Mepce Restrains Ferroptosis in Prostate Cancer Through 7SK–P‐TEFb Pause Control
Advanced Science, EarlyView.Genome‐wide CRISPR screening identifies MEPCE as a pause‐control regulator that restrains ferroptosis in prostate cancer. MEPCE loss releases P‐TEFb/CDK9 from 7SK snRNP control, enhances RNAPII Ser2 phosphorylation, and accelerates NRF2‐HMOX1‐driven labile iron accumulation and lipid peroxidation, revealing a transcriptional kinetic gate that lowers ...
Tongtong Zhang +9 more
wiley +1 more source
Minimization of Welding Distortion in Large-Scale Welded Structures Using the MAG Method: Numerical and Physical Simulation of the Welding Process. [PDF]
Materials (Basel)Mróz M, Czech R, Pikuła J, Spólnik M.
europepmc +1 more source
Developing Soft Interconnected Microchannel Network for 2D Skin‐Like Actuator
Advanced Science, EarlyView.A soft interconnected network of microchannels is proposed to develop new pneumatic actuators for future bio‐inspired soft robots. Simultaneous stimulation of this network generates regional asymmetric strains in walls of microchannels whose interaction across the entire surface leads to bending curvatures in multidimensions.
John Noee +4 more
wiley +1 more source
Effect of Cooling Time on Demoulding Temperature, Shrinkage and Warpage of Injection-Moulded Polypropylene Parts. [PDF]
Polymers (Basel)Kleinsorge J, Ollig-Gaul YL, Hopmann C.
europepmc +1 more source
Early-Age Shrinkage Monitoring of 3D-Printed Cementitious Mixtures: Comparison of Measuring Techniques and Low-Cost Alternatives. [PDF]
Materials (Basel)Federowicz K +4 more
europepmc +1 more source
Advanced Science, EarlyView.A large‐area, noise‐resilient multiplexed triboelectric sensing garment based on a multilayer shielded architecture and SnS2 nanoflower‐engineered hybrid materials enables interference‐suppressed, high‐fidelity full‐body motion tracking, achieving 0.13% signal misrecognition, 57 dB electromagnetic noise attenuation, and >1.5 N threshold force, while ...
Beibei Shao +14 more
wiley +1 more source
Comparative Study of the Geometric Accuracy of 3D-Printed Polyamide CF15 and Injection-Molded POM Spur Gears. [PDF]
Materials (Basel)Bakardzhiev V +4 more
europepmc +1 more source
Advanced Science, EarlyView.LDHA‐driven lactate production in mesenchymal glioma stem cells promotes p300‐dependent H3K18 lactylation, activates USP30 transcription, and stabilizes MBOAT2 to remodel phosphatidylethanolamines toward ferroptosis‐resistant PE‐MUFA species. Disrupting this metabolic–epigenetic–lipid circuit enhances ferroptosis and sensitizes glioblastoma to ...
Zong Miao +13 more
wiley +1 more source
Improving the Volume Stability of Low-Carbon Ultra-High Performance Concrete Through the Employment of Internal Curing. [PDF]
Materials (Basel)Zhang Y +5 more
europepmc +1 more source