with attached straight pipes under combined internal pressure and in-plane closing moment is investigated by elastic–plastic finite element analysis.
Robertson, A.C., Mackenzie, D., Li, H.
core   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

open access: yesFEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa   +2 more
wiley   +1 more source

Shakedown behaviour of composite cylinders with cross holes

open access: yes, 2010
In this study, both the lower and upper bound shakedown limits of a closed-end composite cylinder with or without a cross hole subject to constant internal pressure and a cyclic thermal gradient are calculated by the Linear Matching Method (LMM ...
Ure, James Michael   +3 more
core  

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