Results 21 to 30 of about 419,145 (267)

Signaling plasticity in the integrated stress response

open access: yesFrontiers in Cell and Developmental Biology, 2023
The Integrated Stress Response (ISR) is an essential homeostatic signaling network that controls the cell’s biosynthetic capacity. Four ISR sensor kinases detect multiple stressors and relay this information to downstream effectors by phosphorylating a common node: the alpha subunit of the eukaryotic initiation factor eIF2. As a result, general protein
Morgane Boone, Francesca Zappa
openaire   +3 more sources

Unified plastic solutions to a circular tunnel under two-way unequal pressures and their applications

open access: yesYantu gongcheng xuebao, 2022
Various unified plastic solutions to a circular tunnel under two-way unequal pressures are presented corresponding with the in-situ stress distributions, such as the stress, displacement and radius of plastic zone and the ground response curve, where the
ZENG Kai-hua 1, LI Xue-jun 1, LU Shou-shan 2, LI Han-long 1
doaj   +1 more source

Plasticity in climate change responses

open access: yesBiological Reviews
ABSTRACT Recent research has shown that climate change can both induce and modulate the expression of plastic traits but our understanding of the role of phenotypic plasticity as an adaptive response to climate change is limited.
Stollewerk, Angelika   +18 more
openaire   +5 more sources

The plastic response of magnetoelastic amorphous solids [PDF]

open access: yesEPL (Europhysics Letters), 2012
We address the cross effects between mechanical strains and magnetic fields on the plastic response of magnetoelastic amorphous solids. It is well known that plasticity in non-magnetic amorphous solids under external strain $γ$ is dominated by the co-dimension 1 saddle-node bifurcation in which an eigenvalue of the Hessian matrix vanishes at $γ_P$ like
H. G. E. Hentschel   +2 more
openaire   +2 more sources

Optimization for energy response characteristics of plastic scintillators based on genetic algorithm

open access: yesAIP Advances, 2022
To address the problem that the energy response of the plastic scintillator detector is very low in the low energy range, this paper proposes a method to optimize the energy response characteristics by combining the CaWO4 energy compensation layer and ...
Zhongliang Li   +4 more
doaj   +1 more source

The Evolution of Phenotypic Plasticity in Response to Temperature Stress [PDF]

open access: yesGenome Biology and Evolution, 2020
Abstract Phenotypic plasticity is the ability of a single genotype to produce different phenotypes in response to environmental variation. The importance of phenotypic plasticity in natural populations and its contribution to phenotypic evolution during rapid environmental change is widely debated.
Francois Mallard   +2 more
openaire   +3 more sources

Dynamic Response Analyses of Plastic Greenhouse Structure considering Fluctuating Wind Load

open access: yesAdvances in Civil Engineering, 2021
Wind load is one of the main factors of plastic greenhouse collapse. To solve the dynamic response problem of greenhouses under wind load and determine the dangerous section of a skeleton structure, the investigated lump method is presented for the ...
Yingchun Jiang   +4 more
doaj   +1 more source

Gauging the Effectiveness and Translatability of Oil Spill Response Technologies to Plastic Pellet Spills

open access: yesMicroplastics
Plastic pellet spills are a growing environmental concern, yet response strategies remain limited and poorly adapted. This study evaluates whether existing oil spill recovery tools, including booms, skimmers, and specialized vessels, can be repurposed to
Marko Jugo   +3 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Closed-form critical earthquake response of elastic-plastic structures on compliant ground under near-fault ground motions

open access: yesFrontiers in Built Environment, 2016
The double impulse is introduced as a substitute of the fling-step near-fault ground motion. A closed-form solution of the elastic-plastic response of a structure on compliant (flexible) ground by the ‘critical double impulse’ is derived for the first ...
Kotaro eKojima, Izuru eTakewaki
doaj   +1 more source

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